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您的检索式：作者名="Dongfa Sun"
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| 1 | Development of gene-specific markers for acid soil/aluminium tolerance in barley ( Hordeum vulgare L.)显示文摘 | Miao Bian Irene Waters Sue Broughton Xiao-Qi Zhang Meixue Zhou Reg Lance Dongfa Sun Chengdao Li | 2013 | Molecular Breeding2013，，1： | 1 |
| 2 | Molecular approaches unravel the mechanism of acid soil tolerance in plants显示文摘Acid soil is a worldwide problem to plant production. Acid toxicity is mainly caused by a lack of essential nutrients in the soil and excessive toxic metals in the plant root zone. Of the toxic metals, aluminum(Al) is the most prevalent and most toxic. Plant species have evolved to variable levels of tolerance to aluminum enabling breeding of high Al-tolerant cultivars.Physiological and molecular approaches have revealed some mechanisms of Al toxicity in higher plants. Mechanisms of plant tolerance to Al stress include: 1) exclusion of Al from the root tips, and 2) absorbance, but tolerance of Al in root cells. Organic acid exudation to chelate Al is a feature shared by many higher plants. The future challenge for Al tolerance studies is the identification of novel tolerance mechanisms and the combination of different mechanisms to achieve higher tolerance. Molecular approaches have led to significant progress in explaining mechanisms and detection of genes responsible for Al tolerance.Gene-specific molecular markers offer better options for marker-assisted selection in breeding programs than linked marker strategies. This paper mainly focuses on recent progress in the use of molecular approaches in Al tolerance research. | Miao Bian Meixue Zhou Dongfa Sun Chengdao Li | 2013 | The Crop Journal2013，1，2： | 1 |
| 3 | Recombination and mutation shape variations in the major histocompatibility complex显示文摘The major histocompatibility complex(MHC)is closely associated with numerous diseases,but its high degree of polymorphism complicates the discovery of disease-associated variants.In principle,recombination and de novo mutations are two critical factors responsible for MHC polymorphisms.However,direct evidence for this hypothesis is lacking.Here,we report the generation of fine-scale MHC recombination and de novo mutation maps of~5 Mb by deep sequencing(>100×)of the MHC genome for 17 MHC recombination and 30 non-recombination Han Chinese families(a total of 190 individuals).Recombination hotspots and Han-specific breakpoints are located in close proximity at haplotype block boundaries.The average MHC de novo mutation rate is higher than the genome-wide de novo mutation rate,particularly in MHC recombinant individuals.Notably,mutation and recombination generated polymorphisms are located within and outside linkage disequilibrium regions of the MHC,respectively,and evolution of the MHC locus was mainly controlled by positive selection.These findings provide insights on the evolutionary causes of the MHC diversity and may facilitate the identification of disease-associated genetic variants. | Yuying Sun Fang Yuan Ling Wang Dongfa Dai Zhijian Zhang Fei Liang Nan Liu Juan Long Xiao Zhao Yongzhi xi | 2022 | Journal of Genetics and Genomics2022，49，12： | 0 |
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