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| 1 | Comparison of the Morphology,Structures and Mechanical Properties of Teleost Fish Scales Collected from New Zealand显示文摘The mechanical properties and structures of fish scales have generated considerable research interest,however,comparative studies for different fish scales from difl^rent water regions have not been reported.In this paper,the surface morphologies,hierarchical structures and mechanical properties of four kinds of fish scales collected from freshwater,shallow sea,and deep sea in New Zealand are investigated.The results indicate that the surface morphologies of those fish scales are similar at ventro-lateral,dorso-lateral and anterior locations,and the hierarchical structures of those fish scales all consist of two layers:a bone layer and a collagen layer composed of collagen fibrils.However,the spiral angles of the collagen lamellaes of different scales are different.The largest are Mugil cephalus scales,while the smallest are Cyprinus carpio scales.Comparing the mechanical behaviors of those fish scales,the tensile strength of Carassius auratus scales is the largest,but the ductility is the lowest.Pristipomoides sieboldii scales have the best ductility.Further,the relationship between hierarchical structures and mechanical properties of fish scales is discussed.It is found that the spiral angles of the collagen lamellaes and bond/collagen thickness ratio both have a great influence on the mechanical properties of fish scales. | Deju Zhu Chaohui Zhang Peng Liu Laith A.Jawad | 2019 | Journal of Bionic Engineering2019，16，2： | 6 |
| 2 | Molecular imaging of enzyme activity in vivo using activatable probes显示文摘在有分子的成像探针的生活系统的酶活动的精确测量正在成为一种重要技术解开在生物过程的不同的酶的功能的角色。最近的进步在展示不同成像形式的无数分子的成像探针的开发被取得了,包括光成像,磁性的回声成像,原子成像,和 photoacoustic 成像,允许在有高敏感和高空间分辨率的 vivo 的各种各样的酶活动的非侵略的察觉。在这些成像探针, activatable 或聪明的探针之中,信号能是其成像,明确地交换了从离开到在在和目标酶的相互作用之上的状态上,由于他们的改进敏感和特性是特别地吸引人的。这里,在能够成像的 activatable 探针的发展的最近的进展在 vivo 的不同的酶活动基于不同成像形式被总结,并且当前的挑战和未来观点被讨论。 | Runqi Yan Deju Ye | 2016 | Science Bulletin2016，61，21： | 4 |
| 3 | Structure, Mechanical Behavior and Puncture Resistance of Grass Carp Scales显示文摘这个工作被进行与不同的水内容调查层次结构,机械行为和草鲤鱼规模的破裂抵抗(含水、使 \O 脱水) 并且负担条件(单轴, biaxial 和穿孔机测试) 。规模的整个剖面图被调查,并且多骨的层显示断绝并且部分在骨胶原层嵌入,这被发现。四个不同地点被考虑在下面张力并且穿孔机测试。单轴的张力的测试的结果在规模上显示出在失败模式和表面形态学的分发之间的关联。与单轴的测试的那些相比在张力的力量和年轻模量有次要的差别的 biaxial 测试结果表演,而是最终的紧张是大约 20%-50% 。刺测试也作为底层与针和不同坚硬硅橡胶的不同尺寸被进行。结果证明刺力量和变丑依赖于针的尺寸和底层的坚硬。规模的失败模式与水内容有关。光线的裂缝在含水的规模的多骨的层发生,并且骨胶原纤维在刺地点附近扭动。然而, shear 失败发生在使脱水的规模的多骨的层。 | Peng Liu Deju Zhu Junwen Wang Tinh Quoc Bui | 2017 | Journal of Bionic Engineering2017，14，2： | 3 |
| 4 | Degradable Hybrid CuS Nanoparticles for Imaging-Guided Synergistic Cancer Therapy via Low-Power NIR-II Light Excitation显示文摘Near-infrared(NIR)-II light-excitable photonic agents capable of generating tumor hyperthermia and cytotoxic free radicals are promising for synergistic phototherapy of tumors.However,the lack of NIR-II excitable agents makes it challenging to achieve combinational tumor phototherapy.Here,the authors have reported on a tumor-targeting and degradable hybrid copper sulfide(CuS)nanoparticle(AIBA@CuS-FA)via loading a hydrophilic Azo initiator(AIBA)into an amphiphilic lipid-encapsulating CuS nanoparticle.AIBA@CuS-FA shows high photothermal conversion efficiency(PCE≈47.5%)at 1064 nm,enabling heat production to trigger tumor hyperthermia and thermal decomposition of AIBA into cytotoxic free alkyl radicals upon irradiation with a 1064-nm laser under low-power density(0.5 W/cm2).Moreover,alkyl radicals can drive degradation of AIBA@CuS-FA and embedded CuS nanodisks,releasing Cu^(2+)ions that can catalyze a Fenton-like reaction for hydroxyl radical(•OH)production to promote tumor therapy.Findings demonstrate promise for combinational photothermal therapy(PTT),oxygen-independent alkyl radical therapy,and chemodynamic therapy(CDT)of tumors. | Yidan Sun Hua Shi Xiaoyang Cheng Luyan Wu Yuqi Wang Zhengyang Zhou Jian He Hong-Yuan Chen Deju Ye | 2021 | CCS Chemistry2021，3，5： | 2 |
| 5 | Inelastic neutron scattering and dynamics of ions in the super-ionic conductor Ag2S 显示文摘 | EBBSJO I VASHISHTA P DEJUS R | 1987 | J Phys C Solid State Phys1987，20，： | 1 |
