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| 1 | A novel colloidal gold immunochromatography assay strip for the diagnosis of schistosomiasis japonica in domestic animals显示文摘Background:Schistosomiasis remains a major public health concern in China and an epidemiological survey has revealed that schistosome-infected bovines and goats are the main transmission sources for the disease.Therefore,development of a sensitive technique for the diagnosis of schistosomiasis in domestic animals is necessary.Method:A novel colloidal gold immunochromatography assay(GICA)strip was developed for detecting Schistosoma japonicum in domestic animals.The colloidal gold was conjugated with recombinant streptococcal protein G(rSPG).As the test and control lines,the schistosome soluble egg antigen and rSPG,respectively,were blotted on nitrocellulose membrane.Results:The lowest detectable serum dilution was 1∶640 for schistosome-infected buffaloes.The cross-reaction rate of GICA was 14.29%with Paramphistomum sp.in buffaloes,16.67%with Haemonchus sp.in goats,and 33.33%with Orientobilharzia sp.in goats.These results were slightly lower and similar to those obtained through ELISA.Moreover,the strips for detecting S.japonicum in mice,rabbits,buffaloes,and goats showed high sensitivity(100.00%,100.00%,100.00%,and 100.00%,respectively)and specificity(100.00%,100.00%,94.23%,and 88.64%,respectively).And the sensitivity or specificity of the GICA strips did not present any significant differences after storage for 12 months at room temperature.When compared with ELISA,the GICA strips exhibited similar sensitivity and specificity in the diagnosis of schistosomiasis in mice,rabbits,buffaloes,and goats.Besides,only 5μl of serum are required for the test and the detection can be completed within 5 min.Conclusion:This study is the first to develop a GICA strip using gold-rSPG conjugate for the diagnosing of schistosomiasis in domestic animals,and preliminary results showed that the developed strip may be suitable for large-scale screening of schistosomiasis in endemic areas. | Rui Xu Jintao Feng Yang Hong Chao Lv Dengyun Zhao Jiaojiao Lin Ke Lu Hao Li Jinming Liu Xiaodan Cao Tao Wang Jinli Zai Zhaozhe Wang Bingguang Jia Qian Han Chuangang Zhu | 2017 | Infectious Diseases of Poverty2017，6，1： | 12 |
| 2 | Enhanced aromatic selectivity by the sheet-like ZSM-5 in syngas conversion显示文摘Aromatics are important basic chemicals. However, direct conversion of syngas via the conventional Fischer-Tropsch synthesis produces little aromatics. We presented herein that a bifunctional composite of ZSM-5 in combination with Zn Cr Oxcatalyzes syngas conversion to aromatics. Particularly, ZSM-5 crystals with a sheet-like morphology can enhance significantly the aromatization activity. The lower length ratio of the b/a axes of the crystals, the more aromatics form but without influencing the selectivity of small molecules such as CH4 and C2–C4. Since the acid properties and the Al chemical environment were not altered while the morphology changed, the enhanced aromatic selectivity is likely attributed to the favored diffusion of aromatics in these sheet-like crystals. | Junhao Yang Ke Gong Dengyun Miao Feng Jiao Xiulian Pan Xiangju Meng Fengshou Xiao Xinhe Bao | 2019 | Journal of Energy Chemistry2019，28，8： | 10 |
| 3 | Selective conversion of syngas to propane over ZnCrO_x-SSZ-39 OX-ZEO catalysts显示文摘Oxide-Zeolite(OX-ZEO) bifunctional catalyst design concept has been exemplified in several processes to direct conversion syngas to value-added chemicals and fuels such as mixed light olefins, ethylene, aromatics and gasoline.Herein we demonstrate that the product can be steered toward liquefied petroleum gas(LPG) with a selectivity up to 89% in hydrocarbons especially propane selectivity reaching 80% at CO conversion of 63% using ZnCrOx-H-SSZ-39 catalyst.Interestingly, the quantity of the acid sites of SSZ-39 does not influence obviously the hydrocarbon distribution but the strength is crucial for selective formation of propane.This finding provides an alternative route of LPG synthesis from a variety of carbon resources via syngas. | Gen Li Feng Jiao Dengyun Miao Yong Wang Xiulian Pan Toshiyuki Yokoi Xiangju Meng Feng-Shou Xiao Andrei-Nicolae Parvulescu Ulrich Müller Xinhe Bao | 2019 | Journal of Energy Chemistry2019，28，9： | 6 |
