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20篇 您的检索式:作者名="Deendayal"
    题名 作者 年代 出处 被引量
1Extracellular biosynthesis of silver nanoparticles using the fungus Fusarium oxysporum显示文摘Absar Ahmad Priyabrata Mukherjee Satyajyoti Senapati Deendayal Mandal M.Islam Khan Rajiv Kumar Murali Sastry 2002Colloids and Surfaces B: Biointerfaces2002,,4:2
2Tissue inhibitors of metalloproteinases : evolution, structure and function 显示文摘Keith Brew Deendayal Dinakarpandian Hideaki Nagase 2000Biochimica et B iophysica Acta2000,1477,:1
3Finding disease similarity based on implicit semantic similarity 显示文摘Sachin Mathur Deendayal Dinakarpandian 2012Journal of Biomedical Informatics2012,45,9:1
4Mutarional analysis of the mature peptide region of inhibin genes in Indian women with ovarian failure显示文摘Dixit H Deendayal Singh L 2004Hum Reprod2004,19,8:1
5Enantioselective bioreduction of acetophenone and its analogous by the fungus Trichothecium sp显示文摘Mandal Deendayal Ahmad Absar Khan M Islam 0,,:1
6Mutational analysis of themature peptide region of inhibin genes in Indian womenwith premature ovarian failure显示文摘Dixit H Deendayal M Singh L 2004Hum Reprod2004,19,8:1
7Biocatalytic transformation of cyclohexanone by Fusarium SP显示文摘Deendayal Mandal Absar Ahamad Mohammed Islam Khan 2002Journal of Molecular Catalysis Chemical2002,181,12:1
8Collagenase unwinds triple-helical collagen prior to peptide bond hydrolysis显示文摘Linda C Deendayal D Naoto Y 2004Embo Journal2004,23,15:1
9The use of microorganisms for the formation of metal nanoparticles and their application显示文摘Deendayal Mandal Mark E. Bolander Debabrata Mukhopadhyay Gobinda Sarkar Priyabrata Mukherjee 2006Applied Microbiology and Biotechnology2006,,5:1
10Finding disease similarity based on implicit semantic similarity显示文摘Sachin Mathur Deendayal Dinakarpandian 2011Journal of Biomedical Informatics2011,,2:1
11Porcine Repro- ductive and Respiratory Syndrome Virus Inhibits Type I Interfer- on Signaling by Blocking STAT1/STAT2 Nuclear Translocation显示文摘Deendayal Patel Yuchen Nan Meiyan Shen 2010Journal of virology2010,84,11:1
12Tissueinhibitors of m etalloproteinases:evolution,structure and Function显示文摘Keith Brew A Deendayal Dinakarpandian B Hideski Nagase B 2000Biochimica et Biophysica Acta2000,267,:1
13Mutational analysis of the mature peptide region of inhibin genes in Indian women with ovarian failure 显示文摘Dixit H Deendayal M Singh L 2004Hum Reprod2004,19,8:1
14An informatics search for the low-molecular weight chromium-binding peptide显示文摘Deendayal Dinakarpandian Vincent Morrissette Shveta Chaudhary 2004BMC Chemical Biology2004,,:1
15Mutation analysis of the mature peptide region of inhibin genes in Indian women with ovarian failure显示文摘Dixit H Deendayal M Singh L 2004Hum Reprod2004,19,8:1
16The use of microorganisms for the formation of metal nanoparticles and their application显示文摘Deendayal Mandal Mark E. Bolander Debabrata Mukhopadhyay Gobinda Sarkar Priyabrata Mukherjee 2006Applied Microbiology and Biotechnology2006,,5:1
17Mutational analysis of t he mature peptide region of inhibin genes in Indian women with ovarian failure 显示文摘Dixit H Deendayal M Singh L 2004Human Reproduction2004,19,8:1
18An Informatics Search for the Low-molecular Weight Chromium-binding Peptide 显示文摘Deendayal D Vincent M Chaudhary S 2004BMC Chem Biol2004,4,:1
19Tissue inhibitors of metalloproteinase: evolution, structure and function 显示文摘Keith B Deendayal D Hideaki N 2005Biochim Biophys Acta2005,1477,:1
20猪繁殖与呼吸综合征病毒通过阻碍STAT1/STAT2核转位抑制Ⅰ型干扰素的信号转导显示文摘Ⅰ型干扰素(IFNs),IFN-α/β诱导抗病毒应答,在天然免疫抗病毒感染中起着重要作用。猪繁殖与呼吸综合征病毒(PRRSV)抑制Ⅰ型干扰素的合成,但其是否抑制IFN的信号转导尚未明确。本研究结果发现PRRSV干扰IFN的信号转导通路。用PRRSV VR2385株感染MARC-145细胞,经IFN-α处理的感染细胞中,干扰素刺激基因ISG15和ISG56的转录、信号转导蛋白及转录激活因子(STAT)2水平均显著低于未经过IFN-α处理过的对照感染细胞。在PRRSV感染的细胞中,IFN诱导的STAT1和STAT2磷酸化及其异源二聚体的形成都未受影响,但大部分的STAT1/STAT2/IRF9的三聚体仍存在于PRRSV感染细胞的细胞质中,表明三聚体的核易位受到了阻碍。PRRSV VR2385感染的细胞中过度表达的NSP1β抑制了ISG15和ISG56的表达,并阻止STAT1的核转位,这些都表明NSP1β可能是抑制IFN信号转导的病毒蛋白。PRRSV感染的猪肺泡巨噬细胞(PAMs)也抑制INF-α刺激的ISG基因和STAT2蛋白的表达。相反,已获批上市的的低致病性疫苗株Ingelvac PRRSV MLA感染PAMs,不需要添加外源的IFN就能活化包括趋化因子和抗病毒细胞因子等IFN诱导基因的表达,且检测不出其对IFN的信号转导产生影响。这些发现都说明PRRSV通过阻碍ISGF3的核转位阻止Ⅰ型干扰素的活化和信号转导通路。Deendayal Patel 程晶 2010中国畜牧兽医2010,37,10:0
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