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| 1 | A comparison of survival and pathologic features of non-alcoholic steatohepatitis and hepatitis C virus patients with hepatocellular carcinoma显示文摘AIM:To compare the clinical outcome and pathologic features of non-alcoholic steatohepatitis(NASH) patients with hepatocellular carcinoma(HCC) and hepatitic C virus(HCV) patients with HCC(another group in which HCC is commonly seen) undergoing liver transplantation.METHODS:Patients transplanted for HCV and NASH at our institution from January 2000 to April 2011 were analyzed.All explanted liver histology and pre-transplant liver biopsies were examined by two specialist liver histopathologists.Patient demographics,disease free survival,explant liver characteristics and HCC features(tumour number,cumulative tumour size,vascular invasion and differentiation) were compared between HCV and NASH liver transplant recipients.RESULTS:A total of 102 patients with NASH and 283 patients with HCV were transplanted.The incidence of HCC in NASH transplant recipients was 16.7%(17/102).The incidence of HCC in HCV transplant recipients was 22.6%(64/283).Patients with NASH-HCC were statistically older than HCV-HCC patients(P < 0.001).A significantly higher proportion of HCV-HCC patients had vascular invasion(23.4% vs 6.4%,P = 0.002) and poorly differentiated HCC(4.7% vs 0%,P < 0.001) compared to the NASH-HCC group.A trend of poorer recurrence free survival at 5 years was seen in HCV-HCC patients compared to NASH-HCC who underwent a Liver transplantation(P = 0.11).CONCLUSION:Patients transplanted for NASH-HCC appear to have less aggressive tumour features compared to those with HCV-HCC,which likely in part accounts for their improved recurrence free survival. | Roberto Hernandez-Alejandro Kris P Croome Martin Drage Nathalie Sela Jeremy Parfitt Natasha Chandok Paul Marotta Cheryl Dale William Wall Douglas Quan | 2012 | World Journal of Gastroenterology2012,18,31: | 5 |
| 2 | Evaluation of activated carbon adsorbents for CO2capture in gasification显示文摘 | Drage T C Blackman J M Pevida C | 2009 | Energy&Fuels2009,23,5: | 1 |
| 3 | Novel lithium-based sorbents from fly ashes for CO2 capture at high temperatures 显示文摘 | OLIVARES-MARr N M DRAGE T C MAROTO-VALER M M | 2010 | International Journal of Greenhouse Gas Control2010,4,: | 1 |
| 4 | Effective dose from cone beam CT examinations in dentistry显示文摘 | ROBERTS J A DRAGE N A DAVIES J | 2009 | Br J Radiol2009,82,973: | 1 |
| 5 | Extracorporeal shockwave lithotripsy in the management of salivary calculi显示文摘 | Escudier MP Brown JE Drage NA | 2003 | Br J Sur2003,90,: | 1 |
| 6 | Herpes zoster (shingles) and postherpetic neuralgia显示文摘 | Sampathkumar P Drage L A Martin D P | 2009 | M ayo Clin Proc2009,84,: | 1 |
| 7 | Effective dose from cone beam CT examinations in dentistry显示文摘 | JAROBERTS N A DRAGE J DAVIES | 2009 | The British Journal of Radiology2009,3540,: | 1 |
| 8 | A case report of massive vaginal variceal hemorrhage in a patient with cirrhosis secondary to nonalcoholic steatohepatitis unresolved even after successful liver transplantation 显示文摘 | Chart G Taqi A Drage M | 2013 | Transplant Proc2013,45,2: | 1 |
| 9 | CO2 capture using some fly ash - derived carbon materials 显示文摘 | Arenillas A Smith K M Drage T C | 2005 | Fuel2005,84,17: | 1 |
| 10 | Herpes zoster (shingles) and postherpetic neuralgia显示文摘 | Sampathkumar P Drage L A Martin D P | 2009 | Mayo Clin Proc2009,84,3: | 1 |
| 11 | Effective dose from cone beam CT examinations in dentistry显示文摘 | Roberts J A Drage N A Davies J | 2009 | Br J Radiol2009,82,973: | 1 |
