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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Semiclassical dressed states of two-level quantum systems driven by nonresonant and/or strong laser fields 显示文摘 | Santana A Gomez Llorente J M Delgado V | 2001 | Journal of Physical B2001，34，： | 2 |
| 3 | Acute effects of righl ventricular apical pacing on left ventricublr synchrony and mechanics 显示文摘 | Delgado V Tops LF Trines SA el al | 2009 | Circ Arrhythmia Electrophysiol2009，2，： | 1 |
| 4 | Tricuspid annuloplasty prevents right ventrieular dilatation and progression of tricuspid regurgitation in patients with tricuspid annular dilatation undergoing mitral valve repair显示文摘 | van de Veire NR Braun J Delgado V | 2011 | J Thorac Cardiovasc Surg2011，141，6： | 1 |
| 5 | Comparison of aortic root dimensions and geometries before and after transcatheter aortic valve implantation by 2-and 3-dimensional transesophageal echocardiography and multislice computed tomography显示文摘 | Ng AC Delgado V Van der Kley F | | 0，，01： | 1 |
| 6 | Assessment of left ventricular dyssynchrony by speckle tracking strain imag- ing显示文摘 | Delgado V Ypenburg C yon Bommel R J | 2008 | J Am Coil Cardiol2008，51，20： | 1 |
| 7 | Acquired haemophilia: review and meta-analysis focused on therapy and prognostic factors显示文摘 | DELGADO J JIMENEZ-YUSTE V HERNANDEZ-NAVARRO F | 2003 | Br J Haematol2003，121，1： | 1 |
| 8 | Optimal left ven- tricular lead position predicts reverse remodeling and survival after cardiac resynchronization therapy显示文摘 | Ypenburg C van Bommel RJ Delgado V | 2008 | J Am Coil Cardiol2008，52，17： | 1 |
| 9 | Clinical and echocardiographic predictors of nonresponse to cardiac resynchronization therapy 显示文摘 | Shanks M Delgado V Ng AC | 2011 | Am Heart J2011，161，3： | 1 |
| 10 | Plasma fruetosamine to evaluate metabolic control among women with gestational diabetes显示文摘 | Delgado M R Novik A V Cardemil M F | 2011 | Rev Med Chil2011，139，11： | 1 |
| 11 | No increased risk of valvular heart disease in adult poststreptococcal reactive arthritis显示文摘 | van Bemmel JM Delgado V Holman ER | 2009 | Arthritis Rheum2009，60，4： | 1 |
| 12 | Acquired haemophilia:Review and meta-analysis Focused on Therapy and Prognostic Pactors显示文摘 | Jimenez-Yuste V Hernandez-Navarro F | 2003 | Br J Hematol2003，121，1： | 1 |
| 13 | Left atrial strain predicts reverse remodeling after catheter ablation for atrial fibrillation 显示文摘 | Tops LF Delgado V Bertini M | 2011 | J Am Coll Cardio12011，57，3： | 1 |
| 14 | Relative merits of left ventriculardyssynchrony, left ventficular lead position, and myocardial scar to predict long- term survival of ischemic heart failure patients undergoing cardiac resynchroniza- tion therapy 显示文摘 | Delgado V Bommel R J Bertini M | 2011 | Circulation2011，123，1： | 1 |
| 15 | Quantitative assessment of mitral regurgitation:comparison between threedimensional transesophageal echocardiography and magnetic resonance imaging显示文摘 | Shanks M Siebelink HM Delgado V | | 0，，： | 1 |
| 16 | Optimal left ventricular lead position predicts reverse remodeling and survival after cardiac resynchronization therapy显示文摘 | Ypenburg C van Bommel RJ Delgado V | | 0，，17： | 1 |
| 17 | Tricuspid annuloplas- ty prevents right ventricular dilatation and progression of tricuspid regurgitation in patients with tricuspid annular dilatation undergoing mitral valve repair显示文摘 | Van de Veire NR Braun J Delgado V | 2011 | J Thorac Cardiovasc Surg2011，141，6： | 1 |
| 18 | VIP/PACAP oppositely affects immature and mature dendritic cell expression of CD80/CD86 and the stimulatory activity for CD4(+)T cells显示文摘 | Delgado M Reduta A Sharma V | 2004 | J Leukoc Bio2004，75，6： | 1 |
| 19 | Electroacoustic and Dielectric Dispersion of Concentrated Colloidal Suspensions 显示文摘 | Ahualli S Jimenez M L Delgado A V Arroyo F J Carrique F | 2006 | IEEE Transactions on Dielectrics and Electrical Insulation2006，13，： | 1 |
| 20 | Electrokinetic andviscoelastic properties of magnetorheologicalsuspensions of cobalt ferrite 显示文摘 | Juan D V Juan D G D Delgado A V | 2001 | Colloids and Surfaces A:Physicochemical and Engineering Aspects2001，195，1： | 1 |
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