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| 1 | 酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。 | 陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB | 2021 | 中华高血压杂志2021，29，2： | 9 |
| 2 | Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors显示文摘AIM:To investigate the expression and potential prognostic role of vascular endothelial growth factor(VEGF) and endoglin in gastroenteropancreatic neuroendocrine tumors(GEP-NETs) . METHODS:Microvessel density(MVD) in GEP-NETs was evaluated using endoglin and CD31 immunohistochemistry.In addition,tissue levels of endoglin and VEGF were determined in homogenates by ELISA. RESULTS:Endoglin was highly expressed on tumor endothelial cells.CD31 MVD in GEP-NETs was significantly higher compared to endoglin MVD(P<0.01) .Two-tofour-fold higher tissue levels of endoglin and VEGF were seen in tumors compared to associated normal tissue. This increased endoglin tissue expression in tumors was significantly related to tumor size(P<0.01) ,presence of metastases(P=0.04) ,and a more advanced tumor stage(P=0.02) ,whereas expression of VEGF was not. CONCLUSION:We suggest that endoglin is a potential marker to indicate and predict metastases,which might be useful in the post-resection therapeutic approach of patients with GEP-NETs. | Patricia Kuiper Lukas JAC Hawinkels Eveline SM de Jonge-Muller Izk Biemond Cornelis BHW Lamers Hein W Verspaget | 2011 | World Journal of Gastroenterology2011，17，2： | 4 |
| 3 | 高危心血管病老年人血压变异性的相关因素显示文摘诊问血压变异性是心血管病的独立预测因素。该研究探讨老年人血压变异的相关因素。方法:在普伐他汀干预高危老年人的前瞻性研究( pravastatin inelderly individuals at risk of vascular disease, PROS-PER)中,分析70~82岁有心血管病史或危险因素的男性和女性者3794人。 | Poortvliet RK Lloyd SM Ford I Sattar N de Craen AJ Wijsman LW Mooijaart SP Westendorp G Jukema JW de Ruijter W Gussekloo J Stott DJ | 2015 | 中华高血压杂志2015，23，10： | 3 |
| 4 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 5 | Identification of severe acute respiratory syndrome in Canada显示文摘 | Poutanen SM Low DE Henry B | 2003 | N Engl J Med2003，348，： | 2 |
| 6 | Surgical treatment of pancreatic adenocarcinoma: actual survival and prognostic factors in 343 patients显示文摘 | Kuhlmann KF DE Castro SM Wesseling JG | 2004 | Eur J Cancer2004，40，4： | 1 |
| 7 | The AD7c-NTP neuronal thread protein biomarker for detecting Alzheimer' s disease 显示文摘 | De La Monte SM Wands JR | 2001 | J Alzheimers Dis2001，3，： | 1 |
| 8 | The right ventricular outflow tracts as an alternative permant pacing site:long-term follow-up显示文摘 | Beain ES Jones SM Wanl DE | 1991 | PACE1991，14，： | 1 |
| 9 | Identification of Severe Acute Respiratory Syndrom in Canda显示文摘 | Poutanen SM Low DE Henry B | 2003 | N Engl J Med2003，10，： | 1 |
| 10 | Increased antibody affinity and specificity by codon-based mutagenesis显示文摘 | Huse WD Yelton DE Glaser SM | 1993 | Int Rev Immunol1993，10，23： | 1 |
| 11 | Repression of the human papillomavirus E6 gene initiates p53-dependent,telomerase independent senescence and apoptosis in hela cervical carcinoma cells显示文摘 | Horner SM De Filippis RA Manuelidis L | 2004 | J Virol2004，78，8： | 1 |
| 12 | Task concentration training and fear of blushing 显示文摘 | Bogels SM Mulkens S de Jong PJ | 1997 | Clinl Psychol Psychother1997，4，4： | 1 |
| 13 | Identification of severe acute respiratory syndrome in Canada显示文摘 | Poutanen SM Low DE Henry B | | 0，，： | 1 |
| 14 | Sushe Community breastfeeding followLup analysis from 2004 to2009显示文摘 | Wang SM Lin DE | 2011 | Medlnf2011，24，6： | 1 |
| 15 | Oxygen free radicalinjury is sufficient to cause some Alzheimer-type molecularabnormalities in human CNS neuronal cells显示文摘 | de la Monte SM Ganju N Feroz N | 2000 | J Alzheimers Dis2000，2，： | 1 |
| 16 | Neuronal thread protein over expression in brains with Alzheimer's disease le sions显示文摘 | de la Monte SM Wands JR | 1992 | Journal of the Neurological Sciences1992，113，2： | 1 |
| 17 | Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial显示文摘 | Smith AD Smith SM de Jager CA | 2010 | PloSone2010，5，9： | 1 |
| 18 | Biochemistry and molecular biology of the human CYP2C subfamily显示文摘 | Goldstein JA de Morais SM | | 0，，： | 1 |
| 19 | Support of hepatic regeneration by trophic factors from liver-derived mesenchymal stromal/stem cells显示文摘 | Fouraschen SM Hall SR de Jonge J | 2014 | Methods Mol Biol2014，1213，： | 1 |
| 20 | Personal Hair Dye Use and Cancer: A Systematic Literature Review and Evaluation of Exposure Assessment in Studies Published Since 1992显示文摘 | Rollison DE Helzlsouer K J Pinney SM | 2006 | J Toxicol Environ Health B Crit Rev2006，9，5： | 1 |
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