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| 1 | Exploring polyamines:Functions in embryo/fetal development显示文摘Polyamines such as putrescine, spermidine, spermine and agmatine are aliphatic polycationic compounds present in all living cells, and are derived from amino acids, intestinal bacteria, exfoliated enterocytes and supported from diet. Polyamines as the key compounds play essential role in cell proliferation, growth and differentiation. They also exert significant effects on embryonic development,implantation, embryonic diapause, placentation, angiogensis and fetal development. This review paper summarizes the functions of polyamines and embryo/fetus development and its regulatory mechanism which should help to provide some evidences for clinic. | Tarique Hussain Bi'e Tan Wenkai Ren Najma Rahu Dildar Hussain Kalhoro Yulong Yin | 2017 | Animal Nutrition2017，，1： | 6 |
| 2 | Lipase inhibitory activity of Lagenaria siceraria fruit as a strategy to treat obesity显示文摘Objective:To explore pancreatic lipase inhibitory activity under different extraction conditions in order to track the most potent extract.Methods:The methanolic extract and its fractions in solvents of increasing polarity,ether,chloroform,ethyl acetate,n-butanol and water,were made through cold maceration.Extracts in ethanol,ethyl acetate,acetone and chloroform were similarly prepared.Aqueous extract was prepared through hot decoction method.A reported method was used to determine lipase inhibitory activity of extracts and fractions over wide ranges of concentrations.Results:The extracts and fractions exhibited concentration dependent activity.The IC50(μg/mL)values of methanolic,ethanolic,chloroform,ethyl acetate,acetone,ethyl acetate(after washing with water)and aqueous decoction were 293.40,266.47,157.59,182.12,352.34,257.00,and 190.00,respectively.The activity of chloroform,ethyl acetate and aqueous extracts were close to that of the drug orlistat(IC50 146μg/mL).Out of the fractions of the methanolic extract,the chloroform fraction was most active(IC50 189.6μg/mL).The order of inhibitory activity of the fractions was as follows:chloroform>ether>n-butanolic>aqueous>ethyl acetate.The GC/MS analysis of the most active chloroform faction showed the presence of hexadecanoic acid,methyl hexadecanoate,isopropyl palmitate,methyl 9,12-octadecadienate,and methyl 9,12,15-octadecatrienoate.Conclusions:The study suggests that Lagenaria siceraria has potential to inhibit pancreatic lipase activity,suppressing lipid digestion and thereby diminishing entry of lipids into the body.Regular intake of aqueous decoction of the fruit may therefore be recommended for control of obesity.Fatty acids and their esters may play role as inhibitors of lipase. | Maria Maqsood Dildar Ahmed Iqra Atique Wajeeha Malik | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，3： | 3 |
| 3 | H3N2亚型犬流感病毒与伪中间葡萄球菌的体外共感染研究显示文摘为了研究犬流感病毒(CIV)与伪中间葡萄球菌(Sp)对犬肾细胞(MDCK)的共感染作用,利用犬流感病毒、伪中间葡萄球菌和犬肾细胞,建立并优化了病毒-细菌体外细胞共感染模型。试验分4组:病毒单独感染组(CIV)、细菌单独感染组(Sp)、感染病毒后第12小时再感染细菌组(CIV/Sp)及空白对照组(C)。结果显示,病毒感染后第24小时,CIV/Sp组的细胞毒性为39.7%,极显著高于CIV组和Sp组(P<0.001);CIV/Sp组病毒RNA载量显著低于CIV组(P<0.001)。细菌黏附和侵袭试验表明,细菌感染后第4小时,CIV/Sp的黏附和侵袭量极显著高于Sp组(P<0.001),侵袭量升高20倍。细菌感染后第6小时,CIV/Sp组IL-6、TNF-α的表达量均极显著高于其他3组(P<0.001)。研究结果表明,犬流感病毒的预感染增强了伪中间葡萄球菌对体外培养细胞的继发感染。 | 梁姗 谢星 高珊珊 Dildar Hussain Kalhoro 王永山 刘永杰 | 2016 | 中国兽医科学2016，46，12： | 3 |
| 4 | Chemical constituents of Buxus sempervirens显示文摘 | Atta-ur-Rahman Dildar Ahmed M Iqbal Choudhary | 1988 | Planta Med1988，54，2： | 1 |
| 5 | The Serum protein and lipid oxidation marker levels in Alzheimer's disease and effects of cholinesterase inhibitors and antipsychotic drugs therapy显示文摘 | Sinem F Dildar K Gfikhan E | 2010 | Curr Alzheimer Res2010，7，： | 1 |
| 6 | The serum protein and lipid oxi-dation marker levels in alzheimer's disease and effects of cholines-terase inhibitors and antipsychotic drugs therapy 显示文摘 | Sinem F Dildar K Gokhan E | 2010 | Current Al-zheimer Research2010，7，5： | 1 |
| 7 | The serum protein and lipid oxidation marker levels in Alzheimer's disease and effects of cholinesterase inhibitors and antipsychotic drugs therapy显示文摘 | Sinem F Dildar F G(o)khan E | | 0，，05： | 1 |
