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| 1 | 稳定化的零价Fe,FeS,Fe3O4纳米颗粒在土壤中的固砷作用机理显示文摘砷是一种广泛存在于土壤和地下水中的污染物.虽然多种铁基材料已被用于受污染土壤中砷的固定,但是关于稳定化的铁系纳米颗粒在该方面的研究鲜见报道.本文研究了3种经淀粉固定的铁系纳米颗粒(零价Fe,FeS,Fe3O4)对两种典型砷污染土壤(果园土壤、靶场土壤)的固砷作用.为了检测纳米颗粒对砷的去除效果,实验中采取了不同的Fe/As摩尔比(5:1~100:1)和接触时间(3或7d).土壤中砷的生物活性和浸出率分别用生理原理提取法(physiologically based extraction test,PBET)和毒性浸出程序(toxicity characteristic leaching procedure,TCLP)方法表征.在实验时间为3d、Fe/As摩尔比为100:1的实验中,果园砂质土壤中砷的生物活性从最初的71.3%±3.1%分别降至30.9%±3.2%(零价Fe)、37.6%±1.2%(FeS)和29.8%±3.1%(Fe3O4);靶场土壤中砷的浸出率从初始0.51%±0.11%分别降至0.24%±0.03%(零价Fe)、0.27%±0.04%(FeS)和0.17%±0.04%(Fe3O4).3种纳米颗粒中Fe3O4的固砷效率最高.比较两种土壤,可以看出该处理方法更适用于铁含量较低、砷初始浸出率较高的果园土壤.结果表明,对于砷污染的贫铁土壤、沉积物和固废等,环境友好的铁系纳米颗粒是十分有效的固砷材料. | 张美一 Wang Yu Zhao Dongye 潘纲 | 2009 | 科学通报2009，54，23： | 23 |
| 2 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 3 | Power-balancing Instantaneous Optimization Energy Management for a Novel Series-parallel Hybrid Electric Bus显示文摘Energy management(EM) is a core technique of hybrid electric bus(HEB) in order to advance fuel economy performance optimization and is unique for the corresponding configuration. There are existing algorithms of control strategy seldom take battery power management into account with international combustion engine power management. In this paper, a type of power-balancing instantaneous optimization(PBIO) energy management control strategy is proposed for a novel series-parallel hybrid electric bus. According to the characteristic of the novel series-parallel architecture, the switching boundary condition between series and parallel mode as well as the control rules of the power-balancing strategy are developed. The equivalent fuel model of battery is implemented and combined with the fuel of engine to constitute the objective function which is to minimize the fuel consumption at each sampled time and to coordinate the power distribution in real-time between the engine and battery. To validate the proposed strategy effective and reasonable, a forward model is built based on Matlab/Simulink for the simulation and the dSPACE autobox is applied to act as a controller for hardware in-the-loop integrated with bench test. Both the results of simulation and hardware-in-the-loop demonstrate that the proposed strategy not only enable to sustain the battery SOC within its operational range and keep the engine operation point locating the peak efficiency region, but also the fuel economy of series-parallel hybrid electric bus(SPHEB) dramatically advanced up to 30.73% via comparing with the prototype bus and a similar improvement for PBIO strategy relative to rule-based strategy, the reduction of fuel consumption is up to 12.38%. The proposed research ensures the algorithm of PBIO is real-time applicability, improves the efficiency of SPHEB system, as well as suite to complicated configuration perfectly. | SUN Dongye LIN Xinyou QIN Datong DENG Tao | 2012 | Chinese Journal of Mechanical Engineering2012，25，6： | 18 |
| 4 | Immobilization of arsenic in soils by stabilized nanoscale zero-valent iron, iron sulfide (FeS), and magnetite (Fe_3O_4) particles显示文摘Arsenic is a widespread contaminant in soils and groundwater. While various iron-based materials have been studied for immobilizing arsenic in contaminated soils, the feasibility of stabilized iron-based nanoparticles has not been reported. This study investigates the effectiveness of using three types of starch-stabilized iron-based nanoparticles, including zero-valent iron (ZVI), iron sulfide (FeS), and magnetite (Fe3O4), for immobilization of arsenic in two representative As-contaminated soils (an orchard soil and a fire range soil). To test the effect of the nanoparticles on the arsenic leachability, As-contaminated soils were amended with the nanoparticles at various Fe/As molar ratios (5:1―100:1) and contact time (3 and 7 d). After three days' treatments of a field-contaminated sandy soil, the PBET-based bioaccessibility of As decreased from an initial (71.3±3.1)% (mean±SD) to (30.9±3.2)% with ZVI, (37.6±1.2)% with FeS, and (29.8± 3.1)% with Fe3O4 at an Fe/As molar ratio of 