| 4 | CH_4 and N_2O emissions from double-rice cropping system as affected by Chinese milk vetch and straw incorporation in southern China显示文摘Chinese milk vetch(CMV) and rice straw(RS)were incorporated into soil to substitute for synthetic N fertilizers and to maintain soil fertility. However, little is known about the integrated impacts of CMV and RS incorporation on CH_4 and N_2O emissions in double-rice cropping systems in southern China. A field experiment was conducted to estimate the integrated impacts of CMV and RS incorporation in the early-and late-rice seasons on CH_4 and N_2O emissions. All treatments received uniform N inputs, 6%–37% of which was replaced by CMV and RS crop residue. CMV and/or RS incorporation produced equivalent or slightly more grain yield, while reducing N2 O emissions by 3%–43%. However, both CMV and RS incorporation increased CH_4 emissions. Annual CH_4 emissions ranged from 321 to 614 kg·hm^(–2)from CMV and RS amendment treatments, which were 1.5–2.9 times higher than that from synthetic N. Compared with single synthetic N fertilizer, incorporation of CMV and/or RS increased GWP and yield-scaled GWP by 45%–164% and45%–153%, respectively. Our results demonstrate CMV and RS amendments replacing N fertilizer, maintained stable yield, mitigated N_2O emission, but enhanced CH_4 emission. Further study is needed on crop residue management in double-cropping rice systems. | Heshui XU Dengyun LI Bo ZHU Kai ZHANG Yadong YANG Chen WANG Ying JIANG Zhaohai ZENG | 2017 | Frontiers of Agricultural Science and Engineering2017，4，1： | 5 |
| 5 | Technological breakthroughs and scientific progress of the Chang’e-4 mission显示文摘Chang’e-4 is the first man-made probe that accomplished landing and roving on the far side of the Moon,which is viewed as a new milestone in the history of Lunar exploration.Beginning with a brief introduction to the progress of domestic and foreign Lunar exploration,this paper reviews the implementation process of the Chang’e-4 project,sorts out the technical breakthroughs achieved,summarizes the exploration achievements,and provides references for subsequent Lunar exploration. | Weiren WU Dengyun YU Chi WANG Jizhong LIU Yuhua TANG He ZHANG Zhe ZHANG | 2020 | Science China(Information Sciences)2020，63，10： | 3 |
| 6 | A versatile method for the encapsulation of various non-precious metal nanoparticles inside single-walled carbon nanotubes显示文摘 | Tingting Cui Xiulian Pan Jinhu Dong Shu Miao Dengyun Miao Xinhe Bao | 2018 | Nano Research2018，11，6： | 2 |
| 7 | Transient characteristics verification method for DC transformer used in flexible HVDC system显示文摘Previous studies have proposed higher requirements for the transient characteristics of a DC transformer used in a flexible high-voltage direct current(HVDC) system to achieve faster sampling speed and meet wider bandwidth requirements of the control and protection signal, and to eventually suppress the large transient fault current. In this study, a transient characteristics verification method is proposed for transient characteristics verification of a DC transformer used in a flexible HVDC system based on resampling technology and LabVIEW measurement technology after analyzing the key technology for transient characteristics verification of a DC transformer. A laboratory experiment for the transient characteristics of a full-fiber electronic DC transformer is conducted, and experimental results show that such verification method can be employed for frequency response and step response verification of a DC transformer at 10% of the rated voltage and current, and can eventually improve the screening of a DC transformer. | Qi Nie Haoliang Hu Dengyun Li Boyang Liu He Li Qianzhu Xiong | 2019 | Global Energy Interconnection2019，2，2： | 2 |