| 8 | Nucleation of Boron-Nitrogen on Transition Metal Surface:A First-Principles Investigation显示文摘Boron nitrogen(BN)monolayer has attracted considerable attention because of their suc-cessful incorporation with graphene based nanodevices.However,many important aspects of the growth mechanisms are still not well explored.Using density functional theory(DFT)calculations,we found that Cu(111)surface is more suitable to be used as a substrate to grow BN monolayer compared with Ni(111)surface.Moreover,we explored that one-dimensional(1D)BN chain configuration is dominant to the two-dimensional(2D)BN ring formation from one pair to five BN pairs deposited on Cu(111)surface.Energetically stable structure transformation of BN monolayer from 1D BN chain to 2D BN ring occurs when the number of pairs is n>5.It is suggested that,as the number of BN pairs increases the energetically stable structures achieve. | Dildar Ahmed Erjun Kan | 2018 | Chinese Journal of Chemical Physics2018，31，3： | 1 |
| 9 | Indoor air pollu- tion from particulate matter emissions in different house holds in rural areas of Bangladesh显示文摘 | Bilkis A B Samir K P Dildar H | 2009 | Building and En- vironment2009，44，5： | 1 |
| 10 | Indoor air pollution from particulate matter emissions in different households in rural areas of Bangladesh 显示文摘 | Begum B A Paul S K Dildar Hossain M | 2009 | Building and Environment2009，44，5： | 1 |
| 11 | Intelligent Breast Cancer Prediction Empowered with Fusion and Deep Learning显示文摘Breast cancer is the most frequently detected tumor that eventually could result in a significant increase in female mortality globally.According to clinical statistics,one woman out of eight is under the threat of breast cancer.Lifestyle and inheritance patterns may be a reason behind its spread among women.However,some preventive measures,such as tests and periodic clinical checks can mitigate its risk thereby,improving its survival chances substantially.Early diagnosis and initial stage treatment can help increase the survival rate.For that purpose,pathologists can gather support from nondestructive and efficient computer-aided diagnosis(CAD)systems.This study explores the breast cancer CAD method relying on multimodal medical imaging and decision-based fusion.In multimodal medical imaging fusion,a deep learning approach is applied,obtaining 97.5%accuracy with a 2.5%miss rate for breast cancer prediction.A deep extreme learning machine technique applied on feature-based data provided a 97.41%accuracy.Finally,decisionbased fusion applied to both breast cancer prediction models to diagnose its stages,resulted in an overall accuracy of 97.97%.The proposed system model provides more accurate results compared with other state-of-the-art approaches,rapidly diagnosing breast cancer to decrease its mortality rate. | Shahan Yamin Siddiqui Iftikhar Naseer Muhammad Adnan Khan Muhammad Faheem Mushtaq Rizwan Ali Naqvi Dildar Hussain Amir Haider | 2021 | Computers, Materials & Continua2021，，4： | 1 |
| 12 | Indoor air pollution from particulate matter emissions in different house holds in rural areas of Bangladesh 显示文摘 | Bilkis A Begum Samir K Paul M Dildar Hossain | 2009 | Building and Environment2009，44，5： | 1 |
| 13 | Chemical constituents of Buxus sempenirens显示文摘 | Atta-ur-Rahman Dildar Ahmed 1988 | 1988 | Planta Medica1988，，： | 1 |
| 14 | Cucurbitacin glucosides from Citrullus colocynthis显示文摘 | Durey Nayab Dildar Ali Nuzhat Arshad Abdul Malik M. Iqbal Choudhary Zaheer Ahmed | 2006 | Natural Product Research2006，，5： | 1 |
| 15 | Total antioxidant status and markers of oxidative stress in subjects with normal or impaired glucose regulation (IFG, IGT) in diabetic patients显示文摘 | Gulcan Guntas Korkmaz Dildar Konukoglu Eda Merve Kurtulus Hulya Irmak Murat Bolayirli Hafize Uzun | 2013 | Scandinavian Journal of Clinical & Laboratory Investigation2013，，8： | 1 |
| 16 | The effects of hormone replacement therapy on lipid peroxidation and antioxidant status显示文摘 | Ozden S Dildar K Kadir YH | 2001 | Maturitas2001，38，2： | 1 |
| 17 | Comparative analysis of phenolics,flavonoids,and antioxidant and antibacterial potential of methanolic,hexanic and aqueous extracts from adiantum caudatum leaves显示文摘 | DILDAR A MEHBOOB K M RAMSHA S | 2015 | Antioxidants2015，4，2： | 1 |
| 18 | Indoor air pollution from particulatematteremissionsin different households in rural areas of Bangladesh显示文摘 | BILKIS AB SAMIR K P DILDAR H M et a l | 2009 | Building and Environment2009，44，5： | 1 |