100:1. The TCLP-based leachability of arsenic in a spiked fire range soil decreased from an initial (0.51±0.11)% to (0.24±0.03)%, (0.27±0.04)% and (0.17±0.04)% by ZVI, FeS, and Fe3O4 nanoparticles, respectively. The Fe3O4 nanoparticles appeared to be more effective (5% or more) than other nanoparticles for immobilizing arsenic. When the two soils were compared, the treatment is more effective on the orchard soil that has a lower iron content and higher initial leachability than on the range soil that already has a high iron content. These results suggest that these innocuous iron-based nanoparticles may serve as effective media for immobilization of As in iron-deficient soils, sediments or solid wastes. | ZHANG MeiYi WANG Yu ZHAO DongYe PAN Gang | 2010 | Chinese Science Bulletin2010，55，4： | 16 |
| 5 | Structural basis of AMPK regulation by adenine nucleotides and glycogen显示文摘激活安培的蛋白质 kinase (AMPK ) 为糖尿病,肥胖,和癌症的治疗是一个中央细胞的精力传感器和精力动态平衡,和一个有希望的药目标的管理者。这里我们人的 α 的现在的低分辨率的水晶结构; 1 β 2 γ 1 holo-AMPK 建筑群跳了到它的 allosteric 调节的人安培和肝糖模仿 cyclodextrin,两个在 phosphorylated (4.05 Å) 并且 non-phosphorylated (4.60 Å) 状态。另外,我们解决了 2.95 Å人的 kinase 领域(KD ) 的结构跳了到邻近的 autoinhibitory 领域(帮助) 并且表现了广泛生物化学并且 mutational 研究。一起,这些研究由安培和肝糖说明 allosteric AMPK 调整的内在的机制,其绑定改变在交替的帮助(安培) 和糖类绑定模块(肝糖) 之间的 equilibria 相互作用。 | Xiaodan Li Lili Wang X Edward Zhou Jiyuan Ke Parker W de Waal Xin Gu M H Eileen Tan Dongye Wang Donghai Wu H Eric Xu Karsten Melcher | 2015 | Cell Research2015，25，1： | 8 |
| 6 | Reductive immobilization of perrhenate in soil and groundwater using starch-stabilized ZVI nanoparticles显示文摘Perrhenate(ReO4-) was used as nonradioactive surrogate for the radionuclide pertechnetate(99TcO-4) to investigate the potential of using starch-stabilized zero valent iron(ZVI) nanoparticles for reductive immobilization of pertechnetate in soil and groundwater.Batch kinetic tests indicated that the starch-stabilized ZVI nanoparticles were able to reductively remove ~96% of perrhenate(10 mg/L) from water within 8 h.XRD analyses confirmed that ReO 2 was the reduction product.A pseudo-first-order kinetic model was able to interpret the kinetic data,which gave a pseudo first order rate constant(kobs) value of 0.43h-1 at pH 6.9 and room temperature(25℃).Increasing solution pH up to 8 progressively increased the reaction rate.However,highly alkaline pH(10) resulted in much inhibited reaction rate.Consequently,the optimal pH range was identified to be from 7 to 8.Increasing solution temperature from 15 to 45℃ increased k obs from 0.38 to 0.53 h-1.The classical Arrhenius equation was able to interpret the temperature effect,which gave a low activation energy value of 7.61 kJ/mol.When the ReO-4-loaded loess was treated with the stabilized nanoparticles suspension([Fe]=560 mg/L),the water leachable ReO-4 was reduced by 57% and nearly all eluted Re was in the form of ReO2.This finding indicates that starch-stabilized ZVI nanoparticles are promising for facilitating in situ immobilization of ReO-4 in soil and groundwater. | LIU HongFang QIAN TianWei ZHAO DongYe | 2013 | Chinese Science Bulletin2013，58，2： | 7 |
| 7 | CONTROL STRATEGY OF A PARALLEL HYBRID CAR WITH A METAL BELT-PLANETARY GEAR CONTINUOUSLY VARIABLE TRANSMISSION SYSTEM显示文摘The most remarkable characteristic of a metal belt-planetary gear continuously variable transmission is a wider ratio range and a bigger torque capacity than a conventional metal pushing belt continuously variable transmission. A parallel hybrid car with this transmission system not only can reduce fuel consumption and pollutant emission at a ECE city cycle, but also can keep the motor working in the most efficiency area and can be started by a lower power motor by oneself. At the same time, the continuously variable transmission system can realize the smooth switch between the motor and the engine. | Sun Dongye Qin Datong Wang HongyanState Key Laboratory of Mechanical Transmission, Chongqing University, Chongqing 400044, China | 2002 | Chinese Journal of Mechanical Engineering2002，15，3： | 5 |
