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| 1 | Update on pathogenesis and predictors of response of therapeutic strategies used in inflammatory bowel disease显示文摘The search for biomarkers that characterize specific aspects of inflammatory bowel disease(IBD), has received substantial interest in the past years and is moving forward rapidly with the help of modern technologies. Nevertheless, there is a direct demand to identify adequate biomarkers for predicting and evaluating therapeutic response to different therapies. In this subset, pharmacogenetics deserves more attention as part of the endeavor to provide personalized medicine. The ultimate goal in this area is the adjustment of medication for a patient's specific genetic background and thereby to improve drug efficacy and safety rates. The aim of the following review is to utilize the latest knowledge on immunopathogenesis of IBD and update the findings on the field of Immunology and Genetics, to evaluate the response to the different therapies. In the present article, more than 400 publications were reviewed but finally 287 included based on design, reproducibility(or expectancy to be reproducible and translationable into humans) or already measured in humans. A few testshave shown clinical applicability. Other, i.e., genetic associations for the different therapies in IBD have not yet shown consistent or robust results. In the close future it is anticipated that this, cellular and genetic material, as well as the determination of biomarkers will be implemented in an integrated molecular diagnostic and prognostic approach to manage IBD patients. | Emilio G Quetglas Zlatan Mujagic Simone Wigge Daniel Keszthelyi Sebastian Wachten Ad Masclee Walter Reinisch | 2015 | World Journal of Gastroenterology2015，21，44： | 3 |
| 2 | Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro显示文摘 | Daniels J T Cambrey AD Occleston NL | 2007 | Invest Ophthalmol Vis Sci2007，48，3： | 1 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy显示文摘 | Daniel J. Klionsky Fabio C. Abdalla Hagai Abeliovich Robert T. Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A. Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizu | 2012 | Autophagy2012，，4： | 1 |
| 4 | Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro显示文摘 | Daniels JT Cambrey AD Occleston NL | | 0，，： | 1 |
| 5 | Toxicities after Radioembolization with Yttrium-90 SIR-Spheres: Incidence and Contributing Risk Factors at a Single Center显示文摘 | Peachy Mae Piana Carin F. Gonsalves Takami Sato P. Rani Anne Jeffrey W. McCann Voichita Bar Ad David J. Eschelman Laurence Parker Laura A. Doyle Daniel B. Brown | 2011 | Journal of Vascular and Interventional Radiology2011，，10： | 1 |
| 6 | Advancing mental tough- ness research and theory using personal construct psychol- ogy显示文摘 | Daniel FG Sandy G James AD | 2009 | International Review of Sport and Exercise Psy- chology2009，2，1： | 1 |
| 7 | Cognitive Function and AllCause Mortality in Maintenance Hemodialysis Patients显示文摘 | David AD Daniel EW Hocine T | 2015 | Am J Kidney Dis2015，65，2： | 1 |
| 8 | Is a 3-mm intrafractional margin sufficient for daily imageguided intensity-modulated radiation therapy of prostate cancer?显示文摘 | Melancon AD O'Daniel JC Zhang LF | 2007 | Radiother Oncol2007，85，： | 1 |
| 9 | Glucagon-Like Peptide-2 Increases Intestinal Lipid Absorption and Chylomicron Production via CD36显示文摘 | Joanne Hsieh Christine Longuet Adriano Maida Jasmine Bahrami Elaine Xu Christopher L. Baker Patricia L. Brubaker Daniel J. Drucker Khosrow Adeli | 2009 | Gastroenterology2009，，3： | 1 |
| 10 | Female urinary, genuine stress incontinence: anatomic considerations at MR imaging of the paravaginal fascia and urethra initial observations 显示文摘 | de Souza NM Daniels OJ Williams AD | 2002 | Radiology2002，225，2： | 1 |
| 11 | Cigarette smoking,steroid hormones and bone mineral density in young women显示文摘 | Daniel M Martin AD Drinkwater DT | 1992 | Calcif Tissue Int1992，50，4： | 1 |
| 12 | Comparison of Multi- IAneage Cells from Human Adipose Tissue and Bone Marrow 显示文摘 | Daniel AD Kouki M Amir E | 2003 | Cells Tissues Organs2003，174，3： | 1 |
| 13 | Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro显示文摘 | Daniels JT Cambrey AD Occleston N Garrett Q Tarnuzzer RW Gregory S | 2003 | Invest Ophthalmol Vis Sci2003，44，3： | 1 |
| 14 | Genetic characterization of Escherichia coli populations from l'ost sources of fecal pollution by using DNA fingerprinting显示文摘 | Mclellan SL Daniels AD Salmore AK | 2003 | Applied and Environmental Microbiology2003，69，： | 1 |
| 15 | Female urinary genuine stress incontinence: anatomic considerations at MR imaging of the paravaginal fascia and urethra initial observations显示文摘 | de Souza NM Daniels OJ Williams AD | 2002 | Radiology2002，225，2： | 1 |
| 16 | IL-8:a Th1-inducing,proinflammatory cytokine and new member of the IL-1 family显示文摘 | Denever MD | 1999 | J Allergy Clin Immunol1999，103，： | 1 |
| 17 | Incidence of microscopic colitis in the Netherlands. A nationwide population-based study from 2000 to 2012显示文摘 | Bas P.M. Verhaegh Daisy M.A.E. Jonkers Ann Driessen Maurice P. Zeegers Daniel Keszthelyi Ad A.M. Masclee Marieke J. Pierik | 2014 | Digestive and Liver Disease2014，，： | 1 |
| 18 | Predictive validity of four bioelectrical impedance equations in determining percent fat mass in overweight and obese children 显示文摘 | Cleary J Daniells S Okely AD | 2008 | J Am Diet Assoc2008，108，1： | 1 |
| 19 | A systematic review of the clinical effectiveness of 64-slice or higher computed tomography angiography as an alternative to invasive coronary angiography in the investigation of suspected coronary artery disease peach and weston BMC cardiovascular显示文摘 | Daniel CP Adèle RW | 2011 | Disorders2011，11，32： | 1 |
| 20 | History and Projection of Hydrological Droughts in the Benin Basin of the Niger River (Benin)显示文摘In the context of a changing climate,the Beninese Niger River basin has been the focus of several research studies for the quantification,planning,and modeling of water and related resources for sustainable use.This research aims to characterize the historical(1976-2019)and projected(2021-2050)hydrological drought of the Beninese Niger River basin.The study used daily observations of rainfall,maximum and minimum temperatures,runoff rates and simulations of HIRHAM and REMO RCMs from fifteen(15)rainfall stations installed around the basin.It uses standardized streamflow indices(SDI)at 12-month and 36-month time steps.The results show that the calculated SDI indices show,on average,for all the model scenarios used,chronological trends of increase.These increases are not significant(are of the order of 0.00001 per year).The analysis of the SDI indices shows that,on average,the hydrological droughts in the Beninese basin of the Niger River will increase at 36 months and decrease at 12 months of the SDI.In fact,these small variations of hydrological droughts will be accompanied by the increase of their duration and the decrease of their magnitudes.The droughts detected in the Benin basin of the Niger River during the historical period will continue until 2050 in the same range but with more extended drought lengths.It should be noted that most of the changes observed in the calculated and analyzed indices are not significant. | Yarou Halissou Alamou Adéchina Eric Biao Iboukoun Eliézer Obada Ezéchiel Tore Daniel Bio Afouda Abel | 2022 | Journal of Atmospheric Science Research2022，5，2： | 0 |
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