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| 1 | Laparoscopic natural orifice specimen extraction-colectomy: A systematic review显示文摘Over the last 20 years, laparoscopic colorectal surgery has shown equal efficacy for benign and malignant colorectal diseases when compared to open surgery. However, a laparoscopic approach reduces postoperative morbidity and shortens hospital stay. In the quest to optimize outcomes after laparoscopic colorectal surgery, reduction of access trauma could be a way to improve recovery. To date, one method to reduce access trauma is natural orifice specimen extraction(NOSE). NOSE aims to reduce access trauma in laparoscopic colorectal surgery. The specimen is delivered via a natural orifice and the anastomosis is created intracorporeally. Different methods are used to extract the specimen and to create a bowel anastomosis. Currently, specimens are delivered transcolonically, transrectally, transanally, or transvaginally. Each of these NOSEprocedures raises specific issues with regard to operative technique and application. The presumed benefits of NOSE-procedures are less pain, lower analgesia requirements, faster recovery, shorter hospital stay, better cosmetic results, and lower incisional hernia rates. Avoidance of extraction site laparotomy is the most important characteristic of NOSE. Concerns associated with the NOSE-technique include bacterial contamination of the peritoneal cavity, inflammatory response, and postoperative outcomes, including postoperative pain and the functional and oncologic outcomes. These issues need to be studied in prospective randomized controlled trials. The aim of this systematic review is to describe the role of NOSE in minimally invasive colorectal surgery. | Albert M Wolthuis Anthony de Buck van Overstraeten André D'Hoore | 2014 | World Journal of Gastroenterology2014，20，36： | 65 |
| 2 | Transanal total mesorectal excision:Towards standardization of technique显示文摘AIM: To describe the role of Transanal total mesorectal excision(Ta TME) in minimally invasive rectal cancer surgery, to examine the differences in patient selection and in reported surgical techniques and their impactson postoperative outcomes and to discuss the future of Ta TME. METHODS: MEDLINE(Pub Med), EMBASE, and The Cochrane Library were systematically searched through the 1st of March 2015 using a predefined search strategy. RESULTS: A total of 20 studies with 323 patients were included. Most studies were single-arm prospective studies with fewer than 100 patients. Multiple transanal access platforms were used, and the laparoscopic approach was either multi- or single port. The procedure was initiated transanally or transabdominally. If a simultaneous approach with 2 operating surgeons was chosen, the operative time was significantly reduced. CONCLUSION: Ta TME was also associated with better TME specimens and a longer distal resection margin. Ta TME is thus feasible in expert hands, but the learning curve and safety profile are not well defined. Longterm follow-up regarding anal function and oncological outcomes should be performed in the future. | Albert M Wolthuis Gabriele Bislenghi Anthony de Buck van Overstraeten André D'Hoore | 2015 | World Journal of Gastroenterology2015，21，44： | 9 |
| 3 | Surgery for Crohn's disease in the era of biologicals:A reduced need or delayed verdict?显示文摘Crohn's disease(CD) is a chronic inflammatory bowel disease that can affect the entire gastrointestinal tract.Ultimately,up to 70% of all patients will need surgery,despite optimized medical therapy.Moreover,about half of the patients will need redo-surgery because of disease recurrence.The introduction of anti-tumor necrosis factor(TNF) drugs(Infliximab in 1998) revolutionized the treatment of CD.Different randomized trials assessed the efficacy of anti-TNF treatment not only to induce,but also to maintain,steroid-free remission.Furthermore,these agents can rapidly lead to mucosal healing.This aspect is important,as it is a major predictor for long-term disease control.Subgroup analyses of responding patients seemed to suggest a reduction in the need for surgery at median-term follow up(1-3 years).However if one looks at population surveys,one does not observe any decline in the need for surgery since the introduction