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| 1 | Role of frailty and sarcopenia in predicting outcomes among patients undergoing gastrointestinal surgery显示文摘According to the United States census bureau 20% of Americans will be older than 65 years in 2030 and half of them will need an operation- equating to about 36 million older surgical patients. Older adults are prone to complications during gastrointestinal cancer treatment and therefore may need to undergo special pretreatment assessments that incorporate frailty and sarcopenia assessments. A focused, structured literature review on Pub Med and Google Scholar was performed to identify primary research articles, review articles, as well as practice guidelines on frailty and sarcopenia among patients undergoing gastrointestinal surgery. The initial search identified 450 articles; after eliminating duplicates, reports that did not include surgical patients, case series, as well as case reports, 42 publications on the impact of frailty and/or sarcopenia on outcome of patients undergoing gastrointestinal surgery were included. Frailty is defined as a clinically recognizable state of increased vulnerability to physiologic stressors resulting from aging. Frailty is associated with a decline in physiologic reserve and function across multiple physiologic systems. Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength. Unlike cachexia, which is typically associated with weight loss due to chemotherapy or a general malignancy-related cachexia syndrome, sarcopenia relates to muscle mass rather than simply weight. As such, while weight reflects nutritional status, sarcopenia- the loss of muscle mass- is a more accurate and quantitative global marker of frailty. While chronologic age is an important element in assessing a patient's peri-operative risk, physiologic age is a more important determinant of outcomes. Geriatric assessment tools are important components of the preoperative work-up and can help identify patients who suffer from frailty. Such data are important, as frailty and sarcopenia have repeatedly been demonstrated among the strongest predictors of both short- and longterm outcome following complicated surgical procedures such as esophageal, gastric, colorectal, and hepatopancreatico-biliary resections. | doris wagner mara mcadams demarco neda amini stefan buttner dorry segev faiz gani timothy m pawlik | 2016 | World Journal of Gastrointestinal Surgery2016，8，1： | 8 |
| 2 | Annexin A2 as a biomarker for hepatocellular carcinoma in Egyptian patients显示文摘AIM To investigate the clinical utility of serum annexin A2(ANXA2) as a diagnostic marker for early hepatocellular carcinoma(HCC).METHODS This study was performed in HCC Clinic of Ain Shams University Hospitals, Cairo, Egypt and included: Group 1: Fifty patients with early stage HCC(Barcelona Clinic Liver Cancer stage A); Group 2: Twenty five patients with chronic liver disease; and Control Group: Fifteen healthy, age-and sex-matched subjects who were seronegative for viral hepatitis markers. The followinglaboratory investigations were done: Viral hepatitis markers [hepatitis B surface antigen and hepatitis C virus(HCV) antibodies], HCV RNA in HCV antibody-positive patients, serum alpha fetoprotein(AFP), and serum ANXA2 levels.RESULTS In this study, 88% of HCC patients(n = 44) were HCVpositive, while HBV infection represented only 8% of all HCC patients(n = 4); and two patients were negative for both viral markers. A highly significant difference was found between patients with HCC and chronic liver disease as well as controls with regard to serum ANXA2 levels(130, IQR 15-240; 15, IQR 