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| 1 | Expression of IL-10 and TNF-α in Rats with Cerebral Infarction after Transplantation with Mesenchymal Stem Cells显示文摘我们调查了骨头的效果在老鼠的 MCAO (中间的服的动脉吸藏) 的神经病学的功能的恢复上的导出髓的间充质的干细胞(MSC ) 移植模型和它的 mechanism.MSCs 从男 Sprague Dawley (SD ) 老鼠的骨头髓被孤立。女成年 SD 老鼠随机被分配进 4 个组:假冒操作组, MCAO 组,车辆组和 MCAO +对待 MSCs 的组。MSC 在对待 MSCs 的组被注入老鼠的侧面的室, PBS 的一样的体积被给车辆组。IL-10 和 TNF- 的表情在 MCAO 以后是由在白天 1 和 4 点的 RT-PCR 和 ELISA 察觉的 assayed。梗塞体积被染色 TTC 测量。老鼠经历了的所有行为的测试在前,以及在 MCAO 以后的 1, 4,和 14 天。MSC 显著地在在移植以后的白天 14 点与控制相比改进了功能的恢复。与 MCAO 组和车辆相比,组, IL-10 mRNA 的表示和它的蛋白质显著地在 MSC 组铺平 upregulated。然而, TNF 的表示 -- 4 显著地在在 MSC 的 MCAO 以后组织的一 at 天与 MCAO 组和车辆组的相比减少了。作为结果,有 MSC 的移植显著地减少了在白天 1 和 4 点的梗塞体积。这研究强烈建议有 MSC 的移植能减少 neuronal 损害由在大脑调整 IL-10 和 TNF- 的表达式部分在老鼠张贴焦点的服的局部缺血。细胞与分子的免疫学。2009; 6 (3 ): 207-213。 | Nan Liu Ronghua Chen Houwei Du Jiehua Wang Yixian Zhang Jinsen Wen | 2009 | Cellular & Molecular Immunology2009，6，3： | 40 |
| 2 | CONTINUUM TOPOLOGY OPTIMIZATION FOR MONOLITHIC COMPLIANT MECHANISMS OF MICRO-ACTUATORS显示文摘为分布式的顺从的机制的结构的拓扑学优化的一个多客观的计划处于 MEMS 状况微致动器在这个工作,机械灵活性和结构的僵硬在是看作客观功能的两个被介绍。这样开发的 Thecompliant 微观机构不能仅仅提供足够的产量工作而且有足够的刚硬抵抗反应力量并且当保持 thework 片时,维持它的形状。过滤途径的密度也被建议绞链在产生 mechanisms.SIMP 发生消除象棋盘,连接的网孔相关性和一个节点那样的数字不稳定性被用作插值计划显示材料模量的依赖调整 onelement 的密度。顺序的凸的编程方法例如动人的渐近线(MMA ) 的方法,被用来解决优化问题。介绍方法论的确认被一个典型数字例子表明。 | Luo Zhen Du Yixian Chen Liping Yang Jingzhou Karim Abdel-Malek | 2006 | Acta Mechanica Solida Sinica2006，19，1： | 6 |
| 3 | TOPOLOGY SYNTHESIS OF GEOMETRICALLY NONLINEAR COMPLIANT MECHANISMS USING MESHLESS METHODS显示文摘这份报纸用没有元素的 Galerkin 方法(EFGM ) 为几何非线性的顺从的机制的拓扑学优化论述一个新方法。EFGM 作为一个其他的计划被采用数字地由充分在处理大排水量问题利用它的能力解决州的方程。在无网孔的方法,必要边界条件的负担也被探讨。有 penalization (笨人) 的流行地学习的稳固的各向同性的材料计划被用来代表在材料之间的非线性的依赖性质和调整分离密度。当客观功能和伴随方法被用于发现设计功能的敏感,产量排水量被考虑。作为结果,顺从的机制的优化算术地作为一个非线性的编程问题,属于顺序的凸的编程的动人的渐近线(MMA ) 的方法能被用于被建立。现在的方法的可获得性最后与几个广泛地调查的数字例子被表明。 | Yixian Du Liping Chen Zhen Luo | 2008 | Acta Mechanica Solida Sinica2008，21，1： | 3 |
| 4 | Preparation and characterization of polybenzoxazine/trisilanol polyhedral oligomeric silsesquioxanes composites显示文摘 | Wenjie Du Jiajia Shan Yixian Wu Riwei Xu Dingsheng Yu | 2009 | Materials and Design2009，，4： | 1 |
| 5 | A core-satellite structured type Ⅱ heterojunction photocatalyst with enhanced CO_(2) reduction under visible light显示文摘Photocatalytic reduction of carbon dioxide into valuable chemicals is a sustainable and promising technology that alleviates the greenhouse effect and energy crisis.In this study,the Mn_(3)O_(4)/FeNbO_(4) type Ⅱ heterojunction photocatalyst with a core-satellite structure was synthesized by the facile soft chemical method.The formation of a nano-heterojunction is supposed to effectively improve light capture,charge transfer,and interfacial charge separation in the photochemical reaction.Meanwhile,the heterojunction has a good ability to capture and activate CO_(2).Our results show that the prepared Mn_(3)O_(4)/FeNbO_(4) photocatalyst exhibit obvious enhanced catalytic properties in the photocatalytic CO_(2) reduction reaction,where the CH_(4) yielding rate is 1.96 and 9.81 times those of FeNbO_(4) and Mn_(3)O_(4),respectively.The transient photovoltage test(TPV)shows that the low frequency electrons are crucial to the effective transfer of photogenerated electrons and holes in the Mn_(3)O_(4)/FeNbO_(4) nano heterojunctions.Analysis of in situ Fourier transform infrared spectroscopy(FTIR)verifies the effective CO_(2) adsorption on the Mn_(3)O_(4)/FeNbO_(4) surface and the high selectivity of CH_(4) products.These properties of the Mn_(3)O_(4)/FeNbO_(4) photocatalyst infer its broad prospects in the fields of carbon fixation and energy conservation. | Yuanyuan Cheng Yixian Liu Yunliang Liu Yaxi Li Ruqiang Wu Yongchao Du Najmeh Askari Naiyun Liu Fen Qiao Chenghua Sun Zhenhui Kang Haitao Li | 2022 | Nano Research2022，15，10： | 1 |
