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| 1 | Helicobacter pylori in human health and disease:Mechanisms for local gastric and systemic effects显示文摘Helicobacter pylori(H. pylori) is present in roughly 50% of the human population worldwide and infection levels reach over 70% in developing countries. The infection has classically been associated with different gastro-intestinal diseases, but also with extra gastric diseases. Despite such associations, the bacterium frequently persists in the human host without inducing disease, and it has been suggested that H. pylori may also play a beneficial role in health. To understand how H. pylori can produce such diverse effects in the human host, several studies have focused on understanding the local and systemic effects triggered by this bacterium. One of the main mechanisms by which H. pylori is thought to damage the host is by inducing local and systemic inflammation. However, more recently, studies are beginning to focus on the effects of H. pylori and its metabolism on the gastric and intestinal microbiome. The objective of this review is to discuss how H. pylori has co-evolved with humans, how H. pylori presence is associated with positive and negative effects in human health and how inflammation and/or changes in the microbiome are associated with the observed outcomes. | Denisse Bravo Anilei Hoare Cristopher Soto Manuel A Valenzuela Andrew FG Quest | 2018 | World Journal of Gastroenterology2018，24，28： | 32 |
| 2 | Leuprolide acetate induces structural and functional recovery of injured spinal cord in rats显示文摘Gonadotropin-releasing hormone(Gn RH) and its synthetic analog leuprolide acetate, a Gn RH agonist, have neurotrophic properties. This study was designed to determine whether administration of leuprolide acetate can improve locomotor behavior, gait, micturition reflex, spinal cord morphology and the amount of microglia in the lesion epicenter after spinal cord injury in rats. Rats with spinal cord compression injury were administered leuprolide acetate or saline solution for 5 weeks. At the 5th week, leuprolide acetate-treated rats showed locomotor activity recovery by 38%, had improvement in kinematic gait and exhibited voiding reflex recovery by 60%, as compared with the 1st week. By contrast, saline solution-treated rats showed locomotor activity recovery only by 7%, but voiding reflex did not recover. More importantly, leuprolide acetate treatment reduced microglial immunological reaction and induced a trend towards greater area of white and gray matter in the spinal cord. Therefore, leuprolide acetate has great potential to repair spinal cord injury. | Carmen Díaz Galindo Beatriz Gómez-González Eva Salinas Denisse Calderón-Vallejo Irma Hernández-Jasso Eduardo Bautista J Luis Quintanar | 2015 | Neural Regeneration Research2015，10，11： | 2 |
| 3 | Trypanosoma rangeli:growth in mammalian cells in vitro and action of a repositioned drug(17-AAG)and a natural extract(Artemisia sp.essential oil)显示文摘Trypanosoma rangeli and T.cruzi are both parasitic unicellular species that infect humans.Unlike T.cruzi,the causative agent of Chagas disease,T.rangeli is an infective and non-pathogenic parasite for humans,but pathogenic for vectors from the Rhodnius genus.Because both species can coexist in different hosts and overlap their infective cycles but very little is known about the infection of T.rangeli in mammalian cells,we decided to characterize both the development of this parasite in cell culture and the effect of therapeutic agents with potential trypanocidal action on it.We found that T.rangeli exhibits a cycle of infection in Vero cells similar to that for T.cruzi and that the repurposed drug,17-AAG,and the natural extract Artemisia sp.essential oil produce a toxic effect on epimastigotes showing a trypanocidal action from the fifth day of culture.Both treatments also affected the infection of trypomastigotes and reduced the capacity of replication of amastigotes of T.rangeli.Since T.cruzi/T.rangeli coinfection cases have been reported,the finding of drugs with potential activity against both species could be significant in the future.Furthermore,studies of susceptibility of both species to drugs could also help to know the different mechanisms of pathogenicity in humans displayed by T.cruzi that are absent in T.rangeli. | Ana Laura CIMADOR Emeli Luciana GALANTE Lucila Ibel MUNOZ Patricia Silvia ROMANO Antonella Denisse LOSINNO Maria Cristina VANRELL | 2019 | BIOCELL2019，43，1： | 1 |
| 4 | The Influence of Titanium Dioxid Modifications on Photocatalytic Oxidation of Lignin and Humic Acids显示文摘 | Elina Portjanskaja Kristina Stepanova Deniss Klauson | 2009 | Catalysis Today2009，144，12： | 1 |
| 5 | Improvement in microalgae lipid extraction using a sonication-assisted method显示文摘 | Aria Maria Pereira Nero Rafael Augusto Sotana de Souza Amanda Denisse Leon-Nino | 2013 | Renewable Energy2013，55，： | 1 |
| 6 | The influence of titanium dioxide modifications on photocatalytic oxidation of lignin and humic acids 显示文摘 | Elina Portjanskaja Kristina Stepanova Deniss Klauson | 2009 | Catalysis Today2009，144，12： | 1 |
| 7 | Com- munication and Representation as Elements in Mathematical Lit- eracy显示文摘 | Deniss R Thompson Michaele F Chappell | 2007 | Reading & Writing Quarterly2007，23，2： | 1 |
| 8 | Remote Sensing and GIS Technologies as Tools to Support Sustainable Management of Areas Devastated by Landslides显示文摘 | Noemi De La Ville Alejandro Chumaceiro Diaz Denisse Ramirez | 2002 | Environment Development and Sustainability2002，，2： | 1 |
| 9 | Spinal intability of defined by thd three column spine concept in adult spinal truma 显示文摘 | Deniss F | 1984 | Clin Orthop1984，189，： | 1 |
