|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Inheritance and population structure of the white-phased 'Kermode' black bear显示文摘 | KERMIT R CRAIG N H DAWN M | 2001 | Current Biology2001，18，11： | 1 |
| 2 | 多普勒超声扫描、磁共振血管造影和CT血管造影用于症状性下肢动脉疾病的诊断和评估:系统性综述显示文摘目的探讨多普勒超声扫描、磁共振血管造影和 CT 血管造影单独或联合应用在评估下肢动脉疾病中的诊断准确性;评价这些检查方法对患者治疗和结果的影响;评价患者对这些检查方法的态度并总结与不良事件相关的现有资料。设计系统性综述。方法检索11个电子数据库(截至2005年4月)、6本杂志和已找到文献中的参考文献以发现相关研究。两名评审员独立选择研究、提取资料和评估质量。使用 QUADASQ 目录评估诊断准确性研究的质量。结果 107项研究符合入选标准;其中,58项研究提供关于诊断准确性的资料,1项关于患者结果,4项关于患者态度和44项关于不良事件。质量评估强调研究报告的方法及质量的不足。由于大多数入选研究根据动脉节段而不是整条肢体或患者来报告结果,这样就不能解释患者多节段病变,所以可能高估检查的特异度。对发现下肢动脉50%及以上狭窄,造影剂增强磁共振血管造影诊断准确性最高,敏感度中位数95%(92%~99.5%)和特异度中位数97%(64%~99%);CT 血管造影分别为91%(89%~99%)和91%(83%~97%);多普勒超声扫描为88%(80%~98%)和96%(89%~99%)。一项对照试验报告,尽管基于单一的多普勒超声扫描或传统血管造影患者的治疗结果无明显差异,但是22%的患者需要另行血管造影以制定治疗方案。现有的证据表明:相对于传统血管造影,患者更愿意选择磁共振血管造影(有或无造影剂增强),而在磁共振血管造影无禁忌(如患有幽居恐怖症)的患者中,半数对磁共振血管造影或多普勒超声扫描无偏好。在现有关于不良事件的资料中,磁共振血管造影发生不良事件的比例最高,但是症状轻微。最严重的不良事件,尽管少见,但主要发生于传统血管造影中。结论造影剂增强磁共振血管造影较 CT 血管造影特异性更高(排除50%以上狭窄病变的准确性更高),较多普勒超声扫描敏感性更强(诊断50%以上狭窄病变的准确性更强);相对于传统血管造影,患者一般更愿意选择造影剂增强磁共振血管造影。另外,与传统血管造影相比,患者还愿意选择 CT 血管造影。患者对多普勒超声扫描和传统血管造影的偏好尚无资料。现有资料表明,造影剂增强磁共振血管造影可能是替代血管造影的一种有前景的检查手段。 | Ros Collins Jane Burch Gillian Cranny Raquel Aguiar-Ibáez Dawn Craig Kath Wright Elizabeth Berry Michael Gough Jos Kleijnen Marie Westwood 施德兵 | 2007 | 英国医学杂志中文版2007，10，6： | 1 |
| 3 | Understanding consumer in- terest in product and process - based attributes for fresh produce 显示文摘 | Craig A B Dawn T Jennifer K B | 2008 | Agribusiness2008，24，2： | 1 |
| 4 | A 24 hour naproxen dose on gastrointestinal distress and performance during cycling in the heat显示文摘Using a double-blind,randomized and counterbalanced,cross-over design,we assessed naproxen's effects on gastrointestinal(GI)distress and performance in eleven volunteers(6 male,5 female).Participants completed 4 trials:1)placebo and ambient);2)placebo and heat;3)naproxen and ambient;and 4)naproxen and heat.Independent variables were one placebo or 220 mg naproxen pill every 8 h(h)for 24 h and ambient(22.7±1.8℃)or thermal environment(35.7±1.3℃).Participants cycled 80 min at a steady heart rate then 10 min for maximum distance.Perceived exertion was measured throughout cycling.Gastrointestinal distress was assessed pre-,during,post-,3 h post-,and 24 h post-cycling using a GI index for upper,lower,and systemic symptoms.No statistically significant differences occurred between conditions at any time for GI symptoms or perceived exertion,distance,or heart rate during maximum effort.A 24 h naproxen dose did not significantly affect performance or cause more frequent or serious GI distress when participants were euhydrated and cycling at moderate intensity in a thermal environment. | Dawn M.Emerson J.Mark Davis Stephen CL.Chen Toni M.Torres-McGehee Craig E.Pfeifer Charles C.Emerson Joseph D.Bivona Justin V.Stone | 2020 | Sports Medicine and Health Science2020，2，1： | 0 |
| 5 | An acute naproxen dose does not affect core temperature or Interleukin-6 during cycling in a hot environment显示文摘Non-steroidal anti-inflammatory drugs’anti-pyretic and anti-inflammatory effects has led some individuals to theorize these medications may blunt core body temperature(Tc)increases during exercise.We utilized a double-blind,randomized,and counterbalanced cross-over design to examine the effects of a 24-h naproxen dose(3–220 mg naproxen pills)and placebo(0 mg naproxen)on Tc and plasma interleukin-6(IL-6)concentrations during cycling in a hot or ambient environment.Participants(n=11;6 male,5 female;age=27.8±6.5 years,weight=79.1±17.9 kg,height=177±9.5 cm)completed 4 conditions:1)placebo and ambient(Control);2)placebo and heat(Heat);3)naproxen and ambient(Npx);and 4)naproxen and heat(NpxHeat).Dependent measures were taken before,during,and immediately after 90 min of cycling and then 3 h after cycling.Overall,Tc significantly increased pre-(37.1±0.4℃)to post-cycling(38.2±0.3℃,F_(1.7,67.3)=150.5,p<0.001)and decreased during rest(37.0±0.3℃,F_(2.0,81.5)=201.6,p<0.001).Rate of change or maximum Tc were not significantly different between conditions.IL-6 increased pre-(0.54±0.06 pg/ml)to post-exercise(2.46±0.28 pg/ml,p<0.001)and remained significantly higher than pre-at 3 h post-(1.17±0.14 pg/ml,95%CI=-1.01 to-0.23,p=0.001).No significant IL-6 differences occurred between conditions.A 24-h,over-the-counter naproxen dose did not significantly affect Tc or IL-6 among males and females cycling in hot or ambient environments. | Dawn M.Emerson Stephen CL.Chen Toni M.Torres-McGehee Craig E.Pfeifer Charles C.Emerson J.Mark Davis | 2021 | Sports Medicine and Health Science2021，3，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员