| 8 | The Interpretation of Seismogenic Fault of the Maduo Mw 7.3Earthquake,Qinghai Based on Remote Sensing Images——A Branch of the East Kunlun Fault System显示文摘On May 22,2021,a Mw 7.3 earthquake occurred in Maduo County,Qinghai Province with the epicenter of 34.59°N,98.34°E.The distribution of aftershocks and surface ruptures suggested that the seismogenic structure might be the Jiangcuo fault(JF),~70 km south of East Kunlun fault(EKLF).Due to the high altitude and sparse human habitats,there are very few researches on the Jiangcuo fault,which makes us know little about the deformation features and even the geometry of Jiangcuo fault.In this study,we used the high-resolution pre-earthquake satellite images to interpret the spatial distribution and geometry of the Jiangcuo fault.Our results show that the Jiangcuo fault strikes nearly east,extending 180-km-long from Eling Lake to east of Changmahe Town.Based on the geometric features,the Jiangcuo fault could be divided into three segments characterized as the linear structures,fault valleys,scarps and systematic offset of channels.The boundary between Bayan Har Block and Qaidam Block is presented as a wide deformation zone named of Kunlun belt that is composed of East Kunlun fault and several branch faults around Anemaqen Mountain.Geometric analysis and deep lithosphere structure around Maduo County suggest that the Jiangcuo fault should be one of branch of East Kunlun fault at south,where the Kunlun fault developed as a giant flower structure.In addition,the seismic hazards potential of Jiangcuo fault should be given enough attention in the future,because west of the Jiangcuo fault,there is a rupture gap between the co-seismic surface ruptures of the 2001 Kunlun,2021 Maduo and 1937 Huashixia Earthquakes. | Guanghao Ha Jinrui Liu Zhikun Ren Xiaoxiao Zhu Guodong Bao Dengyun Wu Zhiliang Zhang | 2022 | Journal of Earth Science2022，33，4： | 1 |
| 9 | Erianin suppresses constitutive activation of MAPK signaling pathway by inhibition of CRAF and MEK1/2显示文摘Constitutive activation of RAS-RAF-MEK-ERK signaling pathway(MAPK pathway)frequently occurs in many cancers harboring RAS or RAF oncogenic mutations.Because of the paradoxical activation induced by a single use of BRAF or MEK inhibitors,dual-target RAF and MEK treatment is thought to be a promising strategy.In this work,we evaluated erianin is a novel inhibitor of CRAF and MEK1/2 kinases,thus suppressing constitutive activation of the MAPK signaling pathway induced by BRAF V600E or RAS mutations.KinaseProfiler enzyme profiling,surface plasmon resonance(SPR),isothermal titration calorimetry(ITC),cellular thermal shift assay,computational docking,and molecular dynamics simulations were utilized to screen and identify erianin binding to CRAF and MEK1/2.Kinase assay,luminescent ADP detection assay,and enzyme kinetics assay were investigated to identify the efficiency of erianin in CRAF and MEK1/2 kinase activity.Notably,erianin suppressed BRAF V600E or RAS mutant melanoma and colorectal cancer cell by inhibiting MEK1/2 and CRAF but not BRAF kinase activity.Moreover,erianin attenuated melanoma and colorectal cancer in vivo.Overall,we provide a promising leading compound for BRAF V600E or RAS mutant melanoma and colorectal cancer through dual targeting of CRAF and MEK1/2. | Penglei Wang Xuechao Jia Bingbing Lu Han Huang Jialin Liu Xuejiao Liu Qiong Wu Yamei Hu Pan Li Huifang Wei Tingting Liu Dengyun Zhao Lingwei Zhang Xueli Tian Yanan Jiang Yan Qiao Wenna Nie Xinli Ma Ruihua Bai Cong Peng Zigang Dong Kangdong Liu | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 1 |
| 10 | Porous graphitic carbons prepared by combining chemical activation with catalytic graphitization显示文摘 | Dengyun Zhai Hongda Du Baohua Li Yuan Zhu Feiyu Kang | 2010 | Carbon2010，，2： | 1 |
| 11 | 显示文摘 | DENGYun wUYing LIYufei(邓云 吴颖 李云飞) | 2006 | 农业机械学报2006，37，8： | 1 |