| 6 | A MODIFIED INTERPOLATION APPROACH FOR TOPOLOGY OPTIMIZATION显示文摘In view of the fact that the follow-up search for an optimal topology is affected by deleting a large number of high-relative-density elements. When the typical density interpolation approach, namely, solid isotropic microstructures with penalization(SIMP), is employed in the continuum structural topology optimization, a new density interpolation approach based on the logistic function is proposed in this paper. This method can weaken low-relative-density elements while enhancing high-relative-density elements by polarization, and then rationally realize polarization of the intermediate density elements. It can reduce the number of gray-scale elements as much as possible to get the optimal topology with distinct boundaries in conjunction with the sensitivity filtering method based on particle swarm optimization(PSO). Several typical numerical examples are given to demonstrate this method. | Yixian Du Shuangqiao Yan Yan Zhang Huanghai Xie Qihua Tian | 2015 | Acta Mechanica Solida Sinica2015，28，4： | 1 |
| 7 | Preparation and characterization of polybenzoxazine/trisilanol polyhedral oligomeric silsesquioxanes composites显示文摘 | Du Wenjie Shan Jiajia Wu Yixian | 2010 | Materials and Design2010，31，4： | 1 |
| 8 | Design and Mechanical Characterization of an S-Based TPMS Hollow Isotropic Cellular Structure显示文摘Cellular structures are regarded as excellent candidates for lightweight-design,load-bearing,and energy-absorbing applications.In this paper,a novel S-based TPMS hollow isotropic cellular structure is proposed with both superior load-bearing and energy-absorbing performances.The hollow cellular structure is designed with Boolean operation based on the Fischer-Koch(S)implicit triply periodic minimal surfaces(TPMS)with different level parameters.The anisotropy and effective elasticity properties of cellular structures are evaluated with the numerical homogenization method.The finite element method is further conducted to analyze the static mechanical performance of hollow cellular structure considering the size effect.The compression experiments are finally carried out to reveal the compression properties and energy-absorption characteristics.Numerical results of the Zener ratio proved that the S-based hollow cellular structure tends to be isotropic,even better than the sheet-based Gyroid TPMS.Compared with the solid counterpart,the S-based hollow cellular structure has a higher elastic modulus,better load-bearing and energy absorption characteristics. | Junjian Fu Pengfei Sun Yixian Du Lei Tian Qihua Tian Xiangman Zhou | 2022 | Computer Modeling in Engineering & Sciences2022，，5： | 0 |
| 9 | Orthogroup and phylotranscriptomic analyses identify transcription factors involved in the plant cold response:Acase study of Arabidopsis BBX29显示文摘C-repeat binding factors(CBFs)are well-known transcription factors(TFs)that regulate plant cold acclimation.RNA sequencing(RNA-seq)data from diverse plant species provide opportunities to identify other TFs involved in the cold response.However,this task is challenging because gene gain and loss has led to an intertwined community of co-orthologs and in-paralogs between and within species.Using orthogroup(closely related homologs)analysis,we identified 10,549 orthogroups in five representative eudicots.A phylotranscriptomic analysis of cold-treated seedlings from eudicots identified 35 high-confidence conserved cold-responsive transcription factor orthogroups(CoCoFos).These 35 CoCoFos included the well-known cold-responsive regulators CBFs,HSFC1,ZAT6/10,and CZF1 among others.We used Arabidopsis BBX29 for experimental validation.Expression and genetic analyses showed that cold-induction of BBX29 is CBF-and abscisic acid-independent,and BBX29 is a negative regulator of cold tolerance.Integrative RNA-seq and Cleavage Under Targets and Tagmentation followed by sequencing analyses revealed that BBX29 represses a set of cold-induced TFs(ZAT12,PRR9,RVE1,MYB96,etc.).Altogether,our analysis yielded a library of eudicot CoCoFos and demonstrated that BBX29 is a negative regulator of cold tolerance in Arabidopsis. | Shuo Wang Yirong Shen Deyin Deng Liangyu Guo Yixian Zhang Yuqi Nie Yunfei Du Xijuan Zhao Xiaoxue Ye Jianqin Huang Huahong Huang Jian-Kang Zhu Wenwu Wu | 2023 | Plant Communications2023，4，6： | 0 |
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