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| 1 | Impact of body composition on survival and morbidity after liver resection in hepatocellular carcinoma patients显示文摘Background: Hepatocellular carcinoma is the most common innate liver tumor. Due to improved surgical techniques, even extended resections are feasible, and more patients can be treated with curative intent. As the liver is the central metabolic organ, preoperative metabolic assessment is crucial for risk stratification. Sarcopenia, obesity and sarcopenic obesity characterize body composition and metabolic status. Here we present the impact of body composition on survival after liver resection in patients with hepatocellular carcinoma. Methods: A retrospective database analysis of 70 patients who were assigned for liver resection due to hepatocellular carcinoma was conducted. For assessment of sarcopenia and obesity, skeletal muscle surface area was measured at lumbar vertebra 3 level(L3) in preoperative four-phase contrast enhanced abdominal CT scans, and L3 muscle index and body fat percentage were calculated. Results: Univariate analysis comparing the survival curves using the score test demonstrated superior postoperative overall survival for sarcopenic( P = 0.035) and sarcopenic obese( P = 0.048) patients as well as a trend favoring obese( P = 0.130) subjects. Whereas multivariate analysis could not identify significant difference in postoperative survival regarding sarcopenia, obesity or sarcopenic obesity. Only large tumor size, multifocal disease and male gender were risk factors for long-term survival. Conclusions: Sarcopenia, obesity and sarcopenic obesity are indeed no risk factors for poor postoperative survival in this study. Our data do not support the evaluation of sarcopenia, obesity and sarcopenic obesity before liver resection in hepatocellular carcinoma patients. | Andreas Kroh Diane Uschner Toine Lodewick Roman M Eickhoff Wenzel Sch?ning Florian T Ulmer Ulf P Neumann Marcel Binneb?sel | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 5 |
| 2 | Strategies for the purification and on-column cleavage of glutathione-S-transferase fusion target proteins 显示文摘 | Eshaghi S Urbig T | 2002 | J Chromatogr B Analyt Technol Biomed Life Sci2002，769，1： | 1 |
| 3 | Comparison of Three Management Strategies for Patients With Atypical Squamous Cells of Undetermined Significance: Baseline Results From a Randomized Trial显示文摘 | Diane S Mark S Robert T | 2001 | Journal of the National Cancer Institute2001，93，4： | 1 |
| 4 | Augmented expression of cardiotrophin-1 and its receptor component,gp130,in both left and right ventricles after myocardial infarction in the rat显示文摘 | Tsdeshi A Yoshihito T Diane P | | 0，，： | 1 |
| 5 | Strategies for the puri- fication and on-column cleavage of glutathione-S- transferase fusion target proteins 显示文摘 | Dian C Eshaghi S Urbig T | 2002 | Journal of Chroma- tography B2002，769，1： | 1 |
| 6 | Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe 显示文摘 | Diane R W Maximillian T F | 2005 | Cancer Research2005，65，12： | 1 |
| 7 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 8 | Low-density lipoprotein antioxidant activity of phenolic compounds and polyphenol oxidase activity in selected clingstone peach cultivars显示文摘 | Chang S Christine T Edwin N F Diane M B | | 0，，： | 1 |
| 9 | β-cell Mass dynamics in Zucker diabetic fatty rats: Rosiglitazone prevents the rise in net cell death显示文摘 | Diane T Finegood M Dawn McArthur | 2001 | Diabetes2001，50，： | 1 |
| 10 | Overview of the Radiometric and Biophysical Performance of the MOD1S Vegetation Indices显示文摘 | Huele A Dian K Miura T | 2002 | Remote Sensing of Enviroment2002，83，： | 1 |
| 11 | Pharmacokinetics and safety of levofloxacin in patients with human immunodefieieney virus infection显示文摘 | Diane S Happy A Andrew T | 1994 | Antimierob Agents Chemother1994，38，4： | 1 |
| 12 | Rheology and melt characterization of low-fat and full fat MoZzarella cheese made from microfluidized milk显示文摘 | Diane L V Michael H T Edyth L M | 2007 | Food Science and Technology2007，40，1： | 1 |
| 13 | Meta-Analysis of the Efficacy of Hormone Replacement Therapy in Treating and Preventing Osteoporosis in Postmenopausal Women显示文摘 | George W Peter T Beverley S Gordon G Joan P Nicole Z Vivian R David H Diane O Ann C | 2002 | Endocrine Reviews2002，23，4： | 1 |
| 14 | Methyl jasmonate induces traumatic resin ducts, terpenoid resin biosynthesis, and terpenoid accumulation in developing xylem of Norway spruce stems显示文摘 | Diane M Dorothea T Jonathan G | 2002 | Plant Physiol2002，129，： | 1 |
| 15 | Cell production in in- jured vocal fold: a rat stady显示文摘 | Ichiro T Tomoko T Diane B | 2006 | Ann Otol Rhinol Laryngol2006，115，： | 1 |
| 16 | Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials 显示文摘 | Linda M M Diane S | 1987 | J Immunol Methods1987，102，： | 1 |
| 17 | Global diversifi- cation, Industrial Diversification, and Firm Value 显示文摘 | T David J D Diane K D Keven Y | 2002 | The Journal of Finance2002，，5： | 1 |
| 18 | Integrating evidence-based practice in nurse practice education显示文摘 | MARGARET A ELIZABETH A DIANE O T | 2004 | Clin Pract Guildlines2004，16，12： | 1 |
| 19 | Short Sleep Duration ls Associated with Reduced Leptin,Elevated Ghrelin,and Increased Body显示文摘 | Shahrad T Ling L Diane A | 2004 | Mass Index Plos Med2004，1，3： | 1 |
| 20 | Augmented expression of cardiotrophin-1 and its receptor component,gp130,in both left and right ventricles after myocardial infarction in the rat显示文摘 | Yoshihito T Diane P | 2000 | J Mol Cell Cardiol2000，32，： | 1 |
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