| 12 | Application of Ultrasonic Motor to Control of Moment Gyroscope Gimbal Servo System显示文摘Attitude control system is one of the most important subsystems in a spacecraft.As a key actuator,the control moment gyroscope(CMG)mainly determines the performance of attitude control system.Whereas,the control accuracy and output torque smoothness of the CMG depends more on its gimbal servo system.Considering the constraints of size,mass and power consumption for a small satellite,here,a mini-CMG is designed,in which the gimbal servo system is driven by an ultrasonic motor.The good performances of the CMG are obtained by both the ultrasonic motor and the rotary inductosyn.The direct drive of gimbal improves its dynamic performance,with the output bandwidth above 20 Hz.The angular and speed closed-loop control obtains the 0.02°/s gimbal rate,and the output torque resolution better than 2×10^(-3) N·m.The ultrasonic motor provides 1.0N·m self-lock torque during power-off,with 12arc-second position accuracy. | Wu Jintao Pan Song Zhao Lei Wu Dengyun Zhang Jiyang | 2017 | Transactions of Nanjing University of Aeronautics and Astronautics2017，34，1： | 1 |
| 13 | Modeling and on-line measurement of drying stress of Pinus rnassoniana hoard 显示文摘 | Tu Dengyun Gu Lianhai | 2007 | Drying Technology2007，25，13： | 1 |
| 14 | Preparation of mesophase pitch based activated carbons for electric double Layer capacitors with high energy density 显示文摘 | Dengyun Zhai Baohua Li Feiyu Kang | 2010 | Mi- croporous and Mesoporous Materials2010，130，： | 1 |
| 15 | Biophotonic probes for bio-detection and imaging显示文摘The rapid development of biophotonics and biomedical sciences makes a high demand on photonic structures to be interfaced with biological systems that are capable of manipulating light at small scales for sensitive detection of biological signals and precise imaging of cellular structures.However,conventional photonic structures based on artificial materials(either inorganic or toxic organic)inevitably show incompatibility and invasiveness when interfacing with biological systems.The design of biophotonic probes from the abundant natural materials,particularly biological entities such as virus,cells and tissues,with the capability of multifunctional light manipulation at target sites greatly increases the biocompatibility and minimizes the invasiveness to biological microenvironment.In this review,advances in biophotonic probes for bio-detection and imaging are reviewed.We emphatically and systematically describe biological entities-based photonic probes that offer appropriate optical properties,biocompatibility,and biodegradability with different optical functions from light generation,to light transportation and light modulation.Three representative biophotonic probes,i.e.,biological lasers,cell-based biophotonic waveguides and biomicrolenses,are reviewed with applications for bio-detection and imaging.Finally,perspectives on future opportunities and potential improvements of biophotonic probes are also provided. | Ting Pan Dengyun Lu Hongbao Xin Baojun Li | 2021 | Light(Science & Applications)2021，10，7： | 0 |
| 16 | Scientific objectives and payload configuration of the Chang’E-7 mission显示文摘As the cornerstone mission of the fourth phase of the Chinese Lunar Exploration Program,Chang’E-7(CE-7)was officially approved,and implementation started in 2022,including a main probe and a communication relay satellite.The main probe,consisting of an orbiter,a lander,a rover and a mini-flying probe,is scheduled to be launched in 2026.The lander will land on Shackleton crater’s illuminated rim near the lunar south pole,along with the rover and mini-flying probe.The relay satellite(named Queqiao-2)will be launched in February 2024 as an independent mission to support relay communication during scientific exploration undertaken by Chang’E-4,the upcoming Chang’E-6 in 2024 and subsequent lunar missions.The CE-7 mission is mainly aimed at scientific and resource exploration of the lunar south pole.We present CE-7’s scientific objectives,the scientific payloads configuration and the main functions for each scientific payload with its key technical specifications. | Chi Wang Yingzhuo Jia Changbin Xue Yangting Lin Jianzhong Liu Xiaohui Fu Lin Xu Yun Huang Yufen Zhao Yigang Xu Rui Gao Yong Wei Yuhua Tang Dengyun Yu Yongliao Zou | 2024 | National Science Review2024，11，2： | 0 |
| 17 | Rigidity Theorems of Complete Ricci Solitons under L^p显示文摘We prove rigidity results of complete Ricci soliton under some Lpconditions and some curvature assumptions. | Haiping FU Dengyun YANG | 2014 | Journal of Mathematical Research with Applications2014，34，6： | 0 |
