维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

14篇 您的检索式：作者名="Damazo"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Prognostic significance of vascular endothelial growth factor polymorphisms in colorectal cancer patients显示文摘AIM To investigate the associations of the genetic polymor-phisms of vascular endothelial growth factor A(VEGF-A)-1498C>T and-634G>C, with the survival of patients with colorectal cancer(CRC). METHODS A prospective cohort consisting of 131 Brazilians patients consecutively operated on with a curative intention as a result of sporadic colorectal carcinoma was studied. DNA was extracted from peripheral blood and its amplification and allelic discrimination for each genetic polymorphism was performed using the technique of polymerase chain reaction(PCR) in real-time. The real-time PCR technique was used to identify the VEGF-A-1498C>T(rs833031) and-634G>C(rs2010963) polymorphisms. Genotyping was validated for VEGF-A-1498C>T polymorphism in 129 patients and for VEGF-A-634G>C polymorphism in 118 patients. The analysis of association between categorical variables was performed using logistic regression, survival by Kaplan-Meier method and multivariate analysis by the Cox regression method. RESULTS In the univariate analysis there was a significant association(OR = 0.32; P = 0.048) between genotype CC of the VEGF-A-1498C>T polymorphism and the presence of CRC liver metastasis. There was no association between VEGF-A-1498C>T polymorphism and VEGF-A-634G>C polymorphism with further clinical or anatomopathologic variables. The genotype CC of the VEGF-A-1498C>T polymorphism was significantly correlated with the 5-year survival(P = 0.032), but not significant difference(P = 0.27) was obtained with the VEGF-A-634G>C polymorphism with the 5-year survival in the univariate analysis. The genotype CT(HR = 2.79) and CC(HR = 4.67) of the polymorphism VEGF-A-1498C>T and the genotype CC(HR = 3.76) of the polymorphism VEGF-A-634C>G acted as an independent prognostic factor for the risk of death in CRC patients. CONCLUSION The CT and CC genotypes of the VEGF-A-1498C>T and the CC genotype of the VEGF-A-634C>G polymorphisms are prognostic factors of survival in Brazilians patients with sporadic colorectal carcinoma.	Gilmar Ferreira do Espírito Santo Bianca Borsatto Galera Elisabeth Carmen Duarte Elisabeth Suchi Chen Lenuce Azis Amilcar Sabino Damazo Gabriela Tognini Saba Flávia de Sousa Gehrke Ismael Dale Cotrim Guerreiro da Silva Jaques Waisberg	2017	World Journal of Gastrointestinal Oncology2017，9，2：	4
	2	Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation 显示文摘	Damazo AS Yona S D'Acquisto F	2005	Am J Pathol2005，166，6：	1
	3	Fluctuation of annexin-A1 positive mast cells in chronic granulomatous inflammation显示文摘	S. M. Oliani G. A. Panin Ciocca T. A. Pimentel A. S. Damazo L. Gibbs M. Perretti	2008	Inflammation Research2008，，10：	1
	4	Endogenous annexinA1 counter-regulates bleomycin-induced lung fibrosis显示文摘	Damazo AS Sampaio AL Nakata CM	2011	BMCImmunol2011，12，1：	1
	5	Endogenous annexin Alcounter-regulates bleomycin-induced lung flbrosis 显示文摘	Damazo AS Sampaio AL Nakata CM	2011	BMC Immu-nol2011，12，5：	1
	6	Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation 显示文摘	Gastardelo TS Damazo AS Dalli J	2009	Am J Pathol2009，174，1：	1
	7	Effect of annexin-A1 peptide treatment during lung inflammation induced by lipopolysaccharide显示文摘	Da C E Oliani S M Damazo A S	2012	Pulm Pharmacol Ther2012，25，4：	1
	8	Analysis of lymphocytes in patients with Plasmodium vivax malaria and its relation to the annexin-Al and IL-lO显示文摘	Borges Q I Fontes CJ Damazo A S	2013	MalarJ2013，12，455：	1
	9	Functional and ultrastructural analysis of armexin A1 and its receptor in extravasating neutroptfils during acute inflammation显示文摘	Gastardelo TS Damazo AS DalliJ	2009	AmJ Pathol2009，174，1：	1
	10	Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis显示文摘	Damazo A S Sampaio A L Nakata C M	2011	BMC Immunol2011，12，：	1
	11	Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation 显示文摘	Gastardelo TS Damazo AS Dalli J	2009	Am J pathol2009，174，1：	1
	12	Functional and ultra- structural analysis of annexin AI and its receptor in extravasating neutrophils during acute inflammation显示文摘	Gastardelo TS Damazo AS Dalli J	2009	Am J Pathol2009，174，1：	1
	13	Role of Annexin 1 gene expression in mouse craniofacial bone development显示文摘	Damazo AS Moradi BN Oliani SM	2007	Birth De- fects Res AClin Mol Terato12007，79，7：	1
	14	Functional and uhra- structural analysis of annexin A1 and its receptor in extravasating- neutrophils during acute inflammation 显示文摘	Gastardelo TS Damazo AS Dalli J	2009	Am J Pathol2009，174，1：	1

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费