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| 1 | 与在人的疾病的糖尿病 mellitus 和肥胖有关的肾的 hyperfiltration显示文摘 High intraglomerular pressure is associated with renal hyperf iltration, leading to the initiation and progression of kidney disease in experimental models of diabetes mellitus (DM). In humans, hyperf iltration is observed in patients with type 1 and type 2 DM, and is also seen in patients with pre-diabetic conditions, such as the metabolic syndrome. From a mechanistic perspective, both vascular and tubular factors likely contribute to the pathogenesis of hyperf iltration. Until now, human studies have primarily focused on the use of medications that inhibit the renin angiotensin system to reduce efferent vasoconstriction and thereby improve hyperfiltration. More recent advances in the development of investigational adenosine antagonists and inhibitors of sodium glucose cotransport may help to elucidate tubular factors that contribute to afferent vasodilatation. In this review, we summarize available data from experimental and human studies of type 1 and type 2 DM and obesity to provide an overview of factors that contribute to the hyperf iltration state. We have focused on the renin angiotensin system, cyclooxygenase-2 system, nitric oxide, protein kinase C and endothelin as vascular determinants of hyperfiltration. We also dis-cuss relevant tubular factors, since experimental models have suggested that inhibition of sodium-glucose cotransport may be renoprotective. | Alexa N Sasson David ZI Cherney | 2012 | World Journal of Diabetes2012,3,1: | 11 |
| 2 | Insulating materials for realising carbon neutrality:Opportunities,remaining issues and challenges显示文摘The 2050 carbon-neutral vision spawns a novel energy structure revolution,and the construction of the future energy structure is based on equipment innovation.Insulating material,as the core of electrical power equipment and electrified transportation asset,faces unprecedented challenges and opportunities.The goal of carbon neutral and the urgent need for innovation in electric power equipment and electrification assets are first discussed.The engineering challenges constrained by the insulation system in future electric power equipment/devices and electrified transportation assets are investigated.Insulating materials,including intelligent insulating material,high thermal conductivity insulating material,high energy storage density insulating material,extreme environment resistant insulating material,and environmental-friendly insulating material,are cat-egorised with their scientific issues,opportunities and challenges under the goal of carbon neutrality being discussed.In the context of carbon neutrality,not only improves the understanding of the insulation problems from a macro level,that is,electrical power equipment and electrified transportation asset,but also offers opportunities,remaining issues and challenges from the insulating material level.It is hoped that this paper en-visions the challenges regarding design and reliability of insulations in electrical equipment and electric vehicles in the context of policies towards carbon neutrality rules.The authors also hope that this paper can be helpful in future development and research of novel insulating materials,which promote the realisation of the carbon-neutral vision. | Chuanyang Li Yang Yang Guoqiang Xu Yao Zhou Mengshuo Jia Shaolong Zhong Yu Gao Chanyeop Park Qiang Liu Yalin Wang Shakeel Akram Xiaoliang Zeng Yi Li Fangwei Liang Bin Cui Junpeng Fang Lingling Tang Yulin Zeng Xingtao Hu Jiachen Gao Giovanni Mazzanti Jinliang He Jianxiao Wang Davide Fabiani Gilbert Teyssedre Yang Cao Feipeng Wang Yunlong Zi | 2022 | High Voltage2022,7,4: | 4 |
| 3 | Comparison of Frontier Efficiency Methods: An Application to the U.S. Life Insurance Industry显示文摘 | J. David Cummins Hongmin Zi | 1998 | Journal of Productivity Analysis1998,,2: | 1 |
| 4 | Synthesis, Structure and Magnetic Properties of Novel Carboxylato-bridged Pentanuclear Copper(Ⅱ)-Lanthanoid(Ⅲ) Complexes显示文摘IntroductionPolynuclearmixed-metalcomplexescontainingbothtransitionandlanthanoidmetalionsareofspecialcurentinterestinrelation... | TONG Ming liang, WU Yu luan and CHEN Xiao ming ** (Department of Chemistry, Zhongshan University, Guangzhou, 510275) SUN Zi ming and David N. Hendrickson ** (Department of Chemistry 0358, University of California at San Diego, La Jol | 1998 | Chemical Research in Chinese Universities1998,14,3: | 1 |
