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您的检索式：作者名="Dongchao Ma"
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| 1 | Improvement of cardiac function by hepatocyte growth factor via intracoronary transfection in the swine myocardial infarction model显示文摘Objective:To study the amelioration effect of Adenovirus5-mediated human hepatocyte growth factor(Ad5-HGF)on postinfarction heart failure in the swine myocardial infarction model.Methods:Twelve SuZhong young swine were randomly divided into 2 groups with 6 swine in each group:Ad5-HGF-treated group and null-Ad5 group.Four weeks after ligation at left anterior descending coronary artery in swine hearts,Ad5-HGF was transferred to the swine myocardium.Simultaneously,Gated myocardial perfusion imaging was performed to evaluate cardiac perfusion and heart function.After three weeks,Gated myocardial perfusion imaging was performed again,then the hearts were harvested and sectioned to examine the expression of HGF through ELISA.Results:High expression of human HGF was observed in the myocardium of Ad5-HGF-treated group.From 4 weeks to 7 weeks after operation,Left ventricular ejection fraction was increased in Ad5-HGF-treated group.The improvement in LVEF was greater in Ad5-HGF-treated group than that in null-Ad5 group at 7 weeks after operation.Cardiac perfusion was significantly improved in the Ad5-HGF-treated group.Conclusion:High expression of human HGF was observed in the myocardium through intracoronary transfection,which suggests that HGF can ameliorate heart function in swine with postinfarction heart failure. | Wei Wang Zhijian Yang Dongchao Ma Shunlin Xu Yourong Zhang Yuqing Zhang Liansheng Wang Bo Chen Kejiang Cao Wenzhu Ma | 2006 | Journal of Nanjing Medical University2006，20，4： | 2 |
| 2 | Comparative study of effects of bone marrow cell vs. Ad_5-HGF administration via non-infarct-related artery injection in myocardial infarction in swine显示文摘Objective: To evaluate the effect of transplanting bone marrow-derived mesenchymal stem cells(BM-MSCs) or adenovirus5-hepatocyte growth factor(Ad5-HGF) via non-infarct-related artery injection in swine myocardial infarction models. Methods:BM-MSCs were obtained from swine bone marrow and expanded in vitro to a purity of >50%. A myocardial infarction(MI) was created by ligating the distal left anterior descending artery in swine. Either BM-MSCs(5 × 106/ml) or Ad5-HGF(4 × 109 pfu) were transfused via the right coronary artery(non-infarcted artery) four weeks after MI. Gate-controled cardiac perfusion imaging was performed at the end of four and seven weeks after LAD ligation, to evaluate heart function and cardiac perfusion. Morphologic and histologic characteristics of the hearts were also studied. Results:(1)The gate-controlled cardiac perfusion imaging showed that the improvement in LVEF was greater in both treatment groups than in control group at the 4th weeks. (2)In both treatment groups, capillary density was significantly higher than that of control group(P < 0.05). Conclusion:BM-MSCs or Ad5-HGF transplantation via non-infarcted artery administration can stimulate angiogenesis and improve heart function, but there was no difference in therapeutic efficacy between BM-MSCs and Ad5-HGF. | Liansheng Wang Zhijian Yang Wei Wang Dongchao Ma Shunlin Xu Yuqing Zhang Fang Zhou Bo Chen Kejiang Cao Jun Huang | 2007 | Journal of Nanjing Medical University2007，21，2： | 1 |
| 3 | Experimental study of bone marrow-derived mesenchymal stem cells combined with hepatoeyte growth factor transplantation via noninfarct-relative artery in acute myocardial infarction显示文摘 | YANG Zhijian MA Dongchao WANG Wei | 2006 | Gene Ther2006，13，22： | 1 |
| 4 | A LoRaWAN Access Technology Based on Channel Adaptive Adjustment显示文摘Low-power wide area network(LPWAN)has developed rapidly in recent years and is widely used in various Internet of Things(IoT)services.In order to reduce cost and power consumption,wide coverage,LPWAN tends to use simple channel access control protocols,such as the Aloha protocol.This protocol is simple with poor extension capability.In high-density environment,Aloha protocol will lead to low channel utilization,prolonged access and high conflict probability.Therefore,in order to solve the above problems,we propose an enhanced channel access control mechanism based on the existing LoRaWAN protocol,that is,a dynamic listening backoff mechanism.We combine the improved“listen first and then talk”(LBT)mechanism with the current state of the channel to adaptively adjust the size of the backoff window.The theoretical analysis and simulation results show that the proposed mechanism have a better performance than the existing mechanism,it can reduce conflicts in dense environments.By comparison,the packet transmission success rate is increased by 17%. | Li Ma Meng Zhao Dongchao Ma Yingxun Fu | 2020 | Journal of New Media2020，2，1： | 0 |
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