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| 1 | Metabolic responses of Eucalyptus species to different temperature regimes显示文摘Species and hybrids of Eucalyptus are the world's most widely planted hardwood trees. They are cultivated across a wide range of latitudes and therefore environmental conditions. In this context, comprehensive metabolomics approaches have been used to assess how different temperature regimes may affect the metabolism of three species of Eucalyptus, E. dunnii, E. grandis and E. pellita.Young plants were grown for 53 d in the greenhouse and then transferred to growth chambers at 10°C, 20°C or30°C for another 7 d. In all three species the leaf chlorophyll content was positively correlated to temperature, and in E.pellita the highest temperature also resulted in a significant increase in stem biomass. Comprehensive metabolomics was performed using untargeted gas chromatography mass spectrometry(GC-MS) and liquid chromatography(LC)-MS.This approach enabled the comparison of the relativeabundance of 88 polar primary metabolites from GC-MS and625 semi-polar secondary metabolites from LC-MS. Using principal components analysis, a major effect of temperature was observed in each species which was larger than that resulting from the genetic background. Compounds mostly affected by temperature treatment were subsequently selected using partial least squares discriminant analysis and were further identified. These putative annotations indicated that soluble sugars and several polyphenols, including tannins, triterpenes and alkaloids were mostly influenced. | Joao Benhur Mokochinski Paulo Mazzafera Alexandra Christine Helena Frankland Sawaya Roland Mumm Ric Cornelis Hendricus de Vos Robert David Hall | 2018 | Journal of Integrative Plant Biology2018，60，5： | 2 |
| 2 | Lithostratigraphy,Sedimentology,and Provenance of the Balfour Formation(Beaufort Group) in the Fort Beaufort-Alice Area,Eastern Cape Province,South Africa显示文摘The Balfour Formation was subdivided into five members based on lithological variation that is characterized by alternating sandstone-and mudstone -dominated members.The sandstone dominated Oudeberg and Barberskrans members are composed of lithofacies that range from intraformational conglomerates to fine-grained sediments,whereas the mudstone dominated members(Daggaboersnek, Elandsberg and Palingkloof) are dominated by the fine-grained facies(Fm and F1).Petrography,geochemistry and palaeocurrent analysis indicated that the source rock of the Balfour Formation was to | David KATEMAUNZANGA Cornelis Janse GUNTER | 2009 | Acta Geologica Sinica(English Edition)2009，83，5： | 1 |
| 3 | Early spontaneous intermittent myocardial reperfusion during acute myocardial infarction is associated with augmented thrombogenic activity and less myocardial damage显示文摘 | Agha W. Haider Felicita Andreotti David R. Hackett Dimitris Tousoulis Cornelis Kluft Attilio Maseri Graham J. Davies | 1995 | Journal of the American College of Cardiology1995，，3： | 1 |
| 4 | Specific Temporal Profile of Matrix Metalloproteinase Release Occurs in Patients After Myocardial Infarction: Relation to Left Ventricular Remodeling显示文摘 | Carson S. Webb David D. Bonnema S Hinan Ahmed Amy H. Leonardi Catherine D. McClure Leslie L. Clark Robert E. Stroud William C. Corn Laura Finklea Michael R. Zile Francis G. Spinale | 2006 | Circulation2006，，10： | 1 |
| 5 | A novel method for insertion of post-pyloric feeding tubes at the bedside without endoscopic or fluoroscopic assistance: a prospective study显示文摘 | Cornelis Slagt Richard Innes David Bihari John Lawrence Yahya Shehabi | 2004 | Intensive Care Medicine2004，，1： | 1 |
| 6 | Properties of an adaptive archiving algorithm for storing nondominated vectors显示文摘 | Joshua Knowles David Corne | 2003 | IEEE Trans on Evolutionary Computation2003，7，2： | 1 |
| 7 | A large benchmark dataset for web document clustering显示文摘 | Mark Sinka David Corne | 2002 | In Soft Computing Systems:Design Management and Applications Frontiers in Artificial Intelligence and Applications2002，2002，87： | 1 |
| 8 | Benefit segmentation for industrial products显示文摘 | Cornelis A De Kluyver David B Whitlark | 1986 | Industrial Marketing Management1986，15，4： | 1 |