| 12 | First Photosubstitution Chemistry of Fulvalene-bridged Metal-metal Bonded Carbonyls: Synthesis and Structural Determination of Novel Homo-and Heterobimetallic Alkyne Complexes 显示文摘 | DRAGE J S TILSET M VOLLHARDT K P C | 1984 | Organometallies1984,3,5: | 1 |
| 13 | Interventional radiology in the removal of salivary calculi显示文摘 | Drage NA Brown JE Escudier MP | 2000 | Radiology2000,214,: | 1 |
| 14 | Herpes zoster ( shingles ) and postherpetic neuralgia 显示文摘 | SAMPATHKUMAR P DRAGE LA MARTIN DP | 2009 | Mayo Clin Proc2009,84,3: | 1 |
| 15 | CO2 capture using some fly ash-derived carbon materials显示文摘 | Arenillas A Smith K M Drage T C | | 0,,17: | 1 |
| 16 | Vertebrate caudal gene expression gradients investigated by use of chick cdx-A /1acⅠ and mouse cdx-1/1acⅠ reporters in transgenic mouse embryos: evidence for an imtron enhancer显示文摘 | Gaunt S J Drage D Cockley A | 2003 | Mech Dev2003,120,5: | 1 |
| 17 | Balloon dilatation of salivary duct strictures: Report on 36 treated glands 显示文摘 | Drage NA Brown JE Escudier MP | 2002 | Cardiovasc Intervent Radiol2002,25,: | 1 |
| 18 | Temporal trends in concentrations of legacy and novel brominated flame retardants in house dust from Birmingham in the United Kingdom显示文摘Concentrations of polybrominated diphenyl ethers(PBDEs),hexabromocyclododecane(HBCDD),tetrabromobisphenol-A(TBBPA)and two potential replacements decabromodiphenylethane(DBDPE)and 1,2-bis(2,4,6-tribromophenoxy)ethane(BTBPE)were measured in dust samples collected from 14 homes across Birmingham(UK).Concentrations were compared with those from the same city in previous studies to ascertain any temporal changes and to assess the effects of legislative restrictions.The average PHBCDDs concentration(46,000 ng/g;median=280 ng/g)included the highest dust concentration recorded globally(570,000 ng/g).This is despite the listing of HBCDD under the Stockholm Convention in 2013,demonstrating that decreases in indoor contamination will likely be slow as existing sources are gradually discarded.In contrast,concentrations of BDE-47(mean=5.7 ng/g;median=0.93 ng/g)and BDE-99(mean=11 ng/g;median=2.9 ng/g)were significantly lower than in all previous(p<0.01)studies in the same city since 2006,suggesting restrictions on the Penta-BDE formulation have been effective.The average BDE-209 concentration(4800 ng/g;median=1600 ng/g)is lower than the peak average concentration,which was observed in 2007(280,000 ng/g),however this is not a significant decline,probably due to the later imposition of Deca-BDE restrictions compared to those on Penta-BDE.Decreases in PBDE concentrations have coincided with a significant(p<0.01)increase in DBDPE concentrations(average=1500 ng/g;median=660 ng/g)since 2014,suggesting its use as a replacement flame retardant for Deca-BDE.While no significant change was detected for BTBPE(average 11 ng/g;median=0.84 ng/g in this study);concentrations of TBBPA(average=34 ng/g;median=35 ng/g)were significantly lower(p<0.05)than in 2007(average 62 ng/g).The decreases observed in PBDE concentrations,demonstrates that legislation has been effective in reducing the commercial use of PBDEs,however this has coincided with increases of alternative flame retardants such as DBDPE. | Daniel Simon Drage Sonthinee Waiyarat Stuart Harrad Mohamed Abou-Elwafa Abdallah Suwanna Kitpati Boontanon | 2020 | Emerging Contaminants2020,6,1: | 1 |
| 19 | Developing activated carbon adsorbents for pre-combustion CO2 capture显示文摘 | Drage T C Kozynchenko O Pevida C | | 0,,01: | 1 |
| 20 | On-Line Monitoring of Micropollutants in the River Trent(UK)with Respect to Drinking Water Abstraction显示文摘 | D E Drage J E Upton M Purvis | 1998 | Wat Sci Tech1998,38,11: | 1 |