of Infliximab in 1998.The short follow-up term and the exclusion of patients with imminent surgical need in the randomized trials could bias the results.Only 60% of patients respond to induction of anti-TNF therapy,moreover,some patients will actually develop resistance to biologicals.Many patients are diagnosed when stenosing disease has already occurred,obviating the need for biological therapy.In a further attempt to change the actual course of the disease,top down strategies have been progressively implemented.Whether this will indeed obviate surgery for a substantial group of patients remains unclear.For the time being,surgery will still play a pivotal role in the treatment of CD. | Anthony de Buck van Overstraeten Albert Wolthuis André D'Hoore | 2012 | World Journal of Gastroenterology2012，18，29： | 4 |
| 4 | Methodologic quality assessment of red blood cell transfusion guidelines and the evidencebase of more restrictive transfusion thresholds 显示文摘 | Van Remoortel H De Buck E Dieltjens T | 2016 | Transfusion2016，56，2： | 1 |
| 5 | Clostridium perfringens in poultry:an emerging threat for animal and public health显示文摘 | De Buck Pasmans F | 2004 | Avian Pathology2004，33，： | 1 |
| 6 | CD34 + AC133 + cells isolated from cord blood are highly enriched in long- term culture-initiating cells, NOD/SCID-repopulating cells and dendritic cell progenitors 显示文摘 | de Wynter E A Buck D Hart C | 1998 | Stem Cells1998，16，6： | 1 |
| 7 | T-DNA vector backbone sequences are frequently integrated into the genome of transgenic plants obtained by Agrobacterium-mediated transformation 显示文摘 | De Buck S De Wilde C Van Montagu M | 2000 | Mol Breed2000，6，： | 1 |
| 8 | Plants as bioreactors for protein production: avoiding the problem of transgene silencing显示文摘 | De Wilde C Van Houdt H De Buck C | 2000 | Plant Molecular Biology2000，43，： | 1 |
| 9 | Microencapsulated short-chain fatty acids in feed modify colonization and invasion early after infection with Salmonella enteritidis in young chickens 显示文摘 | VAN IMMERSEEL F FIEVEZ V DE BUCK J | 2004 | Poultry Science2004，83，1： | 1 |
| 10 | Farmer Perceptions of Weed Control Techniques in Sugarbeet 显示文摘 | Wossink G A A de Buck A J van Niejenhuis J H | 1997 | Agrieultural Systems1997，，3： | 1 |
| 11 | T- DNA integration patterns in co - transformation plant cells suggest that T- DNA repeats originate from co - integration of separate T - DNAs显示文摘 | de Neve M de Buck S Jaeobs A | 1997 | Plant J1997，11，： | 1 |
| 12 | Clostridium perfringens in poultry: an emerging threat for animal and public health显示文摘 | VAN IMMERSEEL F DE BUCK J PASMANS F | 2004 | Avian Pathol2004，33，6： | 1 |
| 13 | Changes in left atrial anatomy due to respiration:impact on three-dimensional image integration during atrial fibrillation ablation显示文摘 | Ector J De Buck S Loeckx D | 2008 | J Cardiovasc Electrophysiol2008，19，： | 1 |
| 14 | Predicting oral clearance in humans: how close can we get with allometry?显示文摘 | Sinha VK De Buck SS Fenu LA | 2008 | Clin Pharmacokinet2008，47，1： | 1 |
| 15 | Long- term course and outcome of functional capacity in rheumatoid arthritis; the effect of disease activity and radiologic damage o- ver time显示文摘 | Drossaers-Bakker KW de Buck M van Zeben D | 1999 | Arthritis Rheum1999，42，： | 1 |
| 16 | A multidisci-plinary job retention vocational rehabilitation programme for patients with chronic rheumatic diseases:patients' and occupa-tional physicians' satisfaction显示文摘 | de Buck PD Breedveld J van der Giesen FJ | | 0，，05： | 1 |
| 17 | T-DNA integration patterns in co-transformed plant cells suggest that T-DNA repeats originate from co-integration of separate T-DNAs显示文摘 | DE NEVE M DE BUCK S JACOBS A VAN MONTAGU M DEPICKER A | 1997 | The Plant Journal1997，11，1： | 1 |
| 18 | Clostridium perfringens in poultry:an emerging threat for animal and public health 显示文摘 | Van lmmerseel F De Buck J Pasmans F | 2004 | AvianPathol2004，33，： | 1 |
| 19 | Severe combined immunodeficiency and microcephaly in siblings with hypomorphic mutation in DNA ligase IV显示文摘 | Buck D Moshous D de Chasseval R | 2006 | Eur J Immunol2006，36，1： | 1 |
| 20 | A putative twin-arginine translocation pathway in Legionellapneumophila显示文摘 | de Buck E Lebeau I Maes L | 2004 | BiochemBiophys Res Cmun2004，317，： | 1 |
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