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| 1 | TME术前短程放疗后化疗对比术前放化疗联合术后辅助化疗治疗局部晚期直肠癌(RAPIDO研究)—一项随机、开放的Ⅲ期临床试验显示文摘背景:全身复发仍然是局部晚期直肠癌患者需要面临的难题。该研究是采用短程放疗后行化疗和延迟手术对比术前诱导治疗后直接手术疗效的临床试验(the Rectal cancer And Preoperative Induction therapy followed by Dedicated Operation,RAPIDO),旨在不影响局部控制效果的前提下减少远处转移。方法:在这项多中心、随机、开放的Ⅲ期试验中,参与者来自于荷兰、瑞典、西班牙、斯洛文尼亚、丹麦、挪威和美国的共54个医学中心。纳入患者年龄在18岁及以上,ECOG评分为0~1分,且为经活检确诊局部晚期原发直肠腺癌的初诊患者,盆腔MRI评估为高危(至少符合一项标准:cT4a或cT4b,壁外血管侵犯,cN2,直肠系膜筋膜受累,或侧方淋巴结增大)。患者具备化疗适应证,并可在随机分组前5周内完成分期评估。 | 李来元 张维胜 BAHADOER R R DIJKSTRA E A VAN ETTEN B | 2021 | 结直肠肛门外科2021，27，1： | 72 |
| 2 | 13C andl5N natural abundance of the soil microbial biomass显示文摘 | Dijkstra P Ishizu A Doucett R Hart S C Schwartz E Menyailo O V Hungate B A | 2006 | Soil Biology & Biochemistry2006，38，： | 1 |
| 3 | Smallest detectabledifference in outcome variables related to painful restriction ofthe temporomandibular joint显示文摘 | Kropmans TJ Dijkstra PU Stegenga B | 1999 | J Dent Res1999，78，3： | 1 |
| 4 | cd显示文摘 | Nardini M Dijkstra B W | 1999 | Current Opinion in Structural Biology1999，9，： | 1 |
| 5 | Relative cont ributions of NOS isoforms during experimental colitis:endot helial-derived NOS maintains mucosal integrity显示文摘 | Vallance BA Dijkstra G Qiu B | 2004 | Am J Physiol Gast rointest Liver Physiol2004，287，4： | 1 |
| 6 | Bacterial biocatalysis:Molecular biology,three-dimensional structures,and biotechnological applications of lipases显示文摘 | Jaeger K-E Dijkstra B W Reetz M T | 1999 | Annual Review of Microbiology1999，53，1： | 1 |
| 7 | The role of arginine 47 in the cyclization and coupling reactions of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 implications for product inhibition and product specificity显示文摘 | VEEN BA V UITDEHAAG J C DIJKSTRA B W | 2000 | Eur J Biochem2000，267，： | 1 |
| 8 | CO2 elicits long-term decline in nitrogen fixation显示文摘 | Hungate B Stiling P Dijkstra P | 2004 | Science2004，304，： | 1 |
| 9 | Mutations convertion cyclodextrin glycosyltransferase from a transglycosylase into a starch hydrolase显示文摘 | LEEMHUIS H DIJKSTRA B W | 2002 | FEBS Lett2002，514，： | 1 |
| 10 | Three new genera of damselflies ( Odonata: Chlorocyphidae, Platycnemididae)显示文摘 | DIJKSTRA K D B | 2013 | International ]our- nal of Odonatology2013，16，3： | 1 |
| 11 | Relative contributions of NOS isotbrms during experimental colitis: endothelial-derived NOS maintains mucosal integrity 显示文摘 | Vallance BA Dijkstra G Qiu B | 2004 | Am J Physiol Gastrointest Liver Physio12004，287，4： | 1 |
| 12 | Multiple sclerosis and vitamin D:an update显示文摘 | VanAmerongen B M Dijkstra C D Lips P | 2004 | Eur J Clin Nutr2004，58，8： | 1 |
| 13 | Analog line driver with adaptive impedance matching显示文摘 | Nauta B Dijkstra M B | 1998 | IEEE J Sol Sta Circ1998，33，12： | 1 |
| 14 | Groningen temporomandibular total joint prosthesis: an 8-year longitudinal follow-up on function and pain显示文摘 | Schuurhuis JM Dijkstra PU Stegenga B | 2012 | J Craniomaxillofac Surg2012，40，8： | 1 |
| 15 | Detection of gait and postures using a miniaturized iriaxial accelerometer-based system: Accuracy in patients with mild to moderate Parkin- son's disease 显示文摘 | Dijkstra B Kamsma YP Zijlstra W | 2010 | Arch Phys Med Rehabil2010，91，8： | 1 |
| 16 | Review Clinical Application of Electrical Impedance Tomography显示文摘 | Dijkstra A M Brown B H Leathard A D | 1993 | Journal of Medical Engineering & Technology1993，17，3： | 1 |
| 17 | 显示文摘 | Zeeman R Dijkstra P J Van Wachem P B | 1999 | Biomaterials1999，20，： | 1 |
| 18 | Stomatal acclimation to increased CO2 concentration in a Florida scrub oak species Quereus myrifolia Willd显示文摘 | LODGE R J DIJKSTRA P DRAKE B G | | 0，，： | 1 |
| 19 | The value of sentinel node mapping for staging melanoma显示文摘 | Dijkstra B Hill A Kelly L | 2001 | Ir Med J2001，94，7： | 1 |
| 20 | Global diversity of dragonflies (Odonata) in freshwater 显示文摘 | Kalkman V J Clausnitzer V Dijkstra K B | 2008 | Hydrobiologia2008，595，1： | 1 |
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