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| 1 | Heavy cigarette smoking and alcohol consumption are associated with impaired sperm parameters in primary infertile men显示文摘We assessed the concomitant impact of cigarette smoking and alcohol con sumption in men presenting for primary couple's infertility.Data from 189 in fertile men were an a lyzed.Semen analysis,serum hormones,and sperm DNA fragmentation(SDF)were obtained.Smoking status was categorized as follows:current nonsmoker(-S),moderate smoker(+MS),and heavy smoker(+HS).Alcohol consumption was categorized as follows:abstainer(-D),moderate drinker(+MD),and heavy drinker(+HD).Descriptive statistics and logistic regression models were applied.Among all the participants,132(69.8%),30(15.9%),and 27(14.3%)patients were-S,+MS,and+HS,respectively.In addition,67(35.4%),77(40.7%)and 45(23.8%)men were-D,+MD and+HD,respectively.Regarding concomitant habits,52(27.5%)patients were nonsmokers and abstainers(-S/-D:Group 1),91(48.1%)had at least one recreational habit(-S/+D or+S/-D:Group 2),and 46(24.3%)were both smokers and drinkers(+S/+D:Group 3).Sperm concentration and progressive motility were lower in+HS and+HD,compared with-S and-D(all P<0.05),respectively.Similarly,both parameters were significantly lower in Group 3 than Groups 1 and 2(all P<0.05).SDF values were higher in Group 3 than Groups 1 and 2(both P<0.05).In multivariate analysis,follicle-stimulating hormone(FSH)levels and concomitant+S/+D status were independent predictors of impaired sperm concentration and progressive motility(all P<0.05).Heavy smoking and heavy drinking were associated with worse seminal parameters than moderate smoking/drinking and nonsmoking/abstaining.When concomitant,+S/+D status has an even greater detrimental effect on semen parameters. | Luca Boeri Paolo Capogrosso Eugenio Ventimiglia Filippo Pederzoli Walter Cazzaniga Francesco Chierigo Federico Deho Emanuele Montanari Francesco Montorsi Andrea Salonia | 2019 | Asian Journal of Andrology2019，21，5： | 6 |
| 2 | The ageing male and erectile dys- functlon显示文摘 | Montorsi F Salonia A Deho F | 2002 | World J Urol2002，20，1： | 1 |
| 3 | Alprostadil suppresses angiogenesis in vitro and in vivo in the murine Matrigel plug assay显示文摘 | Cattaneo MG Pola S Deho V | 2003 | Br J Pharmacol2003，138，2： | 1 |
| 4 | Pharmacological management of erectile dysfunction显示文摘 | Montorsi F Salonia A Deho F | 2003 | BJU Int2003，91，5： | 1 |
| 5 | Alprostadil suppresses angiogenesis in vitro and in vivo in the murine Matrigel plug assay显示文摘 | Cattaneo MG Pola S Deho V | 2003 | Br J Pharmacol2003，138，2： | 1 |
| 6 | MiR-221 influence effector functions and actin cytoskeleton in mast cells 显示文摘 | Mayoral RJ Deho L Rusca N | 2011 | PLoS One2011，6，26： | 1 |
| 7 | Pharmacological management of erectile dysfunction显示文摘 | Montorsi F Salonia A Deho F | 2003 | BJU Int2003，91，5： | 1 |
| 8 | Alprostadil suppresses angiogenesis in vitro and in vivo in the nurine Matrigel plug assay显示文摘 | Cattaneo MG Pola S Deho V et a1 | 2003 | Br J Pharmacol2003，138，2： | 1 |
| 9 | Overall Clinical Outcomes After Nerve and Seminal Sparing Radical Cystectomy for the Treatment of Organ Confined Bladder Cancer显示文摘 | RENZO COLOMBO ROBERTO BERTINI ANDREA SALONIA RICHARD NASPRO MASSIMO GHEZZI BRUNO MAZZOCCOLI FEDERICO DEHO’ FRANCESCO MONTORSI PATRIZIO RIGATTI | 2004 | The Journal of Urology2004，，5： | 1 |
| 10 | The ageing male and erectile dysfunction显示文摘 | Montorsi F Salonia A Deho F | 2002 | World J Urol2002，20，1： | 1 |
| 11 | Practical photoquantity measurement using a camera显示文摘 | JULIEN DEHOS ERIC ZEGHERS LAURENT SARRY | 2012 | IET Image Processing2012，5，4： | 1 |
| 12 | Emergency management of children with acute severe asthma requiring transfer to intensive care 显示文摘 | Deho A Lutman D Montgomery M | 2010 | Emerg Med J2010，27，11： | 1 |
| 13 | Absolute and Relative Resources as Determinants of International Acquisitions显示文摘 | Anand J Dehos A | 2002 | Strategic Management Journal2002，23，： | 1 |
| 14 | Alprostadil suppresses angiogenesis in vitro and in vivo in the murine matrigel plug assay显示文摘 | Cattaneo MG Pola S Deho V | 2003 | Br J Pharmacol2003，138，2： | 1 |
| 15 | MiR-221 influences effector functions and actin cytoskeleton in mast ceils 显示文摘 | Mayoral RJ Deho L Rusca N | 2011 | PLoS One2011，6，26： | 1 |
| 16 | S1 ribosomal protein and the interplay between translation and mRNA decay 显示文摘 | Delvillani F Papiani G Deho G | 2011 | Nucleic Acids Res2011，39，17： | 1 |
| 17 | MiR-146a and NF- kappaBl regulate mast cell survival and T lymphocyte differentiation 显示文摘 | Rusca N Deho L Montagner S | 2012 | Mol Cell Biol2012，32，21： | 1 |
| 18 | Pharmacological management of erectile dysfunction显示文摘 | Montorsi F Salonia A Deho'F | 2003 | BJU Int2003，91，5： | 1 |
| 19 | MiR-221influences effector functions and actin cytoskeleton in mast cells显示文摘 | Mayoral RJ Deho L Rusca N | 2011 | PLo S One2011，6，26： | 1 |
| 20 | MiR-221 influences effector functions and actin cytoskeleton in mast cells显示文摘 | Mayoral RJ Deho L Rusca N | 2011 | PLoS One2011，6，26： | 1 |
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