| 8 | Novel mutation in OCRL leading to a severe form of Lowe syndrome显示文摘AIM: To investigate the phenotype and genotype of a family with X-linked recessive Lowe syndrome. METHODS: All the members in the Chinese pedigree underwent comprehensive ophthalmologic and systemic examinations. Genomic DNA was isolated from peripheral blood of the pedigree members and 100 unrelated healthy Chinese subjects. Direct sequencing was performed to screen the exons and intron boundaries of OCRL.RESULTS: The ophthalmological and systemic exami nations suggested that the affected individual had Lowe syndrome. The phenotype in the pedigree is severe and consistent among all the affected individuals except for an individual who additionally suffered from congenital heart disease and laryngeal cartilage dysplasia. Directio nal San ger sequenci ng identified a complex mutation c.(2368_2368delG;c.2370A>C) in the Rho-GTPase activating protein domain. This complex mutation causes termination of protein synthesis at amino acid 824 and result in a new peptide with 823 amino acids (p.Ala790ProfsX34). This mutation was not detected in 100 unrelated healthy Chinese subjects.CONCLUSION: Our findings expand the phenotypic and genotypic spectrum of Lowe syndrome. | Feng-Qi Zhou Qi-Wei Wang Zhen-Zhen Liu Xu-Lin Zhang Dong-Ni Wang Mei-Mei Dongye Hao-Tian Lin Wei-Rong Chen | 2019 | International Journal of Ophthalmology(English edition)2019，12，7： | 5 |
| 9 | Experimental study on electrical conductivity of dunite at high temperature and pressure——The evidence of electrical conductivity of cold mantle in the Gaize-Lugu area显示文摘The electrical conductivities of the dunite from the Qinghai-Xizang (Tibetan) Plateau were measured with the impedance spectra method at 1.0-4.0 GPa and 643-1093 K. The experimental results indicated that activation enthalpies of the dunite are smaller than 0.9 eV, the conduction mechanism in dunite may be attributed to the mixed electrical conduction involving grain interiors and boundaries. On the basis of the results of this experiment, we can deduce that there exists cold mantle in the area of Gaize-Lugu in the Qinghai-Xizang (Tibetan) Plateau by reverse methods from the magnetotelluric sounding data (conductivity-depths profile) available for western Tibet. The result provides the present cold mantle viewpoint with strong proof on the basis of high temperature and pressure experiments. | WANG Duojun LI Heping LIU Congqiang ZHAO Zhidan MO Xuanxue GUO Tieying SU Gengli DING Dongye | 2001 | Chinese Science Bulletin2001，46，24： | 5 |
| 10 | STUDY ON CONTROL STRATEGY OF CLUTCH STARTING FOR CAR WITH A METAL PUSHING BELT-PLANETARY GEAR CONTINUOUSLY VARIABLE TRANSMISSION SYSTEM显示文摘The automatic control of clutch startion in car with a metal pushing belt-planetary gear continuously variable transmission (CVT)is a complex problem.A suited control strategy is required to ralize quick and smooth start.A simulation state space equation is established on clutch startion control of a car startion process to weaken the jerk motion is introduced.The simulation results indicate that the jerk motion of clutch startiong is below 10m/s^3. | Sun Dongye Qin Datong Wang Hongyan State Key Laboratory of Mechanical Transmission, Chongqing University, Chongqing 400044,China | 2002 | Chinese Journal of Mechanical Engineering2002，15，1： | 5 |
| 11 | 全身麻醉剂激活杏仁核内一个强效的中枢镇痛环路显示文摘全身麻醉产生的镇痛作用独立于其引起意识消失的作用,但背后机制却不清楚。本研究假设全身麻醉药通过激活高级中枢产生镇痛。研究者发现小鼠中央杏仁核(CeA)存在一类特殊的由全身麻醉药激活的GABA能神经元集群(称作CeAGA神经元)。在体钙成像实验显示不同的全身麻醉药可激活共同的CeAGA神经元集群。CeAGA神经元有本底放电活动,但主要是反应小鼠身体的内部状态。光遗传兴奋CeAGA神经元显著减少疼痛引发的反射性行为和自愈性(如舔舐、擦拭)行为以及抑制慢性神经病理性疼痛引发的机械痛敏。相反,抑制CeAGA神经元活动会加剧疼痛,带来强烈的厌恶感并抑制低剂量氯胺酮的镇痛效应。此外,CeAGA神经元广泛投射到痛觉相关脑区。本研究表明CeAGA是缓解慢性疼痛的潜在的强效治疗靶标。 | Thuy Hua Bin Chen Dongye Lu 李紫阳(译) 张玲(校) | 2020 | 中国疼痛医学杂志2020，26，11： | 4 |
