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| 1 | 胰腺导管腺癌放射学报告模板:腹部放射协会和美国胰腺协会的共识声明显示文摘胰腺导管腺癌(PDA)是一种具有侵袭性、死亡率高的恶性肿瘤。在肿瘤分期时,通过影像学分析,合理判定肿瘤的范围,是患者治疗措施中最重要的步骤之一。考虑到不同医生在专业知识水平和疾病严重程度的判定有所差异,以及在放射学检查时经常缺乏相关影像学表现的完整报道,有必要采用标准化的影像学报告模板以及大家一致接受和认可的胰腺实性肿瘤术语。在腹部放射协会和美国胰腺协会的共同资助下,胰腺导管腺癌(PDA)多机构专家组(包括放射学专家、胃肠病学和肝胆胰外科学专家)共同发起了一份描述标准化报告模板的共识声明。采用这种标准化的影像学报告模板将能改进PDA患者的治疗决策过程,并可通过提供一份完整、相关、精准的疾病分期报告以优化治疗方案。通过对可行手术切除的患者恰当、一致的分期,标准化报告模板有助于促进临床和科研实验设计,从而实现在不同机构之间的实验结果的比较。 | Mahmoud M.Al-Hawary Isaac R.Francis Suresh T.Chari Elliot K.Fishman David M.Hough David S.Lu Michael Macari Alec J.Megibow Frank H.Miller Dushyant V.Sahani Diane M.Simeone 黄翔 孙灿辉 | 2014 | 影像诊断与介入放射学2014，23，4： | 52 |
| 2 | Autoimmune pancreatitis in the context of IgG4-related disease:Review of imaging findings显示文摘Current understanding of autoimmune pancreatitis(AIP) recognizes a histopathological subtype of the disease to fall within the spectrum of IgG4-related disease.Along with clinical,laboratory,and histopathological data,imaging plays an important role in the diagnosis and management of AIP,and more broadly,within the spectrum of IgG4-related disease.In addition to the defined role of imaging in consensus diagnostic protocols,an array of imaging modalities can provide complementary data to address specific clinical concerns.These include contrast-enhanced computed tomography(CT) and magnetic resonance(MR) imaging for pancreatic parenchymal lesion localization and characterization,endoscopic retrograde and magnetic resonance cholangiopancreatography(ERCP and MRCP) to assess for duct involvement,and more recently,positron emission tomography(PET) imaging to assess for extra-pancreatic sites of involvement.While the imaging appearance of AIP varies widely,certain imaging features are more likely to represent AIP than alternate diagnoses,such as pancreatic cancer.While nonspecific,imaging findings which favor a diagnosis of AIP rather than pancreatic cancer include:delayed enhancement of affected pancreas,mild dilatation of the main pancreatic duct over a long segment,the 'capsule' and 'penetrating duct' signs,and responsiveness to corticosteroid therapy.Systemic,extra-pancreatic sites of involvement are also often seen in AIP and IgG4-related disease,and typically respond to corticosteroid therapy.Imaging by CT,MR,and PET also play a role in the diagnosis and monitoring after treatment of involved sites. | Leslie K Lee Dushyant V Sahani | 2014 | World Journal of Gastroenterology2014，20，41： | 23 |
| 3 | Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma:Radiologic-pathologic correlation显示文摘AIM:To identify multi-detector computed tomography(MDCT) features most predictive of serous cystadenomas(SCAs),correlating with histopathology,and to study the impact of cyst size and MDCT technique on reader performance.METHODS:The MDCT scans of 164 patients with surgically verified pancreatic cystic lesions were reviewed by two readers to study the predictive value of various morphological features for establishing a diagnosis of SCAs.Accuracy in lesion characterization and reader conf idence were correlated with lesion size(≤3cm or≥3cm) and scanning protocols(dedicated vs routine).RESULTS:28/164 cysts(mean size,39 mm;range,8-92mm) were diagnosed as SCA on pathology.The MDCT features predictive of diagnosis of SCA were microcystic appearance(22/28,78.6%),surface lobulations(25/28,89.3%) and central scar(9/28,32.4%).Stepwise logistic regression analysis showed that only microcystic appearance was signifi cant for CT diagnosis of SCA(P=0.0001).The