| 5 | Economies of scope in financial services: A DEA efficiency analysis of the US insurance industry显示文摘 | J. David Cummins Mary A. Weiss Xiaoying Xie Hongmin Zi | 2010 | Journal of Banking and Finance2010,,7: | 1 |
| 6 | Sodium-Glucose Cotransporter 2 Inhibition and Glycemic Control in Type 1 Diabetes: Results of an 8-Week Open-Label Proof-of-Concept Trial显示文摘 | Perkins Bruce A Cherney David ZI Partridge Helen Soleymanlou Nima Tschirhart Holly Zinman Bernard Fagan Nora M Kaspers Stefan Woerle Hans-Juergen Broedl Uli C Johansen Odd-Erik | 2014 | Diabetes Care2014,,5: | 1 |
| 7 | Enteric Neuronal Density Contributes to the Severity of Intestinal Inflammation显示文摘 | Kara Gross Margolis Korey Stevanovic Nima Karamooz Zi Shan Li Ankur Ahuja Fabien D’Autréaux Virginia Saurman Alcmene Chalazonitis Michael David Gershon | 2011 | Gastroenterology2011,,2: | 1 |
| 8 | A mechanistic model for the photosynthesis - light response based on the photosynthetic electron transport of photosystem Ⅱ in C3 and C4species显示文摘 | YE ZI PIAO DAVID J S PIOTR R | 2013 | NewPhytotogist2013,199,1: | 1 |
| 9 | The Growth and feeding patternd of 9 to 12 moths old Chinese Canadian infant显示文摘 | Christina Sit David L Yeung Mei Zi He | 2001 | Nutrition Research2001,21,: | 1 |
| 10 | The an- giotensin ]I receptor type 2 polymorphism influences haemodynamic function and circulating RAS mediators in normotensive humans显示文摘 | David ZI Cherney Vesta Lai Judith A | 2010 | Nephrology Dialysis Transplan- tation: Official Publication of the European Dialysis and Transplant Association-European Renal Association2010,25,12: | 1 |
| 11 | Comparison of Frontier Efficiency Methods: An Application to the U.S. Life Insurance Industry显示文摘 | J. David Cummins Hongmin Zi | 1998 | Journal of Productivity Analysis1998,,2: | 1 |
| 12 | Tantalum pentoxide:a new material platform for high-performance dielectric metasurface optics in the ultraviolet and visible region显示文摘Dielectric metasurfaces,composed of planar arrays of subwavelength dielectric structures that collectively mimic the operation of conventional bulk optical elements,have revolutionized the field of optics by their potential in constructing high-efficiency and multi-functional optoelectronic systems on chip.The performance of a dielectric metasurface is largely determined by its constituent material,which is highly desired to have a high refractive index,low optical loss and wide bandgap,and at the same time,be fabrication friendly.Here,we present a new material platform based on tantalum pentoxide(Ta2O5)for implementing high-performance dielectric metasurface optics over the ultraviolet and visible spectral region.This wide-bandgap dielectric,exhibiting a high refractive index exceeding 2.1 and negligible extinction coefficient across a broad spectrum,can be easily deposited over large areas with good quality using straightforward physical vapor deposition,and patterned into high-aspect-ratio subwavelength nanostructures through commonly-available fluorine-gas-based reactive ion etching.We implement a series of highefficiency ultraviolet and visible metasurfaces with representative light-field modulation functionalities including polarization-independent high-numerical-aperture lensing,spin-selective hologram projection,and vivid structural color generation,and the devices exhibit operational efficiencies up to 80%.Our work overcomes limitations faced by scalability of commonly-employed metasurface dielectrics and their operation into the visible and ultraviolet spectral range,and provides a novel route towards realization of high-performance,robust and foundry-manufacturable metasurface optics. | Cheng Zhang Lu Chen Zhelin Lin Junyeob Song Danyan Wang Moxin Li Okan Koksal Zi Wang Grisha Spektor David Carlson Henri J.Lezec Wenqi Zhu Scott Papp Amit Agrawal | 2024 | Light(Science & Applications)2024,13,1: | 0 |
| 13 | Advanced insulating materials contributing to“carbon neutrality”:Opportunities,issues and challenges显示文摘The vision of 2050 worldwide carbon-neutral ignites a revo-lution in all industries.Enormous innovations in both electrical power equipment and electrified transportation assets are shaping our future energy structure.Insulating materials,as the core element of energy infrastructure,are facing unprece-dented challenges that stand in the pathways to global carbon neutrality.However,researchers from both academic in-stitutions and industrial sections are working to turn the challenges into opportunities. | Chuanyang Li Yunlong Zi Yang Cao Giovanni Mazzanti Davide Fabiani Di Zhang Yunqi Xing Jinliang He | 2022 | High Voltage2022,7,4: | 0 |