| 19 | Roman Urdu News Headline Classification Empowered with Machine Learning显示文摘Roman Urdu has been used for text messaging over the Internet for years especially in Indo-Pak Subcontinent.Persons from the subcontinent may speak the same Urdu language but they might be using different scripts for writing.The communication using the Roman characters,which are used in the script of Urdu language on social media,is now considered the most typical standard of communication in an Indian landmass that makes it an expensive information supply.English Text classification is a solved problem but there have been only a few efforts to examine the rich information supply of Roman Urdu in the past.This is due to the numerous complexities involved in the processing of Roman Urdu data.The complexities associated with Roman Urdu include the non-availability of the tagged corpus,lack of a set of rules,and lack of standardized spellings.A large amount of Roman Urdu news data is available on mainstream news websites and social media websites like Facebook,Twitter but meaningful information can only be extracted if data is in a structured format.We have developed a Roman Urdu news headline classifier,which will help to classify news into relevant categories on which further analysis and modeling can be done.The author of this research aims to develop the Roman Urdu news classifier,which will classify the news into five categories(health,business,technology,sports,international).First,we will develop the news dataset using scraping tools and then after preprocessing,we will compare the results of different machine learning algorithms like Logistic Regression(LR),Multinomial Naïve Bayes(MNB),Long short term memory(LSTM),and Convolutional Neural Network(CNN).After this,we will use a phonetic algorithm to control lexical variation and test news from different websites.The preliminary results suggest that a more accurate classification can be accomplished by monitoring noise inside data and by classifying the news.After applying above mentioned different machine learning algorithms,results have shown that Multinomial Naïve Bayes classifier is giving the best accuracy of 90.17%which is due to the noise lexical variation. | Rizwan Ali Naqvi Muhammad Adnan Khan Nauman Malik Shazia Saqib Tahir Alyas Dildar Hussain | 2020 | Computers, Materials & Continua2020，，11： | 0 |
| 20 | Impact of numerous larval diets on the biology of pink bollworm Pectinophora gossypiella(Saunders)(Lepidoptera:Gelechiidae)under laboratory conditions显示文摘Background Pink bollworm,Pectinophora gossypiella(Saunders)(Lepidoptera:Gelechiidae)has become a poten-tial pest of cotton by causing substantial yield losses around the world including Pakistan.Keeping in view the facts like limited research investigations,unavailability,and high cost of artificial diet’s constituents and their premixes,the present research investigations on the dietary aspect of P.gossypiella were conducted.The larvae of P.gossypiella were reared on different diets that were prepared using indigenous elements.The standard/laboratory diet com-prised of wheat germ meal 34.5 g,casein 30.0 g,agar–agar 20.0 g,sucrose 10.0 g,brewer’s yeast 5.0 g,α-cellulose 1.0 g,potassium-sorbate1.5 g,niplagin 0.5 g,decavitamin 0.01 g,choline-chloride 0.06 g,maize-oil 3.30 g,honey 2.0 g,and water 730.0 mL.Alternatives to cotton bolls and wheat germ meal were okra seed sprouts,okra fruit,cottonseed meal,and okra seed meals,which were included in the study to introduce an efficient and economic mass-rearing system.Results The larval development completed in 19.68d±0.05 d with a weight of 20.18mg±0.20 mg at the fourth instar fed on the cottonseed meal-based diet instead of wheat germ meal based diet.On the same diet,84.00%±4.00%,17.24 mg±0.03 mg,and 7.76d±0.06 d were recorded as pupae formation,pupal weight,and pupal duration,respectively.Adult emergence,76.00%±1.00%was recorded from pupae collected from larvae raised on cottonseed meal-based diet.These male and female moths lived for 40.25d±0.10 d,and 44.34d±0.11 d,respectively.Females deposited 21.28±0.04 eggs per day with the viability of 65.78%±0.14%.The larval mortal-ity at the fourth instar was 37.20%±1.36%and malformed pupation of 12.00%±1.41%was recorded.Replacement of wheat germ meal with that of local meals(cottonseed and okra seed)in the standard laboratory diet has saved 463.80 to 467.10 PKR with 1.62 to 1.63 cost economic returns,respectively.Conclusion This research is of novel nature as it provides a concise and workable system for the economic and suc-cessful rearing of P.gossypiella under laboratory conditions. | AKHTAR Shamim ARIF Muhammad Jalal GOGI Muhammad Dildar HAQ Imran-ul | 2024 | Journal of Cotton Research2024，7，1： | 0 |
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