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| 1 | Synthesis, antibacterial activities, and pharmacological properties of enantiomers of temalloxacin hydrochloride显示文摘 | Daniel T W Chu Carl W Nordeen Dwight J Hardy et cd | 1991 | J Med Chem1991，34，： | 1 |
| 2 | Isolation of the first piscine transforming growth factor beta gene: analysis reveals tissue specific expression and a potential regulatory sequence in rainbow trout (Oncorhynchus mykiss) 显示文摘 | Hardie L J Laing K J Daniels G D | 1998 | Cytokine1998，10，： | 1 |
| 3 | Cytokines in fish: An update显示文摘 | Secombes C J Hardie L J Daniels G | 1996 | Fish Shellfish Immunol1996，6，4： | 1 |
| 4 | Remote ischemic preconditioning in cyanosed neonates undergoing cardiopulmonary bypass: A randomized controlled trial显示文摘 | Bryn O. Jones Salvatore Pepe Freya L. Sheeran Susan Donath Pollyanna Hardy Lara Shekerdemian Daniel J. Penny Ian McKenzie Stephen Horton Christian P. Brizard Yves d’Udekem Igor E. Konstantinov Michael M.H. Cheung | 2013 | The Journal of Thoracic and Cardiovascular Surgery2013，，： | 1 |
| 5 | Computer-assisted personalized sedation for upper endoscopy and colonoscopy: a comparative, multicenter randomized study显示文摘 | Daniel J. Pambianco John J. Vargo Ronald E. Pruitt Robert Hardi James F. Martin | 2011 | Gastrointestinal Endoscopy2011，，4： | 1 |
| 6 | Cytokines in Fish: An Update 显示文摘 | Secombes C J Hardie L J Daniels G | 1996 | Fish & Shellfish Immunology1996，6，： | 1 |
| 7 | Isolation of the first piscine transforming growth factor beta gene:analysis reveals nitissue specific ex- pression and a potential regulatory sequence in rainbow trout ( Oncorhyn- chus mykiss) 显示文摘 | Hardie L J Laing K J Daniels G D | 1998 | Cytokine1998，10，8： | 1 |
| 8 | Cytokines in fish: an update 显示文摘 | Secombes C J Hardie L J Daniels G | 1996 | Fish Shellfish Immnnol1996，6，： | 1 |
| 9 | Isolation of the first piscine transforming growth factor beta gene:analysis reveals tissue specific expression and a potential regulatory sequence in rainbow trout(Oncorhynchus mykiss)显示文摘 | HARDIE L J LAING K J DANIELS G D | 1998 | Cytokine1998，10，： | 1 |
| 10 | Financial sector liberalization, bank privatization, and efficiency: Evidence from Pakistan显示文摘 | Emilia Bonaccorsi di Patti Daniel C. Hardy | 2005 | Journal of Banking and Finance2005，，8： | 1 |
| 11 | Financial sector liberalization, bank privatization, and efficiency: Evidence from Pakistan显示文摘 | Emilia Bonaccorsi di Patti Daniel C. Hardy | 2005 | Journal of Banking and Finance2005，，8： | 1 |
| 12 | Pilot case study of the therapeutic potential of hyperbaric oxygen therapy on chronic brain injury显示文摘 | Paule Hardy Karen M. Johnston Louis De Beaumont David L. Montgomery Jacqueline M. Lecomte Jean-Paul Soucy Daniel Bourbonnais Maryse Lassonde | 2007 | Journal of the Neurological Sciences2007，，1： | 1 |
| 13 | Hair loss in long-term or home pa- renteral nutrition: are micronutrient deficiencies to blame?显示文摘 | Daniells S Hardy G | 2010 | Curr Opin Clin Nutr Metab Care2010，13，6： | 1 |
| 14 | Remodeling of the plasma for sperm-egg recognition: proteins membrane in preparation roles of acrosomal显示文摘有卵的细胞外的矩阵的精子的相互作用,带 pellucida (ZP ) 是在男、女的配偶子之间的联合的第一个步骤。这个过程的分子的机制被学习过去的六十年了,结果获得了有趣、糊涂。在这篇文章,我们描述我们的最近的工作,它从以前的研究尝试问题的二根线到地址。首先,因为有众多的 ZP,有约束力的蛋白质由各种各样的研究人员报导了,这些蛋白质怎么在 sperm-ZP 一起行动相互作用吗?第二,很多 acrosomal 蛋白质为什么有 ZP 亲密关系?他们主要涉及起始的 sperm-ZP 绑定或相当在抛锚的 acrosome 反应 / 反应精子到 ZP 吗?我们的研究揭示那很多 ZP 有约束力的蛋白质和女伴,从前面的精子头血浆膜提取了,作为高分子的重量(HMW ) 共存建筑群,和那在使能够的精子的这些建筑群有优先的能力绑在 ZP。Zonadhesin (ZAN ) ,与 ZP 亲密关系作为 acrosomal 蛋白质知道,是在 HMW 建筑群的这些蛋白质之一。Immunoprecipitation 显示 ZAN 与另外的 acrosomal 蛋白质, proacrosin/acrosin 和 sp32 (ACRBP ) 交往,在 HMW 建筑群也在场。精子上的 ZAN 和 proacrosin/acrosin 的 Immunodetection 进一步显示到精子头的两蛋白质交通在精子 acrosomal 矩阵仍然是未经触动的 capacitation 期间出现,并且因此,他们多半涉及起始的 sperm-ZP 绑定步。 | Nongnuj Tanphaichitr Kessiri Kongmanas Hathairat Kruevaisayawan Arpornrad Saewu Clarissa Sugeng Jason Fernandes Puneet Souda Jonathan B Angel Kym F Faull R John Aitken Julian Whitelegge Daniel Hardy Trish Berger Mark Baker | 2015 | Asian Journal of Andrology2015，17，4： | 0 |
