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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Localization of manganese-superoxide dismutase in peroxisomes isolated from Pisum sativum L显示文摘 | Sandalio L M Palma J M del Río L A | 1987 | Plant Science1987，51，： | 1 |
| 3 | Coloring of titanium through laser oxidation: Comparative study with anodizing 显示文摘 | Perez Del P Ferndndez-Pradas J M Serra P | 2004 | Surface and Coatings Technology2004，187，1： | 1 |
| 4 | Determination of rotenone residues in raw honey by solid-phase extraction and high-performance liquid chromatography 显示文摘 | Jimenez J J Bernal J L Del M J | 2000 | J Chromatogr A2000，871，12： | 1 |
| 5 | Guidelines for the early management of adults with ischemic stroke:a guideline from the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups:The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists显示文摘 | Adams HP Jr Del ZG Alberts M J | 2007 | Circulation2007，115，： | 1 |
| 6 | Progression of HIV infec- tion and mortality by hepatitis C infection in patients with haemophilia over 20 years 显示文摘 | Quintana M Del Amo J Ba'asa A | 2003 | Haemophilia2003，，9： | 1 |
| 7 | MicroRNA-21 in pancreatic cancer:correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity显示文摘 | Giovannetti E Funel N Peters G J Del Chiaro M Erozenci LA Vasile E | | 0，，： | 1 |
| 8 | Giardia duodencdis: adhesion-deficient clones have reduced a- bility to establish infection in Mongolian gerbils 显示文摘 | Hemandez-Sanchez J Linan RF Del Rosario Salinas-Tobon M | 2008 | Exp Para- sitol2008，119，3： | 1 |
| 9 | The role of ecological theory and practice in poverty alleviation and environmental conservation 显示文摘 | DeClerck F Ingram J C Del Rio C M R | 2006 | The Ecological Society of America2006，4，10： | 1 |
| 10 | Mechanical properties of polyester mooring cables 显示文摘 | FERNANDES A C DEL VECCI-IIO C J M CASTRO G A V | 1999 | International Journal of Offshoreand Polar Engineering1999，9，3： | 1 |
| 11 | Guidelines for the early management of adults withischemic stroke: a guideline from the American Heart Association/American Stroke Association StrokeCouncil, ClinicalCardiology Council, CardiovascularRadiology and Inter vent ion Council, and theAtherosclerotic Peripheral VascularDisease andQualityof CareOutcomeinResearchlnterdisciplinary Working Groups:the American Academy of Neurologyaffirms the value of this guideline as an educationaltool for neurologists 显示文摘 | ADAMS H P JR DEL ZOPPO G ALBER TS M J | 2007 | Stroke2007，38，： | 1 |
| 12 | A new energy-integrated pervaporation distillation approach显示文摘 | Del Pozo GOMEZ M T KLEIN A REPKE J | 2008 | Desalination2008，224，： | 1 |
| 13 | Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice显示文摘 | Stewart M J Plautz G E Del Buono L | 1992 | Hum Gene Ther1992，3，3： | 1 |
| 14 | Partial characterization of banana starches oxidized by different levels of sodium hypoehlorite显示文摘 | Sanchez-Rivera M M Garcla-Suarez F J L Velazquez del Valle M | 2005 | Carbohydrate Poly mers2005，62，1： | 1 |
| 15 | Decrease in tear secretion and corneal sensitivity after in situ Keratomileusis显示文摘 | Benitez-del Castillo J M del Rio T Lradrier T | 2001 | Corneal2001，20，1： | 1 |
| 16 | Control of the chemical structure of perhydrous coals : FTIR and Py-GC/MS investigation显示文摘 | IGLESIAS M J del RIIO J C LAGGOUN-D FARGE F CUESTA M J SU REZ-RUIZ I | 2002 | J Anal Appl Pyrolysis2002，62，1： | 1 |
| 17 | Preparation of MoS2 and WS2 catalysts by in situ decomposition of ammonium thiosalts显示文摘 | Alonso G Del Valle M Cruz J Petranovskii V LiceaClaverie A Fuentes S | | 0，，： | 1 |
| 18 | Muhimodal management of lateral epi- condylatgia in rock climbers:a prospective case series显示文摘 | GONZALEZ-IGLESIAS J CLELAND J A DEL ROSARIO GU- TIERREZ-VEGA M | 2011 | J Manip- ulative Physiol Ther2011，34，9： | 1 |
| 19 | Leveraging ecological knowledge to end global poverty 显示文摘 | Del Rio C M R Ingram J C DeClerck F | 2005 | Frontiers in Ecology and the Environment2005，3，9： | 1 |
| 20 | Low educational level: a risk factor for sexually transmitted infections among commercial sex workers in Quito, Ecuador 显示文摘 | Solomon MM Smith M J del Rio C | 2008 | Int J STD AIDS2008，19，4： | 1 |
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