| 7 | Multi-organ failure with atypical liver granulomas following intravesical Bacillus Calmette-Guerin instillation显示文摘Bacillus Calmette-Guerin(BCG) intravesical instillation has been adopted in the treatment of patients with superficial bladder cancer.BCG-induced disseminated infection,though rare,has been associated with the histological finding of epithelioid granulomas in different organs,including the liver.We report the case of an adult patient with multi-organ failure,who developed sepsis,acute respiratory failure and acute hepatic failure with encephalopathy whose liver biopsy confirmed the presence of atypical,granulomatous-like lesions.Recovery was observed only after empirical therapy for Mycobacterium bovis with isoniazid,rifampicin,ethambutol and steroids was introduced.This case highlights the importance of a thorough patient assessment in order to exclude other more common causes of hepatic granulomas and to confirm diagnosis.Histological findings may be non-specific when the liver is involved in BCGinduced disseminated infection. | Michail Kaklamanos Georgia Hardavella Rodoula Trigidou Georgios Dionellis Nikolaos Paissios Nikolaos Koulouris Constantin Goritsas | 2011 | World Journal of Hepatology2011，3，3： | 0 |
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