sensitivity,specificity and PPV of central scar and of combined microcystic appearance and lobulations were 32.4%/100%/100% and 68%/100%/100%,respectively.The reader confidence was higher for lesions>3cm(P=0.02) and for MDCT scans performed using thin collimation(1.25-2.5mm) compared to routine 5 mm collimation exams(P>0.05).CONCLUSION:Central scar on MDCT is diagnostic of SCA but is seen in only one third of SCAs.Microcystic morphology is the most significant CT feature in diagnosis of SCA.A combination of microcystic appearance and surface lobulations offers accuracy comparable to central scar with higher sensitivity. | Anjuli A Shah Nisha I Sainani Avinash Kambadakone Ramesh Zarine K Shah Vikram Deshpande Peter F Hahn Dushyant V Sahani | 2009 | World Journal of Gastroenterology2009，15，22： | 11 |
| 4 | Computed tomography perfusion imaging as a potential imaging biomarker of colorectal cancer显示文摘Neovascularization was reported to arise early in the adenoma-carcinoma sequence in colorectal cancer(CRC),and the importance of angiogenesis in cancer progression has been established.Computed tomography(CT)perfusion(CTP)based on high temporal resolution CT images enables evaluation of hemodynamics of tissue in vivo by modeling tracer kinetics.CTP has been reported to characterize tumor angiogenesis,and to be a sensitive marker for predicting recurrence or survival in CRC.In this review,we will discuss the biomarker value of CTP in the management of CRC patients. | Koichi Hayano Takeshi Fujishiro Dushyant V Sahani Asami Satoh Tomoyoshi Aoyagi Gaku Ohira Toru Tochigi Hisahiro Matsubara Kiyohiko Shuto | 2014 | World Journal of Gastroenterology2014，20，46： | 5 |
| 5 | New approaches for precise response evaluation in hepatocellular carcinoma显示文摘With the increasing clinical use of cytostatic and novel biologic targeted agents,conventional morphologic tumor burden assessments,including World Health Organization criteria and Response Evaluation Criteria in Solid Tumors,are confronting limitations because of their difficulties in distinguishing viable tumor from necrotic or fibrotic tissue.Therefore,the investigation for reliable quantitative biomarkers of therapeutic response such as metabolic imaging or functional imaging has been desired.In this review,we will discuss the conventional and new approaches to assess tumor burden.Since targeted therapy or locoregional therapies can induce biological changes much earlier than morphological changes,these functional tumor burden analyses are very promising.However,some of them have not gone thorough all steps for standardization and validation.Nevertheless,these new techniques and criteria will play an important role in the cancer management,and provide each patient more tailored therapy. | Koichi Hayano Jorge M Fuentes-Orrego Dushyant V Sahani | 2014 | World Journal of Gastroenterology2014，20，12： | 4 |
| 6 | Monitoring Response to Antiangiogenic Treatment and Predicting Outcomes in Advanced Hepatocellular Carcinoma Using Image Biomarkers, CT Perfusion, Tumor Density, and Tumor Size (RECIST)显示文摘 | Tao Jiang Avinash Kambadakone Naveen M. Kulkarni Andrew X. Zhu Dushyant V. Sahani | 2012 | Investigative Radiology2012，，1： | 3 |
| 7 | 胰腺偶发囊肿的管理--美国放射学院(ACR)偶发病变委员会白皮书显示文摘美国放射学院(American College of Radiology,ACR)偶发病变委员会(Incidental Findings Committee,IFC)发布了CT或MR偶发胰腺囊肿的管理建议。该建议是对美国放射学院杂志(JACR)2010年发布的肾上腺、肾脏、肝脏以及胰腺偶发病变管理白皮书中胰腺部分的更新。该管理方案由多位腹部影像医师、1位胃肠道学医师以及1位胰腺外科医师所组成的胰腺亚组委员会制定。该方案参考已发表的文献和专家意见,经反复协商,最终达成共识。该方案的分支成功地根据患者的临床特点及影像特征将胰腺囊肿进行分类,评估终点为良性和/或进展缓慢病变的诊断(足以结束随访)或具体的管理建议。该方案适用于大多数但非全部的病理及临床情况。该方案旨在通过提供胰腺偶发囊肿的管理指导,来提高患者的管理质量。 | Alec J.Megibow Mark E.Baker Desiree E.Morgan Ihab R.Kamel Dushyant V.Sahani Elliot Newman William R.Brugge Lincoln L.Berland Pari V.Pandharipande 赵心明 曾蒙苏 薛华丹 刘再毅 石喻 | 2018 | 放射学实践2018，33，2： | 2 |
