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315篇 您的检索式:作者名="Datta G"
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1Absolute copy number differences of Y chromosomal genes between crossbred (Bos taurus×Bos indicus) and Indicine bulls显示文摘Background: The Y chromosome in mammal is paternally inherited and harbors genes related to male fertility and spermatogenesis. The unique intra-chromosomal recombination pattern of Y chromosome and morphological difference of this chromosome between Bos taurus and Bos indicus make it an ideal model for studying structural variation, especially in crossbred(Bos taurus × Bos indicus) bulls. Copy Number Variation(CNV) is a type of genomic structural variation that gives information complementary to SNP data. The purpose of this study was to find out copy number differences of four Y chromosomal spermatogenesis-related candidate genes in genomic DNA of crossbred and purebred Indicine bulls. Result: Four Y chromosomal candidate genes of spermatogenesis namely, sex determining gene on Y chromosome(SRY), DEAD box polypeptide 3-Y chromosome(DDX3Y), Ubiquitin specific peptidase 9, Y-linked(USP9Y), testis-specific protein on Y chromosome(TSPY) were evaluated. Absolute copy numbers of Y chromosomal genes were determined by standard curve-based quantitative real time PCR. Copy numbers of SRY and TSPY genes per unit amount of genomic DNA are higher in crossbred than Indicine bulls. However, no difference was observed in DDX3Y and USP9Y gene copy numbers between two groups. Conclusion: The present study demonstrates that the structural organization of Y chromosomes differs between crossbred and Indicine bulls which are reproductively healthy as observed from analysis of semen attributes. The absolute copy numbers of SRY and TSPY genes in unit mass of genomic DNA of crossbred bulls are significantly higher than Indicine bulls. No alteration in absolute copies of DDX3Y and USP9Y gene was found between the genome of crossbred and Indicine bulls. This study suggests that the DDX3Y and USP9Y are likely to be single copy genes in the genome of crossbred and Indicine bulls and variation in Y chromosome length between crossbred and Indicine bulls may be due to the copy number variation of SRY gene and TSPY array.Ayan Mukherjee Gulshan Dass Jagan Mohanarao G Moloya Gohain Biswajit Brahma Tirtha Kumar Datta Sachinandan De 2013Journal of Animal Science and Biotechnology2013,4,4:3
2JNK1/2 regulates ER-mito- chondrial Ca2+ cross-talk during IL-1β-mediated cell death in RINm5F and human primary β-cells显示文摘Verma G Bhatia H Datta M 2013Mol Biol Cell2013,24,12:1
3New Results on the Synthesis of PID Controllers显示文摘Silva G J Datta A Bhattacharyya S P 2002IEEE Trans on Automatic Control2002,47,2:1
4The molecular basis of sun induced premature skin ageing and retinoid antagonism显示文摘Fisher G J Datta S C Talwar H S 1996Nature1996,379,6563:1
5Isolated microspore derived plant formation via embryogenesis显示文摘Datta S K Wenzel G 1987Plant Sci1987,48,:1
6Arabidopsis CONSTANS-LIKE3 is a positive regulator of red light signaling and root growth显示文摘DATTA S HETTIARACHCHI G H C M DENG X W 2006The Plant Cell Online2006,18,1:1
7Long-term comparison of the agronomic efficiency and residual benefits of organic and inorganic nitrogen sources for tropical lowland rice显示文摘Cassman K G De Datta S K Amarante S T 1996Experimental Agriculture1996,32,:1
8T cell receptor αβ expressing double-negative (CD4- /CD8- ) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis 显示文摘 Tsokos G C Datta S K 1989J Immunol1989,143,:1
9Once-daily insulin glargine versus 6-hour sliding scale regular insulin for control of hyperglycemia after a bariatric surgical procedure: a randomized clinical trial显示文摘Datta SA Qaadir AL Vianueoa G 2007Endocr Pratt2007,3,13:1
10Ameloblasticcarcinoma: report of an aggressive case with multiple bonymetastases 显示文摘Datta R Winston JS Diaz -Reyes G 2003Am J Otolaryngol2003,24,1:1
11Field performance of transgenic elite commercial hybrid rice expressing Bacillus thuringensis endoprotein 显示文摘Tu J Zhang G Datta K 2000Nature BioTechnology2000,18,:1
12Effects of grain refinement and residual elements on hot tearing in aluminum castings 显示文摘KARUNAKAR D B NARESH RAI R A M PATRA S DATTA G L 2009International Journal of Advanced Manufacturing Technology2009,45,:1
13A Fast Trapezoidation Technique for Planar Polygons显示文摘LORENZETTO G P DATTA A THOMAS R C 2002Computer Graphics2002,26,2:1
14Quantum versual classicalcorrelation in Oaussian state显示文摘ADESSO G DATTA A 2010Physical Review Letters2010,105,03:1
15Down-regulation of micro-RNA-1 (miR-1) in lung cancer, suppression of tumor- igenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1 显示文摘NASSER MW DATTA J NUOVO G 2008J Biol Chem2008,283,33:1
16Pathophysiology of premature skin aging induced by ultraviolet light 显示文摘FISHER G J WANG Z Q DATTA S C 1997N Engl J Med1997,337,20:1
17Modification of EPDM with Alkylphenol Polysulfide for Use in Tire Side- walls, 2-Mechanistic and Morphological Characterizations 显示文摘Zhang H M Datta R N Talma A G 2010Macromolecular Materials and Engineering2010,295,1:1
18ApoE mimetic peptide re- duces plasma lipid hydroperoxide content with a concomitant in- crease in HDL paraoxonase activity显示文摘Datta G Chaddha M Handattu SP 2010Adv Exp Med Biol2010,660,1:1
19Pathophysiology of premature skin aging induced by ultraviolet light显示文摘Fisher G J Wang Zeng-quan Datta S C 0,,20:1
20Field performance of trans- genic elite commercial hybrid rice expressing Bacillus thuringiensis 3--endotoxin显示文摘TU J ZHANG G DATTA K 2000Nature Biotechnology2000,18,10:1
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