| 6 | Positron Emission Tomography Imaging of Drug‐Induced Tumor Apoptosis with a Caspase‐Triggered Nanoaggregation Probe显示文摘 | Bin Shen Jongho Jeon Mikael Palner Deju Ye Adam Shuhendler Frederick T. Chin Jianghong Rao | 2013 | Angew Chem Int Ed2013，，40： | 1 |
| 7 | Magnetic measurements and tuning of the LCLS prototype undulator显示文摘 | Vasserman I B Sasaki S Dejus R J | 2003 | Nucl Instr Meth2003，507，： | 1 |
| 8 | 显示文摘 | OPITZ R LAMBREVA D M DEJUE W H | 2002 | Macromolecules2002，35，： | 1 |
| 9 | Fabrication of hollow zeolite mierocapsules with tailored shapes and functional- ized interiors 显示文摘 | Dong Angang Wang Yajun Wang Deju | 2003 | Microporous and Mesoporous Materials2003，64，13： | 1 |
| 10 | Coherent optical transition radiation and self-amplified spontaneous emission generated by chicane-compressed electron beams显示文摘 | Lumpkin A H Dejus R J Sereno N S | 2009 | Physical Review Special Toptic Accelerator and Beams2009，12，04： | 1 |
| 11 | XOP:Recent developments显示文摘 | del Rio M R Dejus J | 1998 | SPIE Proceedings1998，3448，： | 1 |
| 12 | Reliability approximation of a Markov queueing system with severe breakdown and repair 显示文摘 | Li Quanlin Xu Deju Cao Jinhua | 1997 | Microelectron Reliab1997，37，8： | 1 |
| 13 | Conversion of fly ash eenosphere to hollow microspheres with zeolite/mullite composite shells显示文摘 | Wang Deju Zhang Yahong Dong Angang | 2003 | AdvFunct Mater2003，13，7： | 1 |
| 14 | Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase显示文摘Human 5-lipoxygenase(5-LOX)is a well-validated drug target and its inhibitors are potential drugs for treating leukotriene-related disorders.Our previous work on structural optimization of the hit compound 2 from our in-house collection identified two lead compounds,3a and 3b,exhibiting a potent inhibitory profile against 5-LOX with IC_(50) values less than 1 mmol/L in cell-based assays.Here,we further optimized these compounds to prepare a class of novel pyrazole derivatives by opening the fusedring system.Several new compounds exhibited more potent inhibitory activity than the lead compounds against 5-LOX.In particular,compound 4e not only suppressed lipopolysaccharide-induced inflammation in brain inflammatory cells and protected neurons from oxidative toxicity,but also significantly decreased infarct damage in a mouse model of cerebral ischemia.Molecular docking analysis further confirmed the consistency of our theoretical results and experimental data.In conclusion,the excellent in vitro andin vivo inhibitory activities of these compounds against 5-LOX suggested that these novel chemical structures have a promising therapeutic potential to treat leukotriene-related disorders. | Yu Zhou Jun Liu Mingyue Zheng Shuli Zheng Chunyi Jiang Xiaomei Zhou Dong Zhang Jihui Zhao Deju Ye Mingfang Zheng Hualiang Jiang Dongxiang Liu Jian Cheng Hong Liu | 2016 | Acta Pharmaceutica Sinica B2016，6，1： | 1 |
| 15 | Evaluation of work safety control systems in construction 显示文摘 | Dejus T | 2005 | Journal of Civil Engineering and Management2005，10，2： | 1 |
| 16 | The water-use efficiency of winter wheat and maize on a salt-affected soil in the Huang-Huai-Hai river plain of China 显示文摘 | Deju Z Jingwen L | 1993 | Agriculture Water Management1993，23，： | 1 |
| 17 | Dynamic tensile testing of fabric-cement composites显示文摘 | ZHV Deju PELED Alva MOBASHER Barzin | 2011 | Construction and Building Materials2011，25，1： | 1 |
| 18 | XOP: A muhiplatform graphical user interface for synchrotron radiation spectral and optics calculations 显示文摘 | SANCHEZ DEL RIO M DEJUS R J | 1997 | SPIE Proc1997，3152，： | 1 |
| 19 | Sensitivity analysis of a simple additive weight method显示文摘 | Zavadskas E K Turskis Z Dejus T | 2007 | International Journal of Management and Decision Making2007，8，56： | 1 |
| 20 | Learning-based Power Efficient Routing Algorithms Balancing Network Lifetime and Packet Delay for Wireless Sensor Networks显示文摘 | WU Wandeng WU Wandeng XU Deju XU Deju ZHU Yihua ZHU Yihua SHEN Zhenwei SHEN Zhenwei TANG Yiping TANG Yiping | 2009 | Chinese Journal of Electronics2009，18，4： | 1 |
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