15-17; and 17, IQR 15-30 ng/m L, respectively). The area under the curve of ANXA2 was 0.865; the cut-off value was established to be 18 ng/mL with a diagnostic sensitivity of 74% and a specificity of 88%, while the sensitivity and specificity of AFP at the cut-off value of 200 ng/dL were 20% and 100%, respectively.CONCLUSION Serum ANXA2 may serve as a biomarker for the early detection of HCC. | Mohamed K Shaker Hanzada I Abdel Fattah Ghada S Sabbour Iman F Montasser Sara M Abdelhakam Eman El Hadidy Rehab Yousry Ahmed K El Dorry | 2017 | World Journal of Hepatology2017，9，9： | 4 |
| 3 | Overview of flotation deinking显示文摘 | Dorris G Ben Y Ricard M | 2011 | Progress in paper recycling2011，20，1： | 1 |
| 4 | Scheduling part-time and mixed-skilled workers to maximize employee satisfaction 显示文摘 | AKBARI M ZANDIEH M DORRI B | 2013 | Inter- national Journal of Advonced Manufacturing Technology2013，64，： | 1 |
| 5 | Effect of Initial pH on the Deflaking Rate of Recovered Papers显示文摘 | F Brouillette C Daneault G M Dorris | 2003 | Pulp and Paper Canada2003，104，7： | 1 |
| 6 | Deinking of new water-basedgravure inks 显示文摘 | Hooper C Daneauh C Dorris G M | 1996 | Pulp Paper Can1996，97，8： | 1 |
| 7 | The Surface Analysis of Paper and Wood Bres by ESCA I Application to Cellulose and Lignin显示文摘 | DORRIS G M GRAY D G | 1978 | Cellul Chem Technol1978，12，： | 1 |
| 8 | The Surface Analysis of Paper and Wood Bres by ESCA II Surface Composition of Mechanical Pulps]显示文摘 | DORRIS G M GRAY D G | 1978 | Cellul Chem Technol1978，12，： | 1 |
| 9 | Comparison of microstickies measurement methods, part Ⅱ: results and discussion显示文摘 | Roshi M R Blanco A Dorris G M | 2003 | Progress in Paper Recycling2003，13，1： | 1 |
| 10 | Passive shimming of MR magnets: algorithm, hardware, and results 显示文摘 | DORRI B VERMILYEA M E | 1993 | IEEE Transactions on Applied Super-conductlvlty1993，3，1： | 1 |
| 11 | The surface analysis of paper and wood fiber by ESCA, 2:Surface composition of mechanical pulps显示文摘 | DORRIS G M GRAY D G | 1978 | Cellulose Chem Technol1978，12，3： | 1 |
| 12 | Effect of initial pH on the deflaking rate of recovered papers显示文摘 | Brouillette F Daneault C Dorris G M | 2003 | Pulp and Paper Canada2003，104，7： | 1 |
| 13 | A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil显示文摘 | Tauro A Dorris M L | 1989 | Endocrinology1989，124，： | 1 |
| 14 | Molecular phylogenetic analysis of the genus Strongyloides and related nematodes 显示文摘 | Dorris M Viney M E Blaxter M L | 2002 | International Journal of Parasitology2002，32，： | 1 |
| 15 | Effects of mud washing and calcining temperature on lime properties 显示文摘 | Dorris G M | 2003 | Journal of Pulp and Paper Science2003，29，6： | 1 |
| 16 | Analysis of Metal Soaps in Kraft Mill Brownstock Pitch Deposits显示文摘 | Dorris Gm Douek M Allen L H | 1983 | Pulp & Paper Canada1983，84，3： | 1 |
| 17 | The surface analysis of paper and wood fibers by esca-electron spectroscopy for chemical analysis Ⅰ:applications to cellulose and lignin显示文摘 | DORRIS G M GRAY D G | | 0，，： | 1 |
| 18 | Handsheet and Pulp Pad Preparation for Measurement of Total and Bound Ink in ONP/OMG Furnishes 显示文摘 | Ben Yuxia Dorris Gilles M | 1999 | Progress in Paper Recycling1999，，2： | 1 |
| 19 | Effect of Initial pH on the Release of Dissolved, Colloidal and Suspended Solids During Repulping of ONP and OMG显示文摘 | Brouillette F Da nealut C Dorris G M | 2002 | Journal of Pulp and Paper Science2002，28，2： | 1 |
| 20 | Thermogravimetric dermination of synthetic polymers in recycled pulp systems and deposits显示文摘 | Castro C Dorris G M Brouillette F el al | 2003 | J Pulp Paper Sci2003，29，5： | 1 |
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