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| 1 | An experimental analysis of situation awareness for cockpit display interface evaluation based on flight simulation显示文摘Aircraft cockpit display interface (CDI) is one of the most important human-machine interfaces for information perceiving. During the process of aircraft design, situation awareness (SA) is frequently considered to improve the design, as the CDI must provide enough SA for the pilot to maintain the flight safety. In order to study the SA in the pilot-aircraft system, a cockpit flight simulation environment is built up, which includes a virtual instrument panel, a flight visual display and the corresponding control system. Based on the simulation environment, a human-in-the-loop experiment is designed to measure the SA by the situation awareness global assessment technique (SAGAT). Through the experiment, the SA degrees and heart rate (HR) data of the subjects are obtained, and the SA levels under different CDI designs are analyzed. The results show that analyzing the SA can serve as an objective way to evaluate the design of CDI, which could be proved from the consistent HR data. With this method, evaluations of the CDI design are performed in the experimental flight simulation environment, and optimizations could be guided through the analysis. | Wei Hengyang Zhuang Damin Wanyan Xiaoru Wang Qun | 2013 | Chinese Journal of Aeronautics2013,26,4: | 23 |
| 2 | A model for discrimination and prediction of mental workload of aircraft cockpit display interface显示文摘With respect to the ergonomic evaluation and optimization in the mental task design of the aircraft cockpit display interface, the experimental measurement and theoretical modeling of mental workload were carried out under flight simulation task conditions using the performance evaluation, subjective evaluation and physiological measurement methods. The experimental results show that with an increased mental workload, the detection accuracy of flight operation significantly reduced and the reaction time was significantly prolonged; the standard deviation of R-R intervals(SDNN) significantly decreased, while the mean heart rate exhibited little change; the score of NASA_TLX scale significantly increased. On this basis, the indexes sensitive to mental workload were screened, and an integrated model for the discrimination and prediction of mental workload of aircraft cockpit display interface was established based on the Bayesian Fisher discrimination and classification method. The original validation and cross-validation methods were employed to test the accuracy of the results of discrimination and prediction of the integrated model, and the average prediction accuracies determined by these two methods are both higher than 85%. Meanwhile, the integrated model shows a higher accuracy in discrimination and prediction of mental workload compared with single indexes. The model proposed in this paper exhibits a satisfactory coincidence with the measured data and could accurately reflect the variation characteristics of the mental workload of aircraft cockpit display interface, thus providing a basis for the ergonomic evaluation and optimization design of the aircraft cockpit display interface in the future. | Wei Zongmin Zhuang Damin Wanyan Xiaoru Liu Chen Zhuang Huan | 2014 | Chinese Journal of Aeronautics2014,27,5: | 17 |
| 3 | Evolving treatment strategies for colorectal cancer: A critical review of current therapeutic options显示文摘Management of rectal cancer has markedly evolved over the last two decades.New technologies of staging have allowed a more precise definition of tumor extension.Refinements in surgical concepts and techniques have resulted in higher rates of sphincter preservation and better functional outcome for patients with this malignancy.Although,preoperative chemoradiotherapy followed by total mesorectal excision has become the standard of care for locally advanced tumors,many controversial matters in management of rectal cancer still need to be defined.These include the feasibility of a non-surgical approach after a favorable response to neoadjuvant therapy,the ideal margins of surgical resection for sphincter preservation and the adequacy of minimally invasive techniques of tumor resection.In this article,after an extensive search in PubMed and Embase databases,we critically review the current strategies and the most debatable matters in treatment of rectal cancer. | Daniel C Damin Anderson R Lazzaron | 2014 | World Journal of Gastroenterology2014,20,4: | 10 |