| 12 | RBC Membrane Camouflaged Semiconducting Polymer Nanoparticles for Near-Infrared Photoacoustic Imaging and Photothermal Therapy显示文摘Semiconducting conjugated polymer nanoparticles(SPNs)represent an emerging class of phototheranostic materi-als with great promise for cancer treatment.In this report,low-bandgap electron donoracceptor(DA)-conjugated SPNs with sur-face cloaked by red blood cell membrane(RBCM)are developed for highly e ective photoacoustic imaging and photothermal therapy.The resulting RBCM-coated SPN(SPN@RBCM)displays remarkable near-infrared light absorption and good photosta-bility,as well as high photothermal conver-sion e ciency for photoacoustic imaging and photothermal therapy.Particularly,due to the small size(<5 nm),SPN@RBCM has the advantages of deep tumor penetration and rapid clearance from the body with no appreciable toxicity.The RBCM endows the SPNs with prolonged systematic circulation time,less reticuloendothelial system uptake and reduced immune-recognition,hence improving tumor accumulation after intravenous injection,which provides strong photoacoustic signals and exerts excellent photothermal therapeutic e ects.Thus,this work provides a valuable paradigm for safe and highly e cient tumor pho-toacoustic imaging and photothermal therapy for further clinical translation. | Dongye Zheng Peiwen Yu Zuwu Wei Cheng Zhong Ming Wu Xiaolong Liu | 2020 | Nano-Micro Letters2020，12，7： | 3 |
| 13 | Effect of puerarin on myocardial perfusion and ventricular wall motion in patients with acute coronary syndrome显示文摘Objective To investigate the effects of puerarin (Pur) on myocardial perfusion and ventricular wall motion in patients with acute coronary syndrome (ACS).Methods Thirty-seven patients with ACS were randomly divided into two groups:conventional treatment group (n= 17,11 males,range of age:32-80 years,average age:60.9±4.9 years) and Pur treatment group (n=20,12 males,range of age:40-76 years,average age:62.7±3.5 years).Patients in the conventional treatment group received standard treatment according to the current guidelines,while patients in the Pur treatment group received intravenous administration of Pur (500 mg/day) for 10 days plus conventional treatment.Real-time myocardial contrast echocardiography (RT-MCE) was performed to evaluate the change in myocardial perfusion index (MPI) and ventricular wall motion index (VWMI) at admission and 10 days after treatment.Results At 10 days after treatment,MPI was significantly higher (P<0.01) and VWMI significantly lower (P<0.01) in the Pur group comparing with those in the conventional group.Conclusions Puerarin might improve myocardial microcirculation perfusion and ventricular wall motion in patients with ACS. | Ling Niu Dongye Li Yong Xia Defeng Pan Xiaoping Wang Yan Yan Li Liang Tongda Xu Cardiovascular Institute of Xuzhou Medical College, Department of Cardiology, Affiliated Hospital, Xuzhou Medical College, Xuzhou, Jiangsu 221002, China | 2008 | Journal of Geriatric Cardiology2008，5，3： | 3 |
| 14 | Integrated Control Strategy for CVT Powertrains with Consideration of Vehicle Drivability显示文摘During shift,power flow is not interrupted in powertrains equipped with continuously variable transmission(CVT).When hard acceleration is commanded,engine speed will flare and corresponding torque will be consumed,which leads to a drop in vehicle drive torque and also the vehicle acceleration.This is the reason why CVT vehicles have poor drivability during hard acceleration maneuver.Conventional method such as torque compensation doesn't always work due to the limited backup torque of engine.According to this,means to evaluate the drivability of CVT vehicles are studied,affect factors of drivability are analyzed in detail.Hard acceleration process of CVT vehicle is studied by theoretical analysis,based on which engine torque and ratio change rate of CVT are identified as two key control parameters that decide the drivability of CVT vehicles during hard acceleration maneuver.Therefore,a control strategy based on restricting the change rate of CVT ratio together with torque compensation is proposed,and two different algorithms to establish the limitation of ratio change rate are proposed.These two algorithms are simulated and compared with each other,results indicate that drop of vehicle acceleration is eliminated evidently by limit the change rate of CVT ratio,but small ratio change rate also results in a longer time to finish the accelerate process,an algorithm to decide