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| 1 | Distribution of Plutonium and Americium Beneath a 33-yr-old Liquid Waste Disposal Site显示文摘 | Nyhan J W Drennon B J Abeele W V | 1985 | J Environ Qual1985，14，： | 1 |
| 2 | A water balance study of two landfill cover designs for semiarid regions显示文摘 | Nyhan J W Hakonson T E Drennon B J | 1990 | Journal of Environmental Quality1990，19，3： | 1 |
| 3 | Development of an enzyme-linked immunosorbent assay for the measurement of plasma growth hormone (GH) levels in channel catfish (Ictalurus punctatus): assessment of environmental salinity and GH secretogogues on plasma GH levels 显示文摘 | DRENNON K MORIYAMA S KAWAUCHI H | 2003 | General and Comparative Endocrinology2003，133，3： | 1 |
| 4 | The effect of tray se- lection on the accuracy of elastomeric impression materials 显示文摘 | Gordon GE Johnson GH Drennon DG | 1990 | J Prosthet Dent1990，63，1： | 1 |
| 5 | The accuracy and efficacy of disinfection by spray atomization on elastomeric impressions显示文摘 | Drennon DG Johnson GH Powell GL | 1989 | Int J Prosthodont1989，62，4： | 1 |
| 6 | The accuracy and efficacy of disinfection by spray atomization on elastomeric impressions显示文摘 | Johnson GH Powell GL | 1989 | J Prosthet Dent1989，62，： | 1 |
| 7 | A water balance study of two landfill cover designs for semiarid regions 显示文摘 | Nyhan J W Hakonson T E Drennon B J | 1990 | J Environ Quality1990，19，3： | 1 |
| 8 | Case : A com- puter-aided simulation of the clinical encounter 显示文摘 | Harless WG Drennon GG Marxer JJ | 1971 | J Med Edu1971，46，： | 1 |
| 9 | The effect of tray selection on the accuracy of elastomeric impression materials显示文摘 | Gordon GE Johnson GH Drennon DG | 1990 | J Prosthet Dent1990，63，1： | 1 |
| 10 | A water balance study of two landfill cover designs for semiarid regions 显示文摘 | Nyhan J W Hakonson T E Drennon B J | 1990 | Journal of Environmental Quality1990，19，3： | 1 |
| 11 | Accuracy of elastomeric impressions disinfected by immersion显示文摘 | Johnson GH Drennon DG Powel GL | | 0，，04： | 1 |
| 12 | Case: a computer-aided simulation of the clinical encounter显示文摘 | Harless WG Drennon GG Marxer J J | 1971 | J Med Educ1971，46，5： | 1 |
| 13 | Awater balance study of two landfill cover designs for semiarid regions显示文摘 | Nyhan J W Hakonson T E Drennon B J | 1990 | Journal of Environmental Quality1990，19，3： | 1 |
| 14 | A water balance study of two landfill cover designs for semiard regions显示文摘 | Nyhan J W Hakonson T E Drennon B J | 1990 | J Environ Quality1990，19，3： | 1 |
| 15 | A water balance study of two landfill cover designs for semiarid regions 显示文摘 | Nyhan J W Hakonson T E Drennon B J | 1990 | Journal of Environmental Quality1990，19，3： | 1 |
| 16 | Spatial transcriptomic interrogation of the murine bone marrow signaling landscape显示文摘Self-renewal and differentiation of skeletal stem and progenitor cells(SSPCs)are tightly regulated processes,with SSPC dysregulation leading to progressive bone disease.While the application of single-cell RNA sequencing(scRNAseq)to the bone field has led to major advancements in our understanding of SSPC heterogeneity,stem cells are tightly regulated by their neighboring cells which comprise the bone marrow niche.However,unbiased interrogation of these cells at the transcriptional level within their native niche environment has been challenging.Here,we combined spatial transcriptomics and scRNAseq using a predictive modeling pipeline derived from multiple deconvolution packages in adult mouse femurs to provide an endogenous,in vivo context of SSPCs within the niche.This combined approach localized SSPC subtypes to specific regions of the bone and identified cellular components and signaling networks utilized within the niche.Furthermore,the use of spatial transcriptomics allowed us to identify spatially restricted activation of metabolic and major morphogenetic signaling gradients derived from the vasculature and bone surfaces that establish microdomains within the marrow cavity.Overall,we demonstrate,for the first time,the feasibility of applying spatial transcriptomics to fully mineralized tissue and present a combined spatial and single-cell transcriptomic approach to define the cellular components of the stem cell niche,identify cell-cell communication,and ultimately gain a comprehensive understanding of local and global SSPC regulatory networks within calcified tissue. | Xue Xiao Conan Juan Tingsheng Drennon Cedric R.Uytingco Neda Vishlaghi Dimitri Sokolowskei Lin Xu Benjamin Levi Mimi C.Sammarco Robert J.Tower | 2023 | Bone Research2023，11，4： | 0 |
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