| 15 | Transaction costs for collaboration in the watershed management of the Cuyahoga River Area of Concern显示文摘This study examines the transaction costs of collaborative watershed management in the Cuyahoga River Area of Concern(AOC)—one of the 43 geographic areas designated by the U.S.and Canada Great Lakes Water Quality Agreement(GLWQA),where significant impairment of beneficial uses has occurred as a result of human activities.The Cuyahoga River is located in Northeast Ohio,the U.S.and flows through the City of Cleveland before draining into Lake Erie—one of the five Great Lakes of North America.The watershed is degraded due to municipal and agricultural discharges,streambank erosion,and contamination from urban and industrial sources.This research explores how a diverse group of stakeholders convened under the Cuyahoga River AOC Advisory Committee to share information,coordinate activities,agree on activities that restore beneficial uses,and support strategic management actions.In this study,23 semi-structured interviews with members of the advisory committee were conducted between January 28,2020 and April 20,2020,with follow-up emails and phone calls as needed to corroborate information.A review of research articles and government documents supported the interviews,including United States Environmental Protection Agency(U.S.EPA)and Ohio Environment Production Agency(OEPA)reports on the GLWQA and Cuyahoga River Remedial Action Plans.A third source of data is from direct participant observation at quarterly meetings of the advisory committee during 2017–2020,binational AOC conferences in 2017 and 2019,and other professional events geared towards restoring the Cuyahoga River AOC in 2016–2020.Results of this study include a set of recommendations to help guide group structure and decision-making processes,including(1)employing best available technology to organize AOC events and disseminate information;(2)supporting new members with an orientation and/or mentor to clearly define formal and informal committee rules;(3)assuring equal access to detailed information on management action plans with a real time dashboard;(4)updating voting procedures and the prioritization of management actions;and(5)better incorporating underrepresented local communities and highlevel decision makers from municipalities,government agencies,and nongovernmental organizations located within the Cuyahoga River AOC.Results help to explain the collaborative process within the advisory committee and measure the institutional performance of the advisory committee in terms of efficiency,equitability,accountability,and adaptability. | Scott Daniel HARDY | 2022 | Regional Sustainability2022，3，2： | 0 |
| 16 | Improved gastrointestinal health for irritable bowel syndrome with metagenome-guided interventions显示文摘Irritable bowel syndrome(IBS)is the most prevalent functional gastrointestinal disorder worldwide,and the most common reason for referral to gastroenterology clinics.However,the pathophysiology is still not fully understood and consequently current management guidelines are very symptom-specific,leading to mixed results.Here we present a study of 88 individuals with IBS who had baseline sequencing of their gut microbiome(stool samples),received targeted interventions that included dietary,supplement,prebiotic/probiotic,and lifestyle recommendations for a 30-day period,and a follow-up sequencing of their gut microbiome.The study’s objectives were to demonstrate unique metagenomic signatures across the IBS phenotypes and to validate whether metagenomic-guided interventions could lead to improvement of symptom scores in individuals with IBS.Enrolled subjects also completed a baseline and post-intervention questionnaire that assessed their symptom scores.The average symptom score of an individual with IBS at baseline was 160 and at the endpoint of the study the average symptom score of the cohort was 100.9.The mixed IBS subtype showed the most significant reduction in symptom scores across the different subtypes(average decrease by 102 points,P=0.005).The metagenomics analysis reveals shifts in the microbiome post-intervention that have been cross-validated with the literature as being associated with improvement of IBS symptoms.Given the complex nature of IBS,further studies with larger sample sizes,more targeted analyses,and a broader population cohort are needed to explore these results further. | Cem Meydan Ebrahim Afshinnekoo Nate Rickard Guy Daniels Laura Kunces Theresa Hardy Loukia Lili Sarah Pesce Paul Jacobson Christopher E.Mason Joel Dudley Bodi Zhang | 2020 | Precision Clinical Medicine2020，3，2： | 0 |
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