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| 1 | Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization显示文摘Varicella-zoster virus(VZV) is a neurotropic alphaherpesvirus that causes chickenpox and shingles. ORF7 is an important virulence determinant of VZV in both human skin and nerve tissues,however, its specific function and involved molecular mechanism in VZV pathogenesis remain largely elusive. Previous yeast two-hybrid studies on intraviral protein-protein interaction network in herpesviruses have revealed that VZV ORF7 may interact with ORF53, which is a virtually unstudied but essential viral protein. The aim of this study is to identify and characterize VZV ORF53, and to investigate its relationship with ORF7. For this purpose, we prepared monoclonal antibodies against ORF53 and, for the first time, characterized it as a ~40 k Da viral protein predominantly localizing to the trans-Golgi network of the infected host cell. Next, we further confirmed the interaction between ORF7 and ORF53 by co-immunoprecipitation and co-localization studies in both plasmid-transfected and VZV-infected cells. Moreover, interestingly, we found that ORF53 lost its trans-Golgi network localization and became dispersed in the cytoplasm of host cells infected with an ORF7-deleted recombinant VZV, and thus ORF7 seems to play a role in normal subcellular localization of ORF53. Collectively, these results suggested that ORF7 and ORF53 may function as a complex during infection, which may be implicated in VZV pathogenesis. | Wei Wang Wenkun Fu Dequan Pan Linli Cai Jianghui Ye Jian Liu Che Liu Yuqiong Que Ningshao Xia Hua Zhu Tong Cheng | 2017 | Virologica Sinica2017，32，5： | 1 |
| 2 | The Pellet Enhanced Performance on the HL-2A Tokamak显示文摘 | DING Xuantong YANG Qingwei YAN Longwen ZHU Genliang CAO Zeng XIAO Zhenggui GAO Qingdi LONG Yongxing LIU Dequan LIU Yi ZHOU Yan PAN Yudong CUI Zhengying HUANG Yuan LIU Zetian SHI Zhongbing JI Xiaoquan XIAO Weiwen LIU Yong | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 1 |
| 3 | Recent Insights into Brassinosteroid Signaling in Plants: Its Dual Control of Plant Immunity and Stomatal Development显示文摘发信号的 Brassinosteroid (BR ) ,植物天生的免疫,和有气孔的开发是被像受体的 kinases 开始的三条小径。这评论在在提供某卓见进与表明小径的另外的受体交往的 BR 信号小径的分子的机制的植物免疫和有气孔的开发发信号的 BR 的角色集中于最近的调查结果。 | Xiangpei Kong Jiaowen Pan Guohua Cai Dequan Li | 2012 | Molecular Plant2012，5，6： | 1 |
| 4 | Overview of HL-2A Experiment Results显示文摘 | YANG Qingwei LIU Yong DING Xuantong YAN Longwen LIU Dequan XUAN Weiming CHEN Liaoyuan RAO Jun SONG Xianming CAO Zeng ZHANG Jinhua DUAN Xuru MAO Weicheng ZHOU Caipin PAN Chuanhong | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 1 |
| 5 | Divertor Experiments with MBI and Strong Gas Puffing on HL-2A显示文摘 | DUAN Xuru DING Xuantong YANG Qingwei YAN Longwen YAO Lianghua HONG Wenyu XUAN Weiming LIU Dequan CHEN Liaoyuan SONG Xianming ZHANG Jinhua CAO Zeng CUI Zhengying LI Wei LIU Yi PAN Yudong PAN Li ZHENG Yinjia ZHOU Yan MAO Weicheng LIU Yong 无 | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 0 |
| 6 | Siliconization for Wall Conditioning and Its Effect on Plasma Performance in HL-2A Tokamak显示文摘 | DUAN Xuru CAO Zeng CUI Chenghe CAI Xiao SUN Hongjuan DING Xuantong PAN Yudong WANG Mingxu YANG Qingwei SONG Xianming LIU Dequan LIU Yi JI Xiaoquan CUI Zhengying ZHOU Yan LIU Yong 无 | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 0 |
| 7 | Irradiation damage simulation of Zircaloy-4 using argon ions bombardment显示文摘To simulate irradiation damage,argon ion was implanted in the Zircaloy-4 with the fluence ranging from 1×10^(16) to 1×10^(17) cm^(-2),using accelerating implanter at an extraction voltage of 190 kV and liquid nitrogen temperature.Then the infuence of ar- gon ion implantation on the aqueous corrosion behavior of Zircaloy-4 was studied.The valence states of elements in the surface layer of the samples were analyzed using X-ray photoelectron spectroscopy(XPS).Transmission electron microscopy(TEM)was used to examine the microstructure of the argon-implanted samples.The potentiodynamic polarization technique was employed to evaluate the aqueous corrosion resistance of implanted Zircaloy-4 in 1 mol/L H_2SO_4 solution.It is found that there appear bubbles on the sur- face of the samples when the argon fluence is 1×10^(16) cm^(-2).The microstructure of argon-implanted samples changes from amor- phous to partial amorphous,then to polycrystalline,and again to amorphous.The corrosion resistance of implanted samples linearly declines with the increase of fuence approximately,which is attributed to the linear increase of the irradiation damage. | Dequan Peng Xinde Bai Feng Pan | 2008 | Journal of University of Science and Technology Beijing2008，15，3： | 0 |
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