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| 1 | Managements of osteoporotic vertebral compression fractures:A narrative review显示文摘Osteoporotic vertebral compression fractures(OVCFs)are the most common fragility fracture and significantly influence the quality of life in the elderly.Currently,the literature lacks a comprehensive narrative review of the management of OVCFs.The purpose of this study is to review background information,diagnosis,and surgical and non-surgical management of the OVCFs.A comprehensive search of PubMed and Google Scholar for articles in the English language between 1980 and 2021 was performed.Combinations of the following terms were used:compression fractures,vertebral compression fractures,osteoporosis,osteoporotic compression fractures,vertebroplasty,kyphoplasty,bisphosphonates,calcitonin,and osteoporosis treatments.Additional articles were also included by examining the reference list of articles found in the search.OVCFs,especially those that occur over long periods,can be asymptomatic.Symptoms of acute OVCFs include pain localized to the mid-line spine,a loss in height,and decreased mobility.The primary treatment regimens are pain control,medication management,vertebral augmentation,and anterior or posterior decompression and reconstructions.Pain control can be achieved with acetaminophen or nonsteroidal anti-inflammatory drugs for mild pain or opioids and/or calcitonin for moderate to severe pain.Bisphosphonates and denosumab are the first-line treatments for osteoporosis.Vertebroplasty and kyphoplasty are reserved for patients who have not found symptomatic relief through conservative methods and are effective in achieving pain relief.Vertebroplasty is less technical and cheaper than kyphoplasty but could have more complications.Calcium and vitamin D supplementation can have a protective and therapeutic effect.Management of OVCFs must be combined with multiple approaches.Appropriate exercises and activity modification are important in fracture prevention.Medication with different mechanisms of action is a critical long-term causal treatment strategy.The minimally invasive surgical interventions such as vertebroplasty and kyphoplasty are reserved for patients not responsive to conservative therapy and are recognized as efficient stopgap treatment methods.Posterior decompression and fixation or Anterior decompression and reconstruction may be required if neurological deficits are present.The detailed pathogenesis and related targeted treatment options still need to be developed for better clinical outcomes. | Devon Patel Jiayong Liu Nabil A Ebraheim | 2022 | World Journal of Orthopedics2022，13，6： | 5 |
| 2 | The Association of Pain With Protein Inflammatory Biomarkers: A Review of the Lit- erature显示文摘 | Devon H A Piano M R Rosenfeld A G | 2014 | Nurs Res2014，63，1： | 1 |
| 3 | Effects of core-shell latex morphology on film forming behavior显示文摘 | Devon M T Gardon J L Rudin A | 1990 | J Appl Polym Sci1990，39，10： | 1 |
| 4 | Cavity ring-down optical spectrometer for absorption measurements using pulsed laser sources 显示文摘 | O' Keefe A Devon G D | 1985 | Review of Seientific Instruments(S0034-6748)1985，59，12： | 1 |
| 5 | Cavity ring-down optical spectrometer for absorption measurements using pulsed laser sources显示文摘 | O'keefe A Devon G D | 1985 | Rev Sci Instrum1985，59，12： | 1 |
| 6 | Symptoms of acute coronary syn- dromes: are there gender differences? A review of the lit- erature 显示文摘 | DeVon H A Zerwic J J | 2002 | Heart Lung2002，31，4： | 1 |
| 7 | Effects of core-shell latex morphology on film forming behavior 显示文摘 | Devon M T Gardon J L Rudin A | 1990 | J Appl Polym Sci1990，39，10： | 1 |
| 8 | Synthesis of acrylate and methacrylate block copolymers using atom transfer radical polymerization 显示文摘 | Devon A Shipp Wang Jenlung | 1998 | Macromolecules1998，31，： | 1 |
| 9 | Measurosof psychological stress and physical health in family care-givers of stroke survivors:A literature review显示文摘 | SabanK L Sherwood P R DeVon H A | 2010 | J Neu-rosci Nurs2010，42，3： | 1 |
| 10 | 显示文摘 | Christy D P Richard F B Devon A S | 2008 | J Polym Sci Part A: Polym Chem2008，46，21： | 1 |
| 11 | Modified Atmosphere Packaging of Fresh Produce显示文摘 | Adel A Kader | 1988 | Food Technology1988，42，9： | 1 |
| 12 | Insensitive acetylcho linesterase and esterase polymorphism in susceptible and resistance populations of the tobacco whitefly, Bemisia tabaci (Genn)显示文摘 | BYRNE F J DEVON SH IRE A L | 1993 | Pesticide Biochemistry and Physiology1993，45，： | 1 |
| 13 | Symptom Clusters in Acute Myocardial Infarction: A Secondary Data Analysis显示文摘 | ] Ryan C J DeVon H A Home R | 2007 | Nurs Res2007，56，2： | 1 |
| 14 | Treatment see- king for acute myocardial infarction symptoms: diffe- rences in delay across sex and race显示文摘 | Zerwie J J Ryan C J DeVon H A | 2003 | Nurs Res2003，52，3： | 1 |
| 15 | Symptoms across the continuum of acute coronary syndromes: differences be- tween women and men显示文摘 | DeVon H A Ryan C J Ochs A L | 2008 | Am J Grit Care2008，17，1： | 1 |
| 16 | Concerted assembly and cloning of multiple DNA segments using in vitro sitespecific recombination:functional analysis of multisegment expression clones显示文摘 | David L C Steven A T Devon R N B | 2004 | Genome Research2004，，14： | 1 |
| 17 | Cavity ring-down optical spectrometer for absorption measurements using pulsed laser sources 显示文摘 | O' Keefe A Devon G D | 1985 | Review of Scientifie Instruments(S0034-6748)1985，59，12： | 1 |
| 18 | Modified atmosphere packaging of fresh produce显示文摘 | Devon Z Adel A K | 1998 | Food Technology1998，，9： | 1 |
| 19 | Cavity ring-down optical spectrometer for absorption measurements using pulsed laser sources显示文摘 | O'KEEFE A DEVON G D | 1985 | Rew Sci Instrum1985，9，12： | 1 |
| 20 | Modified atmosphere packaging of flesh produce 显示文摘 | DEVON Z KADER A A | 1988 | Food Technology1988，42，9： | 1 |
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