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| 1 | Perfusion magnetic resonance imaging of the liver显示文摘Perfusion magnetic resonance imaging (MRI) studies quantify the microcirculatory status of liver parenchyma and liver lesions, and can be used for the detection of liver metastases, assessing the effectiveness of antiangiogenic therapy, evaluating tumor viability after anticancer therapy or ablation, and diagnosis of liver cirrhosis and its severity. In this review, we discuss the basic concepts of perfusion MRI using tracer kinetic modeling, the common kinetic models applied for analyses, the MR scanning techniques, methods of data processing, and evidence that supports its use from published clinical and research studies. Technical standardization and further studies will help to establish and validate perfusion MRI as a clinical imaging modality. | Choon Hua Thng Tong San Koh David J Collins Dow Mu Koh | 2010 | World Journal of Gastroenterology2010,16,13: | 15 |
| 2 | 针对患者利益的机器学习和人工智能研究:在透明性、可重复性、伦理和有效性等方面的20个关键问题显示文摘机器学习(ML)、人工智能(AI)和其他现代统计方法正为利用先前尚未开发且极速增长的数据资源提供新的机会,以期让患者获益。尽管目前正在进行许多有前景的研究,特别是在图像方面,但就文献整体而言还缺乏透明度、对可重复性清晰的阐述、对潜在伦理问题的探究,以及对有效性的明确验证。这些问题的存在有许多原因,其中最重要的一点(为此我们提供了初步解决方案)就是当前缺乏针对ML和AI的最佳实践指南。我们认为从事研究的跨学科团队和应用ML/AI影响健康的项目,将因解决有关透明度、可重复性、伦理和有效性(TREE)的一系列问题而受益。这里提出的20个关键问题为研究团队提供了一个研究设计、实施和报告框架;帮助编辑和同行评审专家评估文献的贡献;让患者、临床医生和政策制定者评估新发现可能会给患者带来的获益。 | Sebastian Vollmer Bilal A Mateen Gergo Bohner Franz J Kirdly Rayid Ghani Pall Jonsson Sarah Cumbers Adrian Jonas Katherine S L McAllister Puja Myles David Granger Mark Birse Richard Branson Karel G M Moons Gary S Collins John P A Chris Holmes Harry Hemingwayp 李峰(译) 徐磊(校) 赵邑(校) | 2020 | 英国医学杂志中文版2020,23,9: | 5 |
| 3 | Ruptured synthetic expanded polytertrafluoroethylene chordae tendinae 显示文摘 | Butany J Collins MJ David TE | 2004 | Cardiovasc Pathol2004,13,3: | 1 |
| 4 | Biochar: A Synthesis of Its Agronomic Impact beyond Carbon Sequestration显示文摘 | Spokas Kurt A Cantrell Keri B M Novak Jeffrey Archer David W Ippolito James A Collins Harold P Boateng Akwasi A Lima Isabel M Lamb Marshall C McAloon Andrew J Lentz Rodrick D Nichols Kristine A | 2012 | Journal of Environmental Quality2012,,4: | 1 |
| 5 | Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10显示文摘 | A. Elisabeth Karlbom C. David James Jürgen Boethius Webster K. Cavenee V. Peter Collins Magnus Nordenskj?ld Catharina Larsson | 1993 | Human Genetics1993,,2: | 1 |
| 6 | Diffusion-weighted MRI in the body:applications and challenges in oncology显示文摘 | Koh DM Collins DJ David J | 2007 | AJR Am J Roentgenol2007,188,6: | 1 |
| 7 | Triaxial inertial switch with multiple thresholds and resis- tive ladder readout显示文摘 | Luke J Currano Collin R Becker David Lunking | 2012 | Sensors and Actuators A: Physi- cal2012,29,6: | 1 |
| 8 | The reaction of 1,8 -diazabicyclo undec- 7 -ene (DBU) with carbon dioxide显示文摘 | DAVID J HELDEBRANT PHILIP G JESSOP COLLIN A THOMAS | 2005 | J Org Chem2005,70,: | 1 |
| 9 | New tools for management of phosphine resistance显示文摘 | DAVID SCHLIPALIUS COLLINS PATRICK J YOSEP MAU | 2006 | Outlooks on Pest Management2006,3,: | 1 |
| 10 | Competing on Resources:Strategy in the 1990s显示文摘 | Collins David J Montgomery Cynthia | | 0,,04: | 1 |
| 11 | Biochar: A Synthesis of Its Agronomic Impact beyond Carbon Sequestration显示文摘 | Spokas Kurt A Cantrell Keri B M Novak Jeffrey Archer David W Ippolito James A Collins Harold P Boateng Akwasi A Lima Isabel M Lamb Marshall C McAloon Andrew J Lentz Rodrick D Nichols Kristine A | 2012 | Journal of Environmental Quality2012,,4: | 1 |
| 12 | Constructivism and Computer-Mediated Communication in Distance Education显示文摘 | Collins M Compbell J | 1995 | The American Journal of Distance Education1995,9,2: | 1 |
| 13 | 禽流感病毒H5N1血凝素蛋白的细胞膜上提纯和结晶显示文摘目的从细胞膜上提纯禽流感病毒H5N1的血凝素蛋白H51151F和H51151F+A134V+E186D,并使蛋白结晶。方法细胞内大量增殖重组牛痘病毒,去垢剂提取细胞膜中的HA蛋白,连续蔗糖密度梯度超速离心,Western印迹检测,菠萝蛋白酶等裂解HA,离子交换层析,SDS—PAGE电泳并染色检测蛋白纯度,坐滴气象扩散法结晶。结果从细胞膜中提取了高纯度的血凝素蛋白H51151F和H51151F+A134V+E186D,并得到了H51151F蛋白晶体。结论首次获得了禽流感病毒H5N1的I-IS1151F蛋白晶体,为进一步研究禽流感病毒人传人的可能性打下基础。 | 谌资 郑煜煌 Yipu Lin David J Stevens Steve A Wharton Patrick J Collins Junfeng Liu Alan J Hay | 2009 | 中国医师杂志2009,11,5: | 0 |
| 14 | Resolution of Crohn's disease and complex regional pain syndrome following treatment of paratuberculosis显示文摘A cohort of family members with various chronic diseases including Crohn's disease, asthma, complex regional pain syndrome, hypothyroidism, type 1 diabetes mellitus, and lymphangiomatosis and/or evidence of infection by Mycobacterium avium subsp. paratuberculosis(MAP) are described in this series of case reports. MAP was cultured from the blood of three members affected by the first five diseases and there was accompanying elevated anti-MAP Ig G in two members. The patient affected by the sixth disease has a markedly elevated anti-MAP titer. The two patients affected by the first four diseases have been treated with a combination of anti-MAP antibiotics and ultraviolet blood irradiation therapy with resolution of the disease symptomatology and inability to culture MAP in post treatment blood samples. These case reports of patients with MAP infections provide supportive evidence of a pathogenic role of MAP in humans. | J Todd Kuenstner William Chamberlin Saleh A Naser Michael T Collins Coad Thomas Dow John M Aitken Stuart Weg Grzegorz Telega Kuruvilla John David Haas Torsten M Eckstein Maher Kali Christine Welch Thomas Petrie | 2015 | World Journal of Gastroenterology2015,21,13: | 0 |