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13篇 您的检索式：作者名="Delsite"

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		题名	作者	年代	出处	被引量
	1	DNA repair and synthetic lethality显示文摘Tumors often have DNA repair defects, suggesting additional inhibition of other DNA repair pathways in tumors may lead to synthetic lethality. Accumulating data demonstrate that DNA repair-defective tumors, in particular homologous recombination (HR), are highly sensitive to DNA-damaging agents. Thus, HR-defective tumors exhibit potential vulnerability to the synthetic lethality approach, which may lead to new therapeutic strategies. It is well known that poly (adenosine diphosphate (ADP)-ribose) polymerase (PARP) inhibitors show the synthetically lethal effect in tumors defective in BRCA1 or BRCA2 genes encoded proteins that are required for efficient HR. In this review, we summarize the strategies of targeting DNA repair pathways and other DNA metabolic functions to cause synthetic lethality in HR-defective tumor cells.	Gong-she Guo Feng-mei Zhang Rui-jie Gao Robert Delsite Zhi-hui Feng Simon N. Powell	2011	International Journal of Oral Science2011，3，4：	2
	2	Chemotaxis and chemokinesis of human Prostate turnorcell lines in response to human prostate slromal cell secretory proteins Containing a nerve :7oth,th factor-like protein显示文摘	Djakiew D Pllug BR Delsite R	1993	Cancer Res1993，53，6：	1
	3	Nuclear geninvolved in mitochondrial-to-nucleus communication in breacancer cells 显示文摘	Delsite R Kachhap S Anbazhagnn R	2002	Mol Cancer2002，1，1：	1
	4	Chemotaxis and chemokinesis of human prostate tumor cell lines in response to human prostate stromal cell secretory proteins containing a nerve growth factor-like protein显示文摘	Djakiew D Pflug BR Delsite R	1993	Cancer Res1993，53，6：	1
	5	Anti-proliferative effect of the kinase inhibitor K252a on human prostatic carcinoma cell lines显示文摘	Delsite R Djakiew D	1996	J Androl1996，17，5：	1
	6	Mitochandrial impairment is accompanied by impaired oxidative DNA repair in the nucleus 显示文摘	Delsite RL Rasmussen LJ Rasmussen AK et 02	2003	Mutagenesis2003，18，6：	1
	7	Loss of p53 function in colon cancer cells results phosphochine and total choline显示文摘	Mori N Delsite R Natarajan K	2004	Molecular Imaging2004，3，4：	1
	8	Nuclear genes involved in mitochondrial-to-nucleus communication in breast cancer cells 显示文摘	Kachhap S Anbazhagnn R	2002	Mol Cancer2002，1，1：	1
	9	Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells显示文摘	Delsite R Kachhap S Anbazhagan R	2002	Mol Cancer2002，1，：	1
	10	Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells显示文摘	Delsite R Kachhap S Anbazhagan R	2002	Mol Cancer2002，1，1：	1
	11	Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells 显示文摘	Delsite R Kachhap S Anbazhagan R	2002	Mol Cancer2002，1，：	1
	12	Loss of p53 function in colon cancer cells results phosphochine and total choline显示文摘	Mori N Delsite R Natarajan K		0，，04：	1
	13	应对抑郁显示文摘如果你感到情绪低落、茫然和孤独,别担心,你可以得到帮助。	Alison Delsite Everett 张国庆(译)	2013	英语广场2013，，11：	0

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