| 4 | Information Coding for Cockpit Human-machine Interface显示文摘Pilot needs to process lots of information when operating an aircraft, and reasonable information coding can greatly improve the correct rate and speed of information identification. At present, related researches are mainly performed in the laboratory, and the experiment method for abstract simulation is often used to research single digit information coding. The research results demonstrate a lack of systematization and applicability. The present study is based upon information coding methods of human-machine interface under real time in flight simulators. Subjects are required to perform an aircraft landing and the corresponding experiment task. The correct rate and reaction time are chosen as the performance evaluation indexes, combined with eye movement data. The advantages and disadvantages of different information coding methods are also evaluated and analyzed. The experiment results demonstrate that the effect of color coding on the correct rate of information identification is not significant, but the effect on the speed of information identification is obviously significant. The study demonstrates that on a black background, red, green and yellow are suitable colors for color coding, but blue is not. The position of information on the performance of information identification is also significant. The center of the interface is better than the edge, and the left position is superior to the right. The impact of language and a person's mother tongue should also be considered in practical applications. The study shows that the Chinese has a higher correct rate of identification than English. As the experiment research method in the present study is based on flight simulator, the actual utility and application value can be guaranteed. The research results have the ability to offer improvements in ergonomic reference for cockpit human-machine interface design. | ZHANG Lei ZHUANG Damin WANYAN Xiaoru | 2011 | Chinese Journal of Mechanical Engineering2011,24,4: | 7 |
| 5 | pRB expression in esophageal mucosa of individuals at high risk for squamous cell carcinoma of the esophagus显示文摘AIM: To investigate the pRb expression in a large group of patients with history of chronic exposure to the main risk factors for development of squamous cell carcinoma of the esophagus. METHODS: One hundred and seventy asymptomatic individuals at high risk for esophageal squamous cell carcinoma (consumption of more than 80 g of ethanol and 10 cigarettes/d for at least 10 years) underwent upper gastrointestinal endoscopy with biopsies of the esophageal mucosa. As a control group, specimens of esophageal mucosa obtained from 20 healthy subjects were also studied. Immunohistochemical assessment of the tissues was performed using a monoclonal antibody anti-pRB protein. RESULTS: Absence of the pRB staining, indicating loss of RB function, was observed in 33 (19.4%) of the individuals at risk for esophageal cancer, but in none of the healthy controls (P < 0.02). Loss of pRb expression increased in a stepwise fashion according to the severity of the histological findings (P < 0.005): normal mucosa (11/97 or 11.3%), chronic esophagitis (17/60 or 28.3%), low-grade dysplasia (3/10 or 30%), high-grade dysplasia 1/2 or 50%) and squamous cell carcinoma (1/1 or 100%). CONCLUSION: Our findings suggest that abnormal expression of the pRB protein may be implicated in the process of esophageal carcinogenesis. Additional studies are warranted to define the role of the pRBprotein as a biomarker for development of esophageal squamous cell carcinoma in individuals at high risk for this malignancy. | Simone S Contu Paulo C Contu Daniel C Damin Renato B Fagundes Fabiano Bevilacqua Aline S Rosa Joo C Prolla Luis F Moreira | 2007 | World Journal of Gastroenterology2007,13,11: | 5 |
| 6 | CS_2 extraction and FTIR & GC/MS analysis of a Chinese brown coal显示文摘The abundance of low-rank coals in China, such as bituminous and brown coals, makes studies of their composition and structure of great significance to both coal chemistry research and for efficient utilization of the coal. We describe how a Chinese brown coal was ultrasonically extracted with carbon disulfide (CS2) and the raw and extracted coals were characterized by Fourier Transform Infrared Spectroscopy (FTIR). The corresponding extract was analyzed with a coupled gas chromatograph mass spectrometer (GC/MS). The FTIR analysis shows a great abundance of amidocyanogen, carbonyl, aromatic and hetero aromatic rings and single carbon-heteroatom bonds. This suggests the possible occurrence of compounds like alcohols, phenols, amines, esters, carboxylic acids, ethers, aromatics or heteroaromatics. The GC/MS analysis of the CS2 extract detected 62 compounds, among which the non-polar ones were of lower abundance while the polar ones were in higher abundance and were structurally diverse. This demonstrates the compositional and structural complexity of Shengli coal. | TIAN Damin LIU Xiangyun DING Mingjie | 2010 | Mining Science and Technology2010,20,4: | 4 |