| 8 | Lymphoepithelial cysts and cystic lymphangiomas: Underrecognized benign cystic lesions of the pancreas显示文摘AIM: To identify their diagnostic and prognostic clinical characteristics in a large series.METHODS: Retrospective review of clinicopathologic and imaging characteristics of patients diagnosed with lymphoepithelial cysts and cystic lymphangiomas of the pancreas at Massachusetts General Hospital.RESULTS: Twelve patients were identified between 1/1/1997 and 8/1/2007. Their median age was 55.5 years(range 19-78 years), and 6 were females. The le-sion was incidentally discovered in half of the patients.Contrast enhanced computed tomography demonstrat-ed that the cysts had thin walls, without calcifications, pancreatic duct dilation or pancreatic parenchyma inva-sion. Endoscopic ultrasound with fine needle aspiration(EUS/FNA) confirmed the diagnosis of a lymphoepithe-lial cyst in 3 patients, one of whom was spared an op-eration and continues to do well after 6 years. Eleven patients had a resection: 3 pancreaticoduodenecto-mies, 7 distal pancreatectomies, and 1 enucleation. The median size of the cysts was 3 cm(range 2-20 cm). At a median follow-up of 57 mo no recurrences or other pancreas-related conditions occurred.CONCLUSION: Lymphoepithelial cysts and cystic lymphangiomas of the pancreas can be diagnosed with a combination of contrast-enhanced computed tomog-raphy scans and EUS/FNA. If the lesion is asymptom-atic, an operation might be avoided. | Ioannis T Konstantinidis Avinash Kambadakone Onofrio A Catalano Dushyant V Sahani Vikram Deshpe David G Forcione Jennifer A Wargo Carlos Fernandez-del Castillo Keith D Lillemoe Andrew L Warshaw Cristina R Ferrone | 2014 | World Journal of Gastrointestinal Surgery2014，6，7： | 2 |
| 9 | Radiation Dose Reduction at Multidetector CT with Adaptive Statistical Iterative Reconstruction for Evaluation of Urolithiasis: How Low Can We Go?显示文摘 | Naveen M. Kulkarni Raul N. Uppot Brian H. Eisner Dushyant V. Sahani | 2012 | Radiology2012，，： | 2 |
| 10 | Association of non-alcoholic fatty liver disease with gallstone disease in the United States hospitalized patient population显示文摘BACKGROUND Gallstones and cholecystectomy have been proposed as risk factors for nonalcoholic fatty liver disease(NAFLD).The reason for this may be that both gallstones,as well as NAFLD share several risk factors with regards to their development.Currently,there is a lack of sufficient evidence showing an association between these clinical conditions.AIM To determine whether there is a meaningful association between gallstones and cholecystectomy with NAFLD.METHODS We queried the National Inpatient Sample database from the years 2016 and 2017 using International Classification of Diseases,10th revision,Clinical Modification diagnosis codes to identify hospitalizations with a diagnosis of gallstone disease(GSD)(includes calculus of gallbladder without cholecystitis without obstruction and acquired absence of gallbladder)as well as NAFLD(includes simple fatty liver and non-alcoholic steatohepatitis).Odds ratios(ORs)measuring the association between GSD(includes gallstones and cholecystectomy)and NAFLD were calculated using logistic regression after adjusting for confounding variables.RESULTS Out of 14294784 hospitalizations in 2016-2017,159259 