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| 1 | Plasma Membrane-Associated SCAR Complex Subunits Promote Cortical F-Actin Accumulation and Normal Growth Characteristics in Arabidopsis Roots显示文摘ARP2/3 建筑群, F 肌动朊聚合的高度保存的 nucleator,和它的使活跃之物, SCAR 建筑群,被显示了在叶起重要作用在 Arabidopsis 的表皮的房间形态发生。然而,疤和 ARP2/3 的细胞内部的地点和功能在植物房间的复杂依赖者的肌动朊聚合仍然保持不清楚。我们证明通常认为的疤建筑群子单元 BRK1 和 SCAR1 在扩展叶子和根的细胞对在细胞生长和墙免职的地点的血浆膜局部性。BRK1 本地化是疤依赖者,提供在在 vivo 的这些蛋白质之间的一个协会的进一步的证据。与疤建筑群子单元的血浆膜本地化一致,在根尖端房间的外皮的 F 肌动朊累积在 brk1 异种被减少。而且,破坏 SCAR 或 ARP2/3 建筑群的变化减少渗透半固体媒介的根和他们的能力的生长率,建议减少的刚硬。变异的根的房间墙在 BRK1 和 SCAR1 在邻近的血浆膜被充实的细胞间的连接展出反常结构和作文。一起拿,我们的结果建议复杂依赖者的肌动朊聚合支持的那个疤和 ARP2/3 在为正常生长和墙汇编是重要的血浆膜处理。 | Julia Dyachok Mon-Ray Shao Kevin Vaughn Andrew Bowling Michelle Facette Stevan Djakovic Lauren Clark Laurie Smith | 2008 | Molecular Plant2008,1,6: | 3 |
| 2 | Esophagogastric anastomosis in rats: Improved healing by BPC 157 and L-arginine, aggravated by L-NAME显示文摘AIM To cure typically life-threatening esophagogastric anastomosis in rats, lacking anastomosis healing and sphincter function rescue, in particular. METHODS Because we assume esophagogastric fistulas represent a particular NO-system disability, we attempt to identify the benefits of anti-ulcer stable gastric pentadecapeptide BPC 157, which was in trials for ulcerative colitis and currently for multiple sclerosis, in rats with esophagocutaneous fistulas. Previously, BPC 157 therapies have promoted the healing of intestinal anastomosis and fistulas, and esophagitis and gastric lesions, along with rescued sphincter function. Additionally, BPC 157 particularly interacts with the NOsystem. In the 4 d after esophagogastric anastomosis creation, rats received medication(/kg intraperitoneallyonce daily: BPC 157(10 μg, 10 ng), L-NAME(5 mg), or L-arginine(100 mg) alone and/or combined or BPC 157(10 μg, 10 ng) in drinking water). For rats underwent esophagogastric anastomosis, daily assessment included progressive stomach damage(sum of the longest diameters, mm), esophagitis(scored 0-5), weak anastomosis(m L H2 O before leak), low pressure in esophagus at anastomosis and in the pyloric sphincter(cm H2O), progressive weight loss(g) and mortality. Immediate effect assessed blood vessels disappearance(scored 0-5) at the stomach surface immediately after anastomosis creation. RESULTS BPC 157(all regimens) fully counteracted the perilous disease course from the very beginning(i.e., with the BPC 157 bath, blood vessels remained present at the gastric surface after anastomosis creation) and eliminated mortality. Additionally, BPC 157 treatment in combination with L-NAME nullified any effect of L-NAME that otherwise intensified the regular course. Consistently, with worsening(with L-NAME administration) and amelioration(with L-arginine), either L-arginine amelioration prevails(attenuated esophageal and gastric lesions) or they counteract each other(L-NAME + L-arginine); with the addition of BPC 157(L-NAME + L-arginine + BPC 157), there was a marked beneficial effect. BPC 157 treatment for esophagogastric anastomosis, along with NOS-blocker L-NAME and/or NOS substrate L-arginine, demonstrated an innate NO-system disability(as observed with L-arginine effectiveness). BPC 157 distinctively affected corresponding events: worsening(obtained with L-NAME administration that was counteracted); or amelioration(L-arginine + BPC 157-rats correspond to BPC 157-rats).CONCLUSION Innate NO-system disability for esophagogastric anastomoses, including L-NAME-worsening, suggests that these effects could be corrected by L-arginine and almost completely eliminated by BPC 157 therapy. | Zeljko Djakovic Ivka Djakovic Vedran Cesarec Goran Madzarac Tomislav Becejac Goran Zukanovic Domagoj Drmic Lovorka Batelja Anita Zenko Sever Danijela Kolenc Alen Pajtak Nikica Knez Mladen Japjec Kresimir Luetic Dinko Stancic-Rokotov Sven Seiwerth Predrag Sikiric | 2016 | World Journal of Gastroenterology2016,22,41: | 3 |
| 3 | Rheological behaviour of thixotropic starch显示文摘 | DJAKOVIC L J SOVILJI V MILOSEVIC S | 1990 | Starch/Starke1990,42,: | 1 |
| 4 | Rheological behaviour of thixotropic starch显示文摘 | DJAKOVIC L I SOVIIAI V MILOSEVIC S | 1990 | Starch/St~rke1990,42,: | 1 |
| 5 | Generalization of a theorem of Bohr for bases in spaces of holomorphic functions of several complex variables显示文摘 | AIZENBERG L AYTUNA A DJAKOV P | 2001 | J Math Anal Apple2001,258,2: | 1 |
| 6 | Use of water jet resection in organ-sparing kidney surgery显示文摘 | Basting R F Djakovic N Widmann | 2000 | J Endourol2000,14,6: | 1 |
| 7 | BRICK1/ HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis显示文摘 | Djakovic S Dyachok J Burke M | 2006 | Development2006,133,6: | 1 |
| 8 | Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II显示文摘 | Djakovic SN Schwarz LA Barylko B | | 0,,: | 1 |
| 9 | Juvenile spondyloar2 thropathies associated with Mycoplasma pneumoniae infection 显示文摘 | Harjacek M Ostojic J Djakovic R | 2006 | Clin Rheuma2006,25,4: | 1 |
| 10 | The synthesis and characterization of poly(itaconic) acid显示文摘 | Velickovic J Filipovi J Petrovi -Djakov D | 1994 | Polym Bull1994,32,: | 1 |
| 11 | Juvenile spondyloarthropathies associated with Mycoplasma pneumoniae infection显示文摘 | Harjacek M Ostojic J Djakovic Rode O | 2006 | Clin Rheumatol2006,25,4: | 1 |
| 12 | Juvenile spondyloarthropathies associated with Mycoplasma pneumoniae infection显示文摘 | Harjacek M Ostojic J Djakovic Rode O | 2006 | Clin Rheumato12006,25,4: | 1 |
| 13 | Severe fetal growth retardation in a patient with uterus bicomis, velamentous insertion and partial placental abruption in the 26th week of gestion - a case report 显示文摘 | DJAKOVIC A RIEGER WIRBELAUER J | 2007 | Z Geburtshilfe Neonatol2007,211,4: | 1 |
| 14 | Juvenile spondy loarthropathiesassociated with Mycoplasma Pneumoniae infection显示文摘 | Harjack M Ostojic J Djakovic R | 2006 | Clin Pheumatol2006,25,4: | 1 |
| 15 | Body stalk mlomaly-a case report on a rare congentital defect显示文摘 | Djakovic A Blissing S Vorker HU | 2006 | Zentralbl Gynacel2006,128,6: | 1 |
| 16 | BRICK1/ HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis 显示文摘 | Djakovic S Dyachok J Burke M | 2006 | Development2006,133,6: | 1 |
| 17 | Juvenile spondyloarthropathies associated with mycoplasma pneumoniae infection 显示文摘 | Harjacek M Ostojic J Djakovic Rode O | 2006 | Clin Rheumatol2006,25,4: | 1 |
| 18 | BRICK1/HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis 显示文摘 | Djakovic S Dyachok J Burke M | 2006 | Development2006,133,6: | 1 |
| 19 | Hypospadias显示文摘 | Djakovic N Nyarangi-Dix J Ozturk A | | 0,,01: | 1 |
| 20 | Juvemle spondyloarthropathies associated with Mycoplasma pneumoniae infection显示文摘 | Harjack M Ostojic J Djakovic R | 2006 | clin Rheumatol2006,25,4: | 1 |