| 18 | minimal genome design to maximally guarantee fertile inter-subspecific hybrid rice显示文摘Hybrid rice has made considerable contributions to achieve the ambitious goal of food security for the world's population.Hybrid rice from indica/xian and japonica/geng subspecies shows much higher heter-osis and is thereby an important innovation in promoting rice production in the next decade.However,such inter-subspecific hybrid rice has long suffered from serious hybrid sterility,which is a major challenge that needs to be addressed.In this study,we performed a genome design strategy to produce fertile inter-subspecific hybrid by creation of wide compatibility varieties that are able to overcome hybrid sterility.Based on combined genetic analyses in two indica-japonica crosses,we determined that four hybrid ste-rility loci,S5,f5,pf12 and Sc,are the major QTLs controlling inter-subspecific hybrid sterility and thus the minimal targets that can be manipulated for breeding sub-specific hybrid rice.We then cloned the pf12 lo-cus,one of the most effective loci for hybrid male sterility,by map-based cloning,and showed that artificial disruption of pf12A gene at this locus could successfully rescue hybrid fertility.We further dissected the genetic basis of wide compatibility using three pairwise crosses from a wide-compatibility variety Dular and representative indica and japonica varieties.On this basis,we constructed and assembled different combinations of naturally compatible alleles of four loci,S5,Sc,pf12,and f5,and found that the improved lines could fully recover pollen and embryo sac fertility in test-crossed F,s,thereby completely fulfilling the demands of inter-subspecific hybrid spikelet fertility in agricultural production.This breeding scheme would facilitate redesign of future inter-subspecific hybrid rice with a higher yield potential. | Penghui Zhou Zhengji Wang Xingchen Zhu Yao Tang Liang Ye Huihui Yu Yating Li Ningke Zhang Ting Liu Tian Wang Yuying Wu Dengyun Cao Yuan Chen Xu Li Qinglu Zhang Jinghua Xiao Sibin Yu Qifa Zhang Jiaming Mi Yidan Ouyang | 2023 | Molecular Plant2023，16，4： | 0 |
| 19 | CASC Achievements in 2014显示文摘2014 was a remarkable year for CASC.Though there was no manned space flights nor Bei Dou navigation satellite launches during the year,national major space programs proceeded well with remarkable achievements.Quite important progress was made in the aspects of CASC space sectors such as application satellites。 | YU Dengyun | 2015 | Aerospace China2015，16，1： | 0 |
| 20 | Light-controlled soft bio-microrobot显示文摘Micro/nanorobots hold exciting prospects for biomedical and even clinical applications due to their small size and high controllability.However,it is still a big challenge to maneuver micro/nanorobots into narrow spaces with high deformability and adaptability to perform complicated biomedical tasks.Here,we report a light-controlled soft bio-microrobots(called“Ebot”)based on Euglena gracilis that are capable of performing multiple tasks in narrow microenvironments including intestinal mucosa with high controllability,deformability and adaptability.The motion of the Ebot can be precisely navigated via light-controlled polygonal flagellum beating.Moreover,the Ebot shows highly controlled deformability with different light illumination duration,which allows it to pass through narrow and curved microchannels with high adaptability.With these features,Ebots are able to execute multiple tasks,such as targeted drug delivery,selective removal of diseased cells in intestinal mucosa,as well as photodynamic therapy.This light-controlled Ebot provides a new bio-microrobotic tool,with many new possibilities for biomedical task execution in narrow and complicated spaces where conventional tools are difficult to access due to the lack of deformability and bio-adaptability. | Jianyun Xiong Xing Li Ziyi He Yang Shi Ting Pan Guoshuai Zhu Dengyun Lu Hongbao Xin | 2024 | Light(Science & Applications)2024，13，3： | 0 |
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