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51篇 您的检索式：作者名="Denecke M"

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	题名	作者	年代	出处	被引量
1	Streptozocin/5-fluorouracil chemotherapy is associated with durable response in patients with advanced pancreatic neureendocrine turnouts 显示文摘	Dilz L M Denecke T Steffen I G	2015	Eur J Cancer2015，51，10：	1
2	Smad7 dependent expression signature highlights BMP2 and HK2 signaling in HSC transdifferentiation显示文摘AIM: To analyse the influence of Smad7, antagonist of transforming growth factor (TGF)-β canonical signaling pathways on hepatic stellate cell (HSC) transdifferentia-tion in detail. METHODS: We systematically analysed genes regulated by TGF-β/Smad7 in activated HSCs by microarray analy-sis and validated the results using real time polymerase chain reaction and Western blotting analysis. RESULTS: We identif ied 100 known and unknown tar-gets underlying the regulation of Smad7 expression and delineated 8 gene ontology groups. Hk2, involved in glycolysis, was one of the most downregulated proteins, while BMP2, activator of the Smad1/5/8 pathway, was extremely upregulated by Smad7. However, BMP2 de-pendent Smad1 activation could be inhibited in vitro by Smad7 overexpression in HSCs. CONCLUSION: We conclude (1) the existence of a tight crosstalk of TGF-β and BMP2 pathways in HSCs and (2) a Smad7 dependently decreased sugar metabolism ameliorates HSC activation probably by energy with-drawal.	Bernd Denecke Lucia Wickert Loredana Ciuclan Steven Dooley Nadja M Meindl-Beinker Yan Liu	2010	World Journal of Gastroenterology2010，16，41：	1
3	Asym- metrical dimethylarginine - - more sensitive than NT - pmBNP to diagnose heart failure in adults with congenital heart disease 显示文摘	TUTAREL O DENECKE A BODE BOGER S M	2012	PLoS One2012，7，33：	1
4	Solid state ^13C and in situ1 H NMR study on the effect of melamine on the thermal degradation of a flexible polyurethane foam显示文摘	DICK C M DENECKER C Liggat J J	2000	Polymer International2000，49，10：	1
5	查看详情显示文摘	Denecke M A Pompe S Reich T		0，，：	1
6	Solid state ^13C and in situ ^1H NMR study on the effect of melamine on the thermal degradation of a flexible polyurethane foam显示文摘	Dick C M Denecker C Liggat J J	2000	Polymer International2000，49，10：	1
7	Regulation of the expression and processing of caspase-12 显示文摘	Kalai M Lamkanfi M Denecker G	2003	J Cell Biol2003，162，3：	1
8	Phenylketonuria:no specific frontal lobe-dependent neuropsychological deficits of early treated patients in comparison to diabetic patients显示文摘	Feldman R Denecke J Pietsch M	2002	Pediatr Res2002，51，：	1
9	Frontal lobe-dependent functions in treated phenylketonuria:Blood phenylalanine concentrations and long-term deficits in adolescents and young adults显示文摘	Feldmann R Denecke J Grenzebach M	2005	J Inherit Metab Dis2005，28，：	1
10	Cloning,sequence analysis and expression of a cDNA encoding active phosphoenolpyruvate carboxylase of the C3 plant Solanum tuberosum显示文摘	Merkelbach S Gehlen J Denecke M	1993	Plant Molecular Biology1993，23，4：	1
11	Neurofibromatosis type 1: motor and cognitive function and T2- weighted MRI hyperintensities显示文摘	Feldmann R Denecke J Grenzebach M	2003	Neurology2003，61，12：	1
12	Confocal Micrometer-Scale X-Ray Fluorescence and X-Ray Absorption Fine Structure Studies of Uranium Speciation in a Tertiary Sediment From a Waste Disposal Natural Analogue Site显示文摘	Denecke M A Janssens K Proost K		0，，：	1
13	Electron spectroscopic studies of vapor-deposited Co layer on MoO3 surfaces显示文摘	Probst M Vop M Denecke R	2001	J Electron Spectrosc Relat Phenom2001，114，116：	1
14	Regulation of the expression and processing of caspase-12 显示文摘	KALAI M LAMKANFI M DENECKER G	2003	Cell Biol2003，162，3：	1
15	Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation显示文摘	DAEMEN M A VEER C DENECKER G	1999	J Clin Invest1999，104，5：	1
16	The bar gene as selective and screen able marker in plant engineering显示文摘	DHalluin K De Block M Denecke J	1992	Methods in Enzymology1992，216，：	1
17	Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability显示文摘	Quimbaya M Raspé E Denecker G	2014	Neoplasia2014，16，9：	1
18	Results of ajmaline testing in patients with arrhythmogenic right ventrlcular dysplasia-cardiomyopathy显示文摘	Peters S Trummel M Denecke S	2004	Int J Cardiol2004，95，23：	1
19	Necrosis is associated with IL-6 production but apoptosis is not 显示文摘	Vanden Berghe T Kalai M Denecker G	2006	Cell Signal2006，18，3：	1
20	ldl is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells显示文摘	Wiercinska E Wickert L Denecke B Said H M Hamzavi J Gressner A M	2006	Hepatology2006，43，：	1

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