a proper ratio change rate is needed in order to tune these different characteristics.In order to get better control effects,a new fuzzy logic based algorithm is proposed to decide a proper ratio change rate during kick down conditions,simulation and experiment results indicate that,the amount of vehicle acceleration decrease is reduced from about 1 m/s2 to almost 0,in the mean time the accelerate process only delayed for about 0.3 s.The proposed control strategy and algorithm can effectively tune the characteristics of CVT equipped vehicle during kick down conditions. | SUN Dongye LUO Yong QIN Datong | 2012 | Chinese Journal of Mechanical Engineering2012，25，3： | 3 |
| 15 | Impedance spectra of hot, dry gabbro at high temperature and pressure显示文摘Impedance spectra of hot, dry gabbro have been studied at 1.0~2.0 Gpa and 593~1173 K.The experimental results indicate that complex impedance depends on frequency of altering current. Impedance arcs representing grain interiors and grain boundaries conduction mechanism are displayed in the complex impedance plane. The impedance arc corresponding to grain interiors occurs over the range of 102~105 Hz, and the impedance arc corresponding to grain boundaries occurs over the range of 12~102 Hz. Each element of equivalent circuit corresponding to grain interiors is fit for complex nonlinear least square program. When garnet occurs in gabbro, the electrical conductivity of gabbro abruptly changes. | WANG Duojun, LIU Congqiang, LI Heping, YI Li, SU Genli and DING Dongye( Laboratory for Study of the Earth’s Interior and Geofluids, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China) | 2002 | Progress in Natural Science:Materials International2002，12，5： | 3 |
| 16 | Reductive immobilization and long-term remobilization of radioactive pertechnetate using bio-macromolecules stabilized zero valent iron nanoparticles显示文摘Reductive immobilization of radioactive pertechnetate(99TcO4^-) in simulated groundwater was studied by prepared carboxymethyl cellulose(CMC) and starch stabilized zero valent iron nanoparticles(nZVI),and long-term remobilization of reduced Tc was also evaluated under anoxic and oxic conditions.The stabilized nZVI can effectively reduce soluble 99Tc(Ⅶ) to insoluble 99 Tc(Ⅳ),and they can be easily delivered into a contaminated groundwater zone and facilitate in situ remediation.In this study,CMCstabilized nZVI showed higher reactivity than that using starch as the stabilizer.Batch experiments indicated that more than 99% of 99 Tc(Ⅶ)(CO=12 mg/mL) was reduced and removed from groundwater by CMC-stabilized nZVI with a CMC content of 0.2%(w/w) at a broad pH of 5-8.X-ray diffraction(XRD)and X-ray photoelectron spectroscopy(XPS) analyses further confirmed that 99Tc(Ⅶ)O4^-transformed into 99Tc(Ⅳ)O2(s).The presence of bicarbonate exhibited insignificant effect on Tc immobilization,while humic acid(HA) inhibited reaction mainly due to retardation on electron transfer and formation of Tc(IV)-HA complexes.More interesting,the immobilized Tc(Ⅳ) remained insoluble even after 120 d under anoxic condition,while only^21 % was remobilized when exposed to air.Therefore,biomacromolecules stabilized nZVI nanoparticles could be a viable alternative for in situ remediation of radioactive contamination in groundwater. | Haodong Ji Yangmo Zhu Jun Duan Wen Liu Dongye Zhao | 2019 | Chinese Chemical Letters2019，30，12： | 3 |
| 17 | In vitro inhibiton of proliferation of HL-60 cells by tetrandrine and coriolus versicolor peptide derived from Chinese medicinal herbs显示文摘 | DONGY YANGM M KWANC Y | 1997 | Life Sci1997，60，8： | 1 |
| 18 | Destruction of lindane and atrazine using stabilized iron nauoparticles under aerobic and anaerobic conditions: effects of catalyst and stabilize 显示文摘 | Joo S H Zhao Dongye | 2008 | Chemosphere2008，70，3： | 1 |
| 19 | 在冻土地区通风管道路堤与烟囱冷却效果的试验调查[J]显示文摘 | ZhangM LaiY DongY LiS | 2008 | 寒区科技2008，54，2： | 1 |
| 20 | The On-Line Rental Problem Under Risk-Re-ward Model With Probabilistic Forecast显示文摘 | DongY Xu J Xu Y | 2011 | Information2011，14，1： | 1 |
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