| 7 | Identification of patients at-risk for Lynch syndrome in a hospital-based colorectal surgery clinic显示文摘AIM:To determine the prevalence of a family history suggestive of Lynch syndrome (LS) among patients with colorectal cancer (CRC) followed in a coloproctology outpatient clinic in Southern Brazil.METHODS:A consecutive sample of patients with CRC were interviewed regarding personal and family histories of cancer.Clinical data and pathology features of the tumor were obtained from chart review.RESULTS:Of the 212 CRC patients recruited,61 (29%) reported a family history of CRC,45 (21.2%) were diagnosed under age 50 years and 11 (5.2%) had more than one primary CRC.Family histories consistent with Amsterdam and revised Bethesda criteria for LS were identified in 22 (10.4%) and 100 (47.2%) patients,respectively.Twenty percent of the colorectal tumors had features of the high microsatellite instability phenotype,which was associated with younger age at CRC diagnosis and with Bethesda criteria (P < 0.001).Only 5.3% of the patients above age 50 years had been previously submitted for CRC screening and only 4% of patients with suspected LS were referred for genetic risk assessment.CONCLUSION:A significant proportion of patients with CRC were at high risk for LS.Education and training of health care professionals are essential to ensure proper management. | Patrícia Koehler-Santos Patricia Izetti Jamile Abud Carlos Eduardo Pitroski Silvia Liliana Cossio Suzi Alves Camey Cláudio Tarta Daniel C Damin Paulo Carvalho Contu Mario Antonello Rosito Patricia Ashton-Prolla Joāo Carlos Prolla | 2011 | World Journal of Gastroenterology2011,17,6: | 2 |
| 8 | Synthesis and Structural Determination of Nine-Coordinate K[Gd~Ⅲ(edta)(H_2O)_3]·5H_2O显示文摘The title complex K [GdⅢ(edta)(H2O)3]·5H2O was synthesized, where edta denotes ethylenediamine- tetraacetic acid. The crystal and molecular structure of the complex were determined by single-crystal X-ray structure analysis. The crystal belongs to an orthorhombic crystal system and an Fdd2 space group. The complex anion [GdⅢ(edta)(H2O)3] has a pseudo-monocapped square antiprismatic nine-coordinate structure in which six coordinate atoms (two N and four O) are from an edta ligand and three water molecules coordinate to GdⅢ ion directly. It can be predicted that GdⅢ ion can also form a nine-coordinate complex with ttha (triethylenetetraminehexaacetic acid) li- gand, so the GdⅢ complex anion [Gd?é¨(r)(Httha)]£¨2-£(c) can supply a free non-coordinate carboxyl group (-C-CH2COOH) used for molecular embellishment in some biological molecules to form a contrast agent of Magnetic Resonance Imagine (MRI) with targeting function. | Jun Wang, Xiangdong Zhang, Damin Fan, Xiao Ling Department of Chemistry, Liaoning University, Shenyang 110036, China | 2001 | Rare Metals2001,20,4: | 2 |
| 9 | PULSED Nd-YAG LASER WELDING OF AN AI-SiC_p METAL MATRIX COMPOSITE显示文摘A study is presented of the laser welding behaviour of an SiC particulate re-inforced Al-alloy comPOsite using a pulsed Nd-YAG laser. The influences of laser weldingparameters of laser intensity, pulse duration and the beamjs focus position on the depth ofweld penetration as well as the size of weld bead width were investigated. A typical mi-crostructure of a weld section reveals that the three distinct zones are present. Cracks andporosity were fOund to be two major defects in laser welded metal matrix composites(MMC). These investigations have led to an optimum welding condition proposed forlaser welding of SiC partiulate reinforced aluminium alloy comPosites with minimum de-fects. | Xu Jiukua Jiang Chengyu(Mechanical Engineering Institute, Nanjing University of Aeronauticsand Astronautics, Nanjing, 210016, China)Yu Damin Liu Weicheng(Department of Manufacturing Engineering, Hong Kong Polytechnic University) | 1997 | Chinese Journal of Aeronautics1997,10,1: | 2 |
| 10 | Evidence for an association of human papillomavirus and breast carcinomas显示文摘 | Damin A P Karam R Zettler C G | 2004 | Breast Cancer Res Treat2004,84,2: | 1 |
| 11 | Prevalence of the American College of Rheumatology hematological classification criteria and associations with serological and clinical variables in 460systemic lupus erythematosus patients显示文摘 | Skare T Damin R Hofius R | 2015 | Rev Bras Hematol Hemoter2015,37,2: | 1 |
| 12 | Evidence for an Association of Human Papillomavirus and Breast Carcinomas显示文摘 | Andrea P.S. Damin Rachid Karam Claudio G. Zettler Maira Caleffi Claudio O.P. Alexandre | 2004 | Breast Cancer Research and Treatment2004,,2: | 1 |
| 13 | Evidence for an association of human papillomavirus infection and colorectal cancer显示文摘 | Damin DC Caetano MB Rosito MA | 2007 | Eur J Surg Oncol2007,33,: | 1 |
| 14 | Characterization of poly(dimethylacrylamide) and the combination of poly(vinyl alcohol) and cetyltrimethylammonium bromide as dynamic electroosmotic flow suppression agents in capillary electrophoresis显示文摘 | Damin F Reijenga J C | 1998 | J Chromatogr A1998,817,: | 1 |
| 15 | Sentinel lymph node in carcinoma of the anal canal显示文摘 | Damin DC Rosito MA Schwartsmann G | 2006 | Eur J Surg Oncol2006,32,3: | 1 |
| 16 | Measuring the eco-efficiency of cement use 显示文摘 | Damineli B L Kemeid F M Aguiar P S | 2010 | Cement & Concrete Composites2010,32,: | 1 |
| 17 | Evidence for an association of human papilloma virus and breast carcinomas显示文摘 | DAMIN A P KARAM R ZETTLER C G | 2004 | Breast Cancer Res Treat2004,84,2: | 1 |
| 18 | Late Complication of Laparoscopic Sleeve Gastrectomy显示文摘 | Anthony Dakwar Ahmad Assalia Iyad Khamaysi Yoram Kluger Ahmad Mahajna E. Altintas D. C. Damin | 2013 | Case Reports in Gastrointestinal Medicine2013,,: | 1 |
| 19 | New adsorbed coatings for capillary electrophoresis显示文摘 | CHIARI M CRETICH M DAMIN F | 2000 | Electrophoresis2000,21,: | 1 |
| 20 | Fetal DNA in maternal plasma: a noninvasive tool for prenatal diagnosis of beta- thalassemia显示文摘 | Galbiati S Brisci A Damin F | 2012 | Expert Opin Biol Ther2012,12,1: | 1 |