| 10 | Multifractal analysis of three large earthquakes in Chile:Antofagasta 1995,Valparaiso 1985,and Maule 2010显示文摘 | Denisse Pasten Diana Comte | 2013 | Springer Science+Business Media Dordrecht2013，10，57： | 1 |
| 11 | Effect of salinity on the thermoregulatory behavior of juvenile blue shrimp Litopenaeus stylirostris Stimpson显示文摘 | Denisse Re A Díaz F Valdez G | | 0，，06： | 1 |
| 12 | Finite data-size scaling of clustering in earthquake networks 显示文摘 | ABE Sumiyoshi PASTEN Denisse SUZUKI Norikazu | 2011 | Physica A Statistical Mechanics & Its Applications2011，390，7： | 1 |
| 13 | Diagnosis and Treatment of Lymphocutaneous Sporotrichosis: What Are the Options显示文摘 | Alexandro Borfifaz Denisse Vdzquez-Gonzdlez | 2013 | Current Fungal Infection Reports2013，7，3： | 1 |
| 14 | Communication and Representation as Elements in Mathematical Literacy 显示文摘 | Denisse R Thompson Michaele F Chappell | 2007 | Reading and Writing Quarterly2007，，23： | 1 |
| 15 | Infrared Absorption Study of N-H Bonds in Plasma-Deposited Silicon Oxynitride Films 显示文摘 | Denisse C M M Janssen J F M Habraken F H P M | 1988 | Applied Physics letters1988，52，16： | 1 |
| 16 | Investigation of the Effects of Salinity and Dietary Protein Level on Growth and Survival of Pacific White Shrimp, Litopenaeus vannamei显示文摘 | Luis R Martinez C Denisse A | 2007 | Journal ofthe World Aquaculture Society2007，38，4： | 1 |
| 17 | Universalities of earthquake-network characteristics显示文摘The scale-free and small-world properties are studied in detail for the complex earthquake networks constructed from the seismic data sets taken from California (USA), Japan, Iran and Chile. It is found that, in all these geographical regions, both the exponent / of the power-law connectivity distribution and the clustering coefficient C take the universal invariant values /≈1 and C≈0.85, respectively, as the cell size, which is the scale of coarse graining needed for construction of network, becomes larger than a certain value. A possible physical interpretation is given to the emergence of such remarkable invariance. | ABE Sumiyoshi PASTN Denisse MUOZ Víctor SUZUKI Norikazu | 2011 | Chinese Science Bulletin2011，56，34： | 0 |
| 18 | Photoinactivation of Escherichia coli using five photosensitizers and the same number of photons显示文摘Bacterial resistance is today a matter of great medical concern,so it is urgent to investigate alternatives to alleviate it.Photodynamic inactivation(PDI)is a method that has been endorsed to inactivate diferent pathogens,including bacteria,fungi and viruses.PDI is achieved by using a photosensitizer(PS)molecule which generates reactive oxygen species under visible or UV ra-diation.We use visible light and UV-A radiation to excite four commercial PSs(methylene blue,rose bengal,riboflavin and curcumin),and nanopartides synthesized in our laboratory.Despite these PSs having been thoroughly studied in the past by other research groups,in order to compare their effects in an appropriate way,we matched the number of photons they absorb.We found that methylene blue leads to the major inactivation of Escherichia coli.Furthermore,we evaluated the production of singlet axygen and hydroxyl radicals in the photoinactivation process. | Daniel Ortega-Zambrano Denisse Fuentes-López Hilda Mercado-Uribe | 2022 | Journal of Innovative Optical Health Sciences2022，15，6： | 0 |
| 19 | Assessing the Oxidative Stability of Commercial Chia Oil显示文摘 | Maria A. Grompone Bruno Irigaray Denisse Rodriguez Norma Sammain | 2013 | Journal of Food Science and Engineering2013，3，7： | 0 |
| 20 | Diversity and Inclusion:How Does ISO 30415 Affect a Company’s Business Model?显示文摘The International Standard Organization(ISO)published the first international certification,ISO 30415,regarding Human Resource Management-Diversity and Inclusion in May 2021.The new standard identifies a series of principles,roles,actions,policies,processes,and measures that support and develop diversity and inclusion in companies.The adoption of ISO 30415 influences the entire organization,triggering a rethinking of business practices and processes and the business model’s design.In this sense,the introduction of this standard creates great challenges and opportunities for organizations.The concepts of diversity and inclusion bring out a competitive advantage for organizations looking to increase innovation and enhance their resilience,sustainability,and reputation.Despite the growing interest shown by governments,private and public institutions,and companies toward diversity and inclusion issues,empirical research on the implementation of ISO 30415 in organizations is still limited.Our paper aims to narrow this research gap by answering the following question:How does the ISO 30415 certification affect a company’s business model?Empirical research based on the qualitative analysis of a single case study was conducted to answer this question.Findings show that the main changes in the business model can be reconducted into activities devoted to creating new capabilities,establishing new partnerships,advancing technologies,and implementing new processes to promote issues of diversity and inclusion.Notably,the new capabilities,technologies,processes,and partnerships did not cause a radical business model innovation in the case analysed but rather an incremental change in the business model since the concepts of diversity and inclusion were already strongly present in the company’s culture.This study offers valuable insights into the management diversity research area.Moreover,several practical implications emerge from results that improve entrepreneurs,managers,and governments’awareness of the benefits deriving from the adoption of ISO 30415. | Annalisa Sentuti Francesca Sgrò Federica Palazzi Gail Denisse Chamochumbi Diaz | 2023 | Chinese Business Review2023，22，1： | 0 |
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