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| 1 | Thymidine kinase gene mutation leads to reduced virulence of pseudorabies virus显示文摘To explore correlation between the tk gene structure of pseudorabies virus (PRV) and its virulence, to study the effect of the gene mutation on PRV biological properties, and to investigate mechinism of reduced virulence, thymidine kinase (TK)-deficient mutant of pseudorabies virus strain Hubei (PRV HB) was isolated by selection for resistance to 5-bromodeoxyuridine. The tk genes of PRV HB and its TK mutant were cloned and sequenced. 1587 base pairs of the tk gene and flanking regions of wild-type (wt) virus were sequenced, which included an open reading frame (ORF) of 1098 bp encoding a protein of 366 amino acids. The ORF contained two 137-bp repeated sequences, which were connected by an adenosine. 1458 bp of the tk and flanking regions of TK- mutant were sequenced. Analysis of the tk gene sequence of TK mutant indicated that one of 137 bp repeated sequence and the connecting adenosine in the tk gene of the wt virus was deleted and a repeated sequence of 8 nucleotides (GCGCGCC) was inserted. All | Pan, ZS Zhang, CY Ding, JH Min, P | 2001 | Chinese Science Bulletin2001，46，23： | 2 |
| 2 | Postoperative hormone replacement therapy for epithelial ovarian cancer patients: a systematic review and meta-analysis显示文摘 | Li D Ding CY Qiu LH | 2015 | Gynecol Oncol2015，139，2： | 1 |
| 3 | Chinese midwives experience of providing continuity of care to labouring women显示文摘 | Gu CY Zhang Z Ding Y | 2011 | Mid- wifery2011，27，2： | 1 |
| 4 | Hepatitis B virus basal core promoter mutations A1762T/G1764A are associated with genotype C and a low serum HBsAg level in chroni cally-infected HBeAg positive chinese patients显示文摘 | Yan CH Zhao CY Ding H | 2012 | Antivi ral Res2012，96，2： | 1 |
| 5 | Enhancement of adsorption and photocatalytic activity of TiO2 by using carbon nanotubes for the treatment of azo dye显示文摘 | Yu Y Yu JC Chan CY Che YK Zhao JC Ding L | 2005 | Appl Catal B-Environ2005，61，12： | 1 |
| 6 | Expression of multidrug resistance type 1 gene( MDR1 ) P-glycoprotein in intractable epilepsy with different aetiologies:a double-labelling and electron microscopy study 显示文摘 | Ding CY Li GM Martin E | 2006 | Neurol Sci2006，27，： | 1 |
| 7 | Relation of abnormal gallblad- der arterioles to gallbladder emlptying in patients with gall- stone and diabetes mellitus显示文摘 | Ding X Gong JP Lu CY | 2004 | Hepatobiliary Pancreat Dis Int2004，3，： | 1 |
| 8 | Repair of uterine rupture in twin gestation after laparoscopic cornual resection 显示文摘 | Liao CY Ding DC | 2009 | J Minim Invasive Gynecol2009，16，4： | 1 |
| 9 | Early retinal arteriolar changes and peripheral neuropathy in diabetes显示文摘 | Ding J Cheung CY Ikram MK | 2012 | Diabetes Care2012，35，5： | 1 |
| 10 | A-type granite belts of two chemical sub-groups in central eastern China:Indication of ridge subduction显示文摘 | Li H Ling MX Li CY Zhang H Ding X Yang XY Fan WM Li YL and Sun WD | 2012 | Lithos2012，105，： | 1 |
| 11 | F-18 FDG PET in detecting uterine leiomyoma显示文摘 | Lin CY Ding HJ Chen YK | 2008 | Clin Imaging2008，32，1： | 1 |
| 12 | Chinesemidwives experience of providing continuity of care tolabouring women显示文摘 | Gu CY Zhang Z Ding Y | 2011 | Midwifery2011，27，2： | 1 |
| 13 | Analysis of microRNA-target interactions by a target structure based hybridization model显示文摘 | Long D Chan CY Ding Y | 2008 | Pac Syrup Biocomput2008，，： | 1 |
| 14 | Valproic acid substantiallydownregulated genes folrl,IGF2R,RGS2,COL6A3,EDNRB,KLF6,and pax-3,N-acetylcysteine alleviated most of the inducedgene alterations in chicken embryo model显示文摘 | Hsieh CL Chen KC Ding CY | 2013 | Rom J Morphol Embry-ol2013，54，4： | 1 |
| 15 | Chinese midwives'experience of providing continuity of care to labouring women显示文摘 | Gu CY Zhang Z Ding Y | 2011 | Midwifery2011，27，2： | 1 |
| 16 | Laparoscopic management of spontaneous bilateral tubal pregnancies显示文摘 | Liao CY Ding DC | | 0，，03： | 1 |
| 17 | Gynecological surgery caused vesi- covaginal fistula managed by Latzko operation 显示文摘 | Liao CY Tasi RS Ding DC | 2012 | Taiwan J Ob- stet Gynecol2012，51，： | 1 |
| 18 | Chinese midwives'experience of providing continuity of care to labouring women显示文摘 | Gu CY Zhang Z Ding Y | 2011 | Midwifey2011，27，2： | 1 |
| 19 | Discovery of O-Alkylamino- Tethered Niclosamide Derivatives as Potent and Orally Bioavail- able Anticancer Agents显示文摘 | Chen H J Yang ZD Ding CY | 2013 | Acs Med Chem Lett2013，4，2： | 1 |
| 20 | Upper mantle anisotropy heneath the North cmna from sneu,-wa*: splitting measurements显示文摘 | Chang LJ Wang CY Ding ZF | 2012 | Tectonophysics2012，，23： | 1 |
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