were found to have NAFLD.The prevalence of NAFLD was 3.3%in patients with GSD and 1%in those without.NAFLD was prevalent in 64.3%of women with GSD as compared to 35.7%of men with GSD.After controlling for various confounders associated with NAFLD and GSD,multivariate-adjusted analysis showed that there was an association between NAFLD with gallstones[OR=6.32;95%confidence interval(CI):6.15-6.48]as well as cholecystectomy(OR=1.97;95%CI:1.93-2.01).The association between NAFLD and gallstones was stronger in men(OR=6.67;95%CI:6.42-6.93)than women(OR=6.05;95%CI:5.83-6.27).The association between NAFLD and cholecystectomy was stronger in women(OR=2.01;95%CI:1.96-2.06)than men(OR=1.85;95%CI:1.79-1.92).P value was less than 0.001 for all comparisons.CONCLUSION NAFLD is more prevalent in women with GSD than men.The association between NAFLD and cholecystectomy/gallstones indicates that they may be risk factors for NAFLD. | Asim Kichloo Shantanu Solanki Khwaja F Haq Dushyant Dahiya Beth Bailey Dhanshree Solanki Jagmeet Singh Michael Albosta Farah Wani Michael Aljadah Harshil Shah Hafiz Khan Syed-Mohammed Jafri | 2021 | World Journal of Gastrointestinal Pathophysiology2021，12，2： | 1 |
| 11 | Lowdose CT of the abdomen: evaluation of image improvement with use of noise reduction filters-pilot study显示文摘 | Mannudeep KK Michael MM Dushyant VS | 2003 | Radiology2003，228，1： | 1 |
| 12 | Imaging of the Renal Donor and Transplant Recipient显示文摘 | Anand K. Singh Dushyant V. Sahani | 2008 | Radiologic Clinics of North America2008，，1： | 1 |
| 13 | Analysis of RC beams strengthened with mechanically fastened FRP strips显示文摘 | LAWRENCE CBANK DUSHYANT ARORA | 2007 | Composite Structure2007，79，： | 1 |
| 14 | Reproductive toxicity of di-n-butylphalate in a continuous breeding protocol in Sprague-Dawley rats显示文摘 | Robert N Ling-Hong Li Lete Dushyant K | 1997 | Environ Health Perspect1997，105，1： | 1 |
| 15 | Incidence & outcome of aluminium phosphide poisoning in ahospital study显示文摘 | Chugh SN Dushyant Ram S | 1991 | Indian J Med Res1991，94，： | 1 |
| 16 | Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors显示文摘 | Lorraine C. Axford Piyush K. Agarwal Kelly H. Anderson Laura N. Andrau John Atherall Stephanie Barker James M. Bennett Michael Blair Ian Collins Lloyd G. Czaplewski David T. Davies Carlie T. Gannon Dushyant Kumar Paul Lancett Alastair Logan Christopher J. | 2013 | Bioorganic & Medicinal Chemistry Letters2013，，24： | 1 |
| 17 | Multidetector-row Computed Tomography Angiography for Planning Intra-arterial Chemotherapy Pump Placement in Patients with Colorectal Metastases to the Liver显示文摘 | Dushyant V Saravanan K Sanjeeva K | 2004 | J Comput Assist Tomogr2004，28，4： | 1 |
| 18 | Gallbladder Lesions Identified on Ultrasound. Lessons from the Last 10?Years显示文摘 | Ioannis T. Konstantinidis Surabhi Bajpai Avinash R. Kambadakone Kenneth K. Tanabe David L. Berger Hui Zheng Dushyant V. Sahani Gregory Y. Lauwers Carlos Fernandez-del Castillo Andrew L. Warshaw Cristina R. Ferrone | 2012 | Journal of Gastrointestinal Surgery2012，，3： | 1 |
| 19 | Pixel distribution analysis:Can it be used to distinguish clear cell carcinomas from angiomyolipomas with minimal fat显示文摘 | Onofrio A Anthony E Dushyant V | | 0，，： | 1 |
| 20 | Reducing Abdominal CT Radiation Dose With Adaptive Statistical Iterative Reconstruction Technique显示文摘 | Priyanka Prakash Mannudeep K. Kalra Avinash K. Kambadakone Homer Pien Jiang Hsieh Michael A. Blake Dushyant V. Sahani | 2010 | Investigative Radiology2010，，4： | 1 |
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