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30篇 您的检索式:作者名="Dudas JR"
    题名 作者 年代 出处 被引量
1A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis显示文摘AIM: To assess the effect of our novel cell-permeable nuclear factor-kappaB (NF-κB) inhibitor peptide PN50 in an experimental model of acute pancreatitis. PN50 was produced by conjugating the cell-penetrating penetratin peptide with the nuclear localization signal of the NF-κB p50 subunit.METHODS: Pancreatitis was induced in male Wistar rats by administering 2×100 μg/kg body weight of cholecystokininoctapeptide (CCK) intraperitoneally (IP) at an interval of 1 h. PN50-treated animals received 1 mg/kg of PN50 IP 30 min before or after the CCK injections. The animals were sacrificed 4 h after the first injection of CCK.RESULTS: All the examined laboratory (the pancreatic weight/body weight ratio, serum amylase activity,pancreatic levels of TNF-α and IL-6, degree of lipid peroxidation, reduced glutathione levels, NF-κB binding activity, pancreatic and lung myeloperoxidase activity) and morphological parameters of the disease were improved before and after treatment with the PN50 peptide.According to the histological findings, PN50 protected the animals against acute pancreatitis by favoring the induction of apoptotic, as opposed to necrotic acinar cell death associated with severe acute pancreatitis.CONCLUSION: Our study implies that reversible inhibitors of stress-responsive transcription factors like NF-κB might be clinically useful for the suppression of the severity of acute pancreatitis.Tamás Letoha Csaba Somlai Tamáas Takács Annamária Szabolcs Katalin Jármay Zoltán Rakonczay Jr Péter Hegyi Ilona Varga József Kaszaki István Krizbai Imre Boros Ern(?) Duda Erzsébet Kusz Botond Penke 2005World Journal of Gastroenterology2005,11,7:15
2Roles of diversifying selection and coordinated evolution in the evolution in the evolution of amphibian antimicrobial peptides显示文摘Duda T F Jr Vanhoye D Nicolas P 0,,:1
3Leporine-derived adipose precursor cells exhibit in vitro osteogenic potential显示文摘Dudas JR Losee JE Penascino VM 2008J Craniofac Surg2008,19,2:1
4Evolutionary Diversification of Multigene Families: Allelic Selection of Toxins in Predatory Cone Snails显示文摘Duda T F Jr Palumbi S R 2000Mol Biol Evol2000,17,:1
5Evolutionary diversification of multigene families: allelic selection of toxins in predatory cone snails 显示文摘Duda TF Jr Palumbi SR 2000Mol Biol Evol2000,17,9:1
6The osteogenic potential of adipose-derived stem cells for the repair of rabbit calvarial defects显示文摘Dudas JR Marra KG Cooper GM Penascino VM Mooney MP Jiang S Rubin JP Losee JE 0,,:1
7Influence of relative binding affinity on efficacy in a panel of anti-CD3 scFv immunotoxins显示文摘Hexham JM Dudas D Hugo R Thompson J King V Dowling C Neville DM Jr Digan ME Lake P 2001Mol Immunol2001,38,5:1
8The anti-inflammatory effect of methylprednisolone occurs down-stream of nuclear factorkappaB DNA binding in acute pancreatitis显示文摘Rakonczay Z Jr Duda E Kaszaki J 2003Eur J Pharmacol2003,464,23:1
9Role of gender and anatomical region on induction of osteogenic differentiation of human adipose-derived stem cells显示文摘Aksu AE Rubin JP Dudas JR 2008Ann Plast Surg2008,60,3:1
10The Addenbrooke's cognitive exami- nation (ACE) in the differential di- agnosis of early dementias versus af- fective disorder 显示文摘Dudas RB Berrios GE Hodges JR 2005Mn J Geriatr Psychiatry2005,13,3:1
11Role of gender and anatomical region on induction of osteogenic differentiation of human adipose-derived stem cells 显示文摘Aksu AE Rubin JP Dudas JR 2008AnnPlastSurg2008,60,3:1
12The osteogenic potential of adipose-dived stem cells for the repair of rabbit calvarial defects显示文摘Dudas JR Marra KG Cooper GM 2006Ann Plast Surg2006,56,5:1
13Role of gender and anatomical region on induction of osteogenic differentiation of human adipose-dierived stem cells显示文摘Aksu AE Rubin JP Dudas JR 2008Ann Plast Surg2008,60,3:1
14Roles of diversifying selection and coordinated evolution in the evolution of amphibian antimicrobial peptides 显示文摘Duda TF Jr Vanhoye D Nicolas P 2002Molecular Biology and Evolu tion2002,19,6:1
15The osteogenic potential of adipose-derived stem cel s for the repair of rabbit calvarial defects显示文摘Dudas JR Marra KG Cooper GM 0,,05:1
16The osteogenic potential of adipose-derived stem cells for the repair of rabbit calvarial defects 显示文摘Dudas JR Marra KG Cooper GM 2006Ann Plast Surg2006,56,5:1
17The osteogenic potential of adipose-derived stem cells for the repair of rabbit calvarial defects 显示文摘Dudas JR Marra KG Cooper GM 2006Ann Plast Surg2006,56,5:1
18Role of gender and anatomical region on induction of estrogenic differentiation of human adipose-derived stem cells显示文摘Aksu AE Rubin JP Dudas JR 2008Ann Plast Surg2008,60,3:1
19Roles of diversifying selection and coordinated evolution in the evolution in the evolution of amphibian antimicrobial peptides 显示文摘DUDA T F Jr VanHOYE D NICOLAS P 2002Mol Biol Evo12002,19,6:1
20The osteogenic potential of adipose-derived stem cells for the repair of rabbit calvarial defects显示文摘Dudas JR Marra KG Cooper GM 2006Ann Plast Surg2006,56,5:1
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