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| 1 | Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD. | Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele | 2009 | World Journal of Gastroenterology2009，15，10： | 20 |
| 2 | Role of CT scans in the staging of esophageal and proximal gastric malignancies 显示文摘 | Maer Z Deveney CW Lopez KK | 1993 | Am Surg1993，1，5： | 1 |
| 3 | Hypogonadism,erectile dysfunction,and t ype 2 diabetes mellitus:what the clinician needs to know显示文摘 | Tamler R Deveney T | 2010 | Postgrad Med2010，122，6： | 1 |
| 4 | Evalua- ting LiBOB/lactone electrolytes in large-format lithium-ion cells based on nickelate and iron phosphate显示文摘 | Xu Kang Bridget Deveney Kamen Nechev | 2008 | J Electro- chem Soc2008，155，12： | 1 |
| 5 | Oncologic outcomes after resection of rectal cancer:Laparoscopic versus open approach显示文摘 | Sambasivan CN Deveney KE Morris KT | 2010 | Am J Surg2010，199，5： | 1 |
| 6 | Hypogonadism, erectile dysfunction, and type 2 diabetes meUitus:what the clinician needs to know显示文摘 | Tamler R Deveney T | 2010 | Postgrad Med2010，122，6： | 1 |
| 7 | Detection of recurrent rectosigmoid carcinoma:prospective evaluation of CT and clinical factors显示文摘 | McCarthy SM Baynes D Deveney K | 1985 | AJR1985，144，： | 1 |
| 8 | Reconstruc-tion of complex abdominal wall hernias using acellular humandermal matrix: a single institution experience 显示文摘 | Lin HJ Spoerke N Deveney C Martindale R | 2009 | Am JSurg2009，197，5： | 1 |
| 9 | Cognitive-behavioral therapy and the treatment of panic disorder:efficacy and strategies显示文摘 | Otto MW Deveney C | 2005 | J Clin Psychiatry2005，66，4： | 1 |
| 10 | establishment of human colonic epithelial cells in long-term culture 显示文摘 | Clifford W Deveney M D Leslie R | 1996 | J Surgi Research1996，64，： | 1 |
| 11 | Cognitive-behavioral therapy and the treat- ment of panic disorder:efficacy and strategies 显示文摘 | Otto MW Deveney C | 2005 | J Clin Psychia- try2005，66，： | 1 |
| 12 | Raman spectroscopy of calcified tissue 显示文摘 | Walton A G Deveney M J Koenig J L | 1970 | Calcified Tissue Research1970，6，1： | 1 |
| 13 | Validation of an HPLC method for the analysis of the charge heterogeneity of the recombinant monoclonal antibody IDEC-C2B8 after papain digestion显示文摘 | Moorhouse KG Nashabeh W Deveney J | 1997 | J Pharm Biomed Anal1997，16，4： | 1 |
| 14 | Reconstruction of complex ab- dominal wall hernias using acellular human dermal matrix : a single insti- tution experience 显示文摘 | Lin H J Spoerke N Deveney C | 2009 | Am J Surg2009，197，5： | 1 |
| 15 | Revisional bariatric surgery for failed restrictive procedures显示文摘 | Brian A. Coakley Clifford W. Deveney Donn H. Spight Sarah K. Thompson David Le Blair A. Jobe Bruce M. Wolfe Donald B. McConnell Robert W. O’Rourke | 2008 | Surgery for Obesity and Related Diseases2008，，5： | 1 |
| 16 | Anomalous Release of Hydrophilic Drugs from Poly(ε-Caprolactone) Matrices 显示文摘 | Rosenberg R Deveney W Siegel S | 2007 | Mol Pharmac2007，4，6： | 1 |
| 17 | Evaluating LiBOB/Lactone elec- trolytes in large-format lithium-ion cells based on nickelate and iron phosphate显示文摘 | XU K DEVENEY B NECHEV K | 2008 | Journal of the Electrochemical Society2008，155，12： | 1 |
| 18 | Factors contributing to leakage of colonic anastomoses 显示文摘 | Schrock TR Deveney CW Dunphy JE | 1973 | Ann Surg1973，177，5： | 1 |
| 19 | Improved treatment of intra-abdominal absecss显示文摘 | Deveney CW Lurie K Deveney KE | 1988 | Arch Surg1988，123，9： | 1 |
| 20 | Reconstruction of-complex abdominal wall hernias using acellular human dermal matrix: a single institution experience显示文摘 | Lin HJ Spoerke N Deveney C | 2009 | Am J Surg2009，197，5： | 1 |
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