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| 1 | Mesenchymal stem cells as a therapeutic tool to treat sepsis显示文摘Sepsis is a clinical syndrome caused by a deregulated host response to an infection. Sepsis is the most frequent cause of death in hospitalized patients. Although knowledge of the pathogenesis of sepsis has increased substantially during the last decades, attempts to design effective and specific therapiestargeting components of the derailed host response have failed. Therefore, there is a dramatic need for new and mechanistically alternative therapies to treat this syndrome. Based on their immunomodulatory properties, adult mesenchymal stem or stromal cells(MSCs) can be a novel therapeutic tool to treat sepsis. Indeed, MSCs reduce mortality in experimental models of sepsis by modulating the deregulated inflammatory response against bacteria through the regulation of multiple inflammatory networks, the reprogramming of macrophages and neutrophils towards a more antiinflammatory phenotype and the release of antimicrobial peptides. This report will review the current knowledge on the effects of MSC treatment in preclinical experimental small animal models of sepsis. | Eleuterio Lombardo Tom van der Poll Olga Dela Rosa Wilfried Dalemans | 2015 | World Journal of Stem Cells2015，7，2： | 6 |
| 2 | Giardia and other intestinal parasites in different dog populations in Northern Belgium显示文摘 | Claerebout E Casaert S Dalemans AC | 2009 | Vet Parasitol2009，161，12： | 1 |
| 3 | Superiority of the earpinna overmuscle tissue as site for DNA vaccination 显示文摘 | Forg P von Hoegen P Dalemans W | 1998 | Gene Thero1998，5，6： | 1 |
| 4 | Evaluation of vaccines in the EUTB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis显示文摘 | Williams A Hatch GJ Clark SO Gooch KE Hatch KA Hall GA Huygen K Ottenhoff TH Franken KL Andersen P Doherty TM Kaufmann SH Grode L Seiler P Martin C Gicquel B Cole ST Brodin P Pym AS Dalemans W Cohen J Lobet Y Goonetilleke N McShane H Hill A Parish T Smith D Stoker NG Lowrie DB Kallenius G Svenson S Pawlowski A Blake K Marsh PD | 2005 | Tuberculosis (Edinb)2005，85，12： | 1 |
| 5 | Defined tuberculosis vaccinej Mtb72F/AS02A, evidence of protection in cynomolgusmonkeys显示文摘 | Reed SG Coler RN Dalemans W | 2009 | Proc Natl Acad Sci USA2009，106，7： | 1 |
| 6 | Toll-like receptors as modulators of mesenchymal stem cells显示文摘 | Delarosa 0 Dalemans W Lombardo E | 2012 | Front Immunol2012，3，： | 1 |
| 7 | Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys显示文摘 | Reed SG Coler RN Dalemans W | 2009 | ProcNatlAcad SciUSA2009，106，7： | 1 |
| 8 | Superiority of the ear pinna over muscle tissue as site for DNA vaccination 显示文摘 | Forg P von Hoegen P Dalemans W | 1998 | Gene Ther1998，，5： | 1 |
| 9 | An Investi- gation into the Social Participation of Stroke Survivors with Aphasia显示文摘 | Dalemans R J De Witte L P Beurskens A J | 2010 | Disabil Rehabil2010，32，20： | 1 |
| 10 | Defined tuberculosis vaccine,Mtb72F/AS02A,evidence of protection in cynomolgus monkeys显示文摘 | Reed SG Coler RN Dalemans W | | 0，，： | 1 |
| 11 | Superiority of the ear Pinna Over Muscle Tissue as Site for DNA Vaccination显示文摘 | von Hoegen P Dalemans W | 1998 | Gene Ther1998，5，6： | 1 |
| 12 | Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6 显示文摘 | Langermans JA Doherty TM Vervenne RA van der Laan T Lyashchenko K Greenwald R Agger EM Aagaard C Weiler H van Soolingen D Dalemans W Thomas AW Andersen P | 2005 | Vaccine2005，23，21： | 1 |
| 13 | Superiority of the ear pin- na over muscle tissue as site for DNA vaccination 显示文摘 | FSrg P von Hoegen P Dalemans W | 1998 | Gene Ther1998，5，6： | 1 |
| 14 | Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys显示文摘 | Reed SG Coler RN Dalemans W | 2009 | Proc Nail Acad Sci USA2009，106，7： | 1 |
| 15 | Defined tuberculosis vaccine,Mtb72F/AS02A, evidence of protection in cynomolgus monkeys显示文摘 | Reed SG Coler RN Dalemans W | 2009 | Proc Natl Acad Sci USA2009，106，7： | 1 |
| 16 | Mixed Giardia du- odenalis assemblage A, B, C and E infections in pet chinchillas (Chinchilla lanigera) in Flanders (Belgium) 显示文摘 | Levecke B Meulemans L Dalemans T | 2011 | Vet Parasi- tol2011，177，12： | 1 |
| 17 | Superiority of the ear pinna over muscle tissue as site for DNA vaccination显示文摘 | Forg P von Hoegen P Dalemans W | 1998 | Gene Ther1998，5，： | 1 |
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