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| 1 | Clinical outcome of pediatric collagenous gastritis: Case series and review of literature显示文摘Collagenous gastritis (CG) is characterized by patchy subepithelial collagen bands. Effective treatment and the clinical and histological outcome of CG in children are poorly defined. The aim of this study is to summarize the published literature on the clinical outcome and response to therapy of pediatric CG including two new cases. We performed a search in Pubmed, OVID for related terms; articles including management and clinical and/or endo-histologic follow up information were included and abstracted. Reported findings were pooled in a dedicated database including the corresponding data extracted from chart review in our patients with CG. Twenty-four patients were included (17 females) with a mean age of 11.7 years. The clinical presentation included iron deficiency anemia and dyspepsia. The reported duration of follow up (in 18 patients) ranged between 0.2-14 years. Despite most subjects presenting with anemia including one requiring blood transfusion, oral iron therapy was only documented in 12 patients. Other treatment modalities were antisecretory measures in 13 patients; proton pump inhibitors (12), or histamine-2 blockers (3), sucralfate (5), prednisolone (6), oral budesonide in 3 patients where one received it in fish oil and triple therapy (3). Three (13%) patients showed no clinical improvement despite therapy; conversely 19 out of 22 were reported with improved symptoms including 8 with complete symptom resolution. Spontaneous clinical resolution without antisecretory, anti-inflammatory or gastroprotective agents was noted in 5 patients (4 received only supplemental iron). Follow up endohistopathologic data (17 patients) included persistent collagen band and stable Mononuclear cell infiltrate in 12 patients with histopathologic improvement in 5 patients. Neither collagen band thickness nor mononuclear cell infiltrate correlated with clinical course. Intestinal metaplasia and endocrine cell hyperplasia were reported (1) raising the concern of long term malignant transformation. In summary, CG in children is a chronic disease, typically with a variable clinical response and an indolent course that is distinct from the adult phenotype. Long term therapy usually inclused iron supplementation but cannot be standardized, given the chronicity of the disease, variability of response and potential for adverse events. | Nadia Mazen Hijaz Seth Steven Septer James Degaetano Thomas Mario Attard | 2013 | World Journal of Gastroenterology2013，19，9： | 5 |
| 2 | Cavernous transformation of the portal vein:patterns of intrahepatic and splanchic collateral circulation detected with Doppler sonography显示文摘 | DeGaetano AM Lafortune M Patriquin H | 1995 | AJR1995，165，11： | 1 |
| 3 | Standardization of weekly growing degree day accumulations based on differences in temperature observation time and method显示文摘 | DeGaetano A T Knapp W W | | 0，，： | 1 |
| 4 | Trends in twentieth - century tem- perature extreme across the United States 显示文摘 | DEGAETANO A T ALLEN R J | 2002 | Climate2002，15，： | 1 |
| 5 | Snow drifting transport rates from water flume simulation 显示文摘 | O' Rourke M Degaetano A Tokarezyk J D | 2004 | Journal of Wind Engineering and Industrial Aerodynamics2004，92，1415： | 1 |
| 6 | Analytical simula- tion of snow drift loading显示文摘 | ORourke M Degaetano A Tokarczyk J D | 2005 | Journal of Structural Engineer- ing2005，131，： | 1 |
| 7 | Effects of bilio- pancreatic diversion on diabetes complications: a 10-year follow-up 显示文摘 | IACONELLI A PANUNZI S DEGAETANO A | 2011 | Diabetes Care2011，34，3： | 1 |
| 8 | Snow drifting transport rates from water flume simulation显示文摘 | O'Rourke M Degaetano A Tokarczyk J D | 2004 | Journal of Wind Engineering and Industrial Aerodynamics2004，92，： | 1 |
| 9 | Reversibility of insulin resistance in obese diabetic patients:role of plasma lipids显示文摘 | Mingrone G DeGaetano A Greco AV | 1997 | Diabetologia1997，40，5： | 1 |
| 10 | Snow drifting transport rates from water flume simulation显示文摘 | Michael O’Rourke Arthur DeGaetano Janine Derjue Tokarczyk | 2004 | Journal of Wind Engineering & Industrial Aerodynamics2004，，14： | 1 |
| 11 | Using a discriminant analysis to classify urban and rural climate stations based on diurnal range of temperature and dewpoint depression 显示文摘 | Brown P J Degaetano A T | 2010 | J Climate Appl Meteor2010，49，： | 1 |
| 12 | An east coast winter storm climatology显示文摘 | HIRSCH M E DEGAETANO A T COLUCCI S J | 2001 | J Climate2001，14，： | 1 |
| 13 | Cavernous transformation of the portal vein : Batterns of intrahepatic and splanchic collateral circulation detected with Doppler sonography显示文摘 | DeGaetano AM Lafortune M Patriquin H | 1995 | AJR1995，165，： | 1 |
| 14 | Reversibility of insulin resistance in obese diabetic patients:role of plasma lipids显示文摘 | Mingrone G DeGaetano A Greco AV | 1997 | Diabetolo gia1997，40，： | 1 |
| 15 | Spatial interpolation of daily maximum and minimum air temperature based on meteor- ological model analyses and independent observations 显示文摘 | Degaetano A T Belcher B N | 2007 | Journal of Applied Meteorology and Climatology2007，46，11： | 1 |
| 16 | Giant gastric folds in a pa- tient with hypoalbuminaemia显示文摘 | Gerada J Borg E DeGaetano J | 2013 | BMJ Case Rep2013，2013，： | 1 |
| 17 | Snow drifting transport rates from water flume simulation显示文摘 | Michael O’Rourke Arthur DeGaetano Janine Derjue Tokarczyk | 2004 | Journal of Wind Engineering & Industrial Aerodynamics2004，，14： | 1 |
| 18 | Survey of gunshot residue analysis in forensic science laboratories显示文摘 | DeGaetano D Siegel JA | 1990 | J Forensic Sci1990，35，5： | 1 |
| 19 | Spatial grouping of United States climate stations using a hybrid clustering approach显示文摘 | DeGaetano A T | | 0，，07： | 1 |
| 20 | Attributes of several methods for detecting discontinuities in temperature series: prospects for a hybrid homogenization procedure 显示文摘 | DeGaetano A T | 2006 | Journal of Climate2006，19，： | 1 |
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