| 9 | Multidisciplinary Rectal Cancer Management: 2nd European Rectal Cancer Consensus Conference (EURECA-CC2)显示文摘 | Vincenzo Valentini Cynthia Aristei Bengt Glimelius Bruce D. Minsky Regina Beets-Tan Jose M. Borras Karin Haustermans Philippe Maingon Jens Overgaard Lars Pahlman Phil Quirke Hans-Joachim Schmoll David Sebag-Montefiore Irving Taylor Eric Van Cutsem Corneli | 2009 | Radiotherapy and Oncology2009，，2： | 1 |
| 10 | 采用分析方法、毒理学和风险评估研究评估多环芳烃:以石油泄漏后海产品安全为案例显示文摘[背景]多环芳香烃(PAHs)是一种大量蔓延的环境化学物质。它们可通过自然和人为过程产生,通常存在于有机介质(包括石油)中。有几种PAHs是有毒的,其中一些还表现出致癌活性。PAHs以含有两个及以上苯环的一系列化学结构为特征,根据它们的来源,可以通过氧化、氮化和烷基化表现出多种侧链修饰。[目的]讨论当代分析方法日益增加的能力,其不仅可以分辨PAHs中不同的化学结构,而且可以识别它们在环境介质中的浓度。本文以深水地平线事故后海产品污染为例,确定由于个别PAHs的分析灵敏度增加而在PAHs风险评估过程中出现的一些问题,并描述其中许多化合物的毒理学文献缺乏的现状。[讨论]PAHs,包括种类繁多的经化学修饰或取代的PAHs,是自然产生的,如果人群暴露于有害水平就可能会遭受健康风险。然而,目前的毒性评估并没有跟上现代分析方法及其对于被替代的PAHs不断增加的检测能力。因此,尽管我们可以在海产品和其他媒介中检测这些化合物,但并没有足够的关于这些化合物的潜在毒性信息,无法将它们用于人类健康风险评估和特征描述。[结论]今后的研究工作应该尝试从战略上填补这一毒理学知识欠缺,从而更好地进行环境介质或食物中关于PAHs的人体健康风险评估。这对于石油泄漏之后的影响尤为重要。 | Jeffrey Wickliffe Edward Overton Scott Frickel Jessi Howard Mark Wilson Bridget Simon Stephen Echsner Daniel Nguyen David Gauthe Diane Blake Charles Miller Cornelis Elferink Shakeel Ansari Harshica Ferno Edward Trapido Andrew Kane 张晶 汪源 金泰廙 | 2014 | 环境与职业医学2014，31，6： | 1 |
| 11 | Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging显示文摘 | Gudmundur L. Norddahl Cornelis J. Pronk Martin Wahlestedt Gerd Sten Jens M. Nygren Amol Ugale Mikael Sigvardsson David Bryder | 2011 | Cell Stem Cell2011，，5： | 1 |
| 12 | Curative Treatment of Stage I Non-Small-Cell Lung Cancer in Patients With Severe COPD: Stereotactic Radiotherapy Outcomes and Systematic Review显示文摘 | David Palma Frank Lagerwaard George Rodrigues Cornelis Haasbeek Suresh Senan | 2012 | International Journal of Radiation Oncology, Biology, Physics2012，，3： | 1 |
| 13 | A novel method for insertion of post-pyloric feeding tubes at the bedside without endoscopic or fluoroscopic assistance: a prospective study显示文摘 | Cornelis Slagt Richard Innes David Bihari John Lawrence Yahya Shehabi | 2004 | Intensive Care Medicine2004，，1： | 1 |
| 14 | Preoperative chemo(radio)therapy versus primary surgery for gastroesophageal adenocarcinoma: Systematic review with meta-analysis combining individual patient and aggregate data显示文摘 | Ulrich Ronellenfitsch Matthias Schwarzbach Ralf Hofheinz Peter Kienle Meinhard Kieser Tracy E. Slanger Bryan Burmeister David Kelsen Donna Niedzwiecki Christoph Schuhmacher Susan Urba Cornelis van de Velde Thomas N. Walsh Marc Ychou Katrin Jensen | 2013 | European Journal of Cancer2013，，： | 1 |
| 15 | Induced Systemic Resistance by Beneficial Microbes显示文摘 | Corné M.J. Pieterse Christos Zamioudis Roeland L. Berendsen David M. Weller Saskia C.M. Van Wees Peter A.H.M. Bakker | 2014 | Annual Review of Phytopathology2014，，： | 1 |
| 16 | Withholding stereotactic radiotherapy in elderly patients with stage I non-small cell lung cancer and co-existing COPD is not justified: Outcomes of a markov model analysis显示文摘 | Alexander V. Louie George Rodrigues Malek Hannouf Frank Lagerwaard David Palma Gregory S. Zaric Cornelis Haasbeek Suresh Senan | 2011 | Radiotherapy and Oncology2011，，2： | 1 |
| 17 | Establishment of a geographic data dictionary: a case study of UrbIS 2 ? , the Brussels regional government GIS显示文摘 | Dimos Pantazis Bernard Cornélis Roland Billen David Sheeren | 2001 | Computers Environment and Urban Systems2001，，1： | 1 |
| 18 | VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis显示文摘 | Lukas J.A.C. Hawinkels Kim Zuidwijk Hein W. Verspaget Eveline S.M. de Jonge-Muller Wim van Duijn Valérie Ferreira Ruud D. Fontijn Guido David Daniel W. Hommes Cornelis B.H.W. Lamers Cornelis F.M. Sier | 2008 | European Journal of Cancer2008，，13： | 1 |
| 19 | Multidisciplinary Rectal Cancer Management: 2nd European Rectal Cancer Consensus Conference (EURECA-CC2)显示文摘 | Vincenzo Valentini Cynthia Aristei Bengt Glimelius Bruce D. Minsky Regina Beets-Tan Jose M. Borras Karin Haustermans Philippe Maingon Jens Overgaard Lars Pahlman Phil Quirke Hans-Joachim Schmoll David Sebag-Montefiore Irving Taylor Eric Van Cutsem Corneli | 2009 | Radiotherapy and Oncology2009，，2： | 1 |
| 20 | Brain Iron Toxicity: Differential Responses of Astrocytes, Neurons, and Endothelial Cells显示文摘 | Julie A. Gaasch Paul R. Lockman Werner J. Geldenhuys David D. Allen Cornelis J. Schyf | 2007 | Neurochemical Research2007，，7： | 1 |
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