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| 1 | Synthesis of N-methylene phosphonic chitosan(NMPCS)and its potential as gene carder显示文摘N-Methylene phosphoulc chitosan (NMPCS),an amphiphilic macromolecule with powerful chelating ability of Ca^(2+) ions,was synthesized and characterized.The physicochemical properties of NMPCS and the interactions between NMPCS and plasmid DNA were investigated by FTIR,^(13)C NMR,X-ray,agarose gel electrophorcsis retardation assay,atomic force microscopy (AFM) and circular dichroism (CD).The results suggest that at charge ratio 2:1 or above,DNA could be completely entrapped and spherical complexes with mean size of 80-210 nm were formed.Taking HeLa as host cell,luciferase expression mediated by NMPCS improved about 100 times compared to the expression mediated by chitosan. | Dun Wan Zhu Jin Gen Bo Hai Ling Zhang Wen Guang Liu Xi Gang Leng Cun Xian Song Yu Ji Yin Li Ping Song Lan Xia Liu Lin Mei Xiu Lan Li Yang Zhang Kang De Yao | 2007 | Chinese Chemical Letters2007，18，11： | 3 |
| 2 | Is Manipulative Therapy Clinically Necessary for Relief of Neck Pain?A Systematic Review and Meta-Analysis显示文摘Objective:To summarize and critically assess the efficacy of Eastern and Western manipulative therapies for the treatment of neck pain in adults. Methods:A search of Pub Med/MEDLINE, the Cochrane Central Register of Controlled Trials, Clinical Trials.gov, EMBASE, etc. from their inception date to January 2014 with Chinese, Japanese, and Korean databases. Two reviewers independently selected randomized controlled trials(RCTs) with negative control or blank control, extracted data and assessed methodological quality. Meta-analysis and levels of evidence were performed by Revman5.1 and Grades of Recommendations Assessment, Development and Evaluation(GRADE) approach. Results:Nineteen clinical trials with adequate randomization were included in this review, 11 of them had a low risk of bias. The primary outcome for shortterm pain had no significant differences, however, the secondary outcome, only the Numerical Pain Rating Scale(NPRS) score of intermediate-term [n=916, pooled mean differences(MD) =–0.29, P=0.02], the Neck Disability Index(NDI) score of short-term(n=1,145, pooled MD=–2.10, P<0.01), and intermediate-term(n=987, pooled MD=–1.45, P=0.01) were significantly reduced with moderate quality evidence. However, it supported the minimally clinically important difference(MCID) of the Visual Analogue Scale and NPRS pain score to be 13 mm, while NDI was 3.5 points. The meta-analysis only suggested a trend in favor of manipulative therapy rather than clinical significance. Conclusions:The results do not support the existing evidences for the clinical value of Eastern or Western manipulative therapy for neck pain of short-term follow-up according to MCIDs. The limitations of our review related to blinding, allocation concealment and small sample size. | YAO Min SUN Yue-li DUN Rong-liang LAN Tian-ying LI Jin-long Hyo Jin Lee Noriko Haraguchi WANG Yong-jun CUI Xue-jun | 2017 | Chinese Journal of Integrative Medicine2017，23，7： | 2 |
| 3 | Orthonormal Bases Associated with Multi-knot Piecewise Linear Function Sequences on[0,1)~n显示文摘我们为 L 2([0, 调查 orthonormal 底的二个班 1 ) n ) 。那些库的指数的部分是多结片被调用的明智的线性函数光谱序列。我们描绘多结片明智线性光谱序列并且给片的头等的应用明智线性光谱序列。 | Yu Lan LI Dun Yan YAN | 2009 | Acta Mathematica Sinica,English Series2009，25，11： | 1 |
| 4 | L^p(R^n) Boundedness for the Maximal Operator of Multilinear Singular Integrals with Calderón-Zygmund Kernels显示文摘在这篇论文,作者用 standardCalderon-Zygmund 内核考虑最大的多线性的单个不可分的操作符和最大的多线性的摆动的单个不可分的操作符的一个类,并且为 1 在 L^p (R^n ) 上获得他们的围住的海角 < p < ∞。 | Dun Yah YAN Yan MENG Sen Hua LAN | 2005 | Acta Mathematica Sinica,English Series2005，21，3： | 1 |
| 5 | Mechanistic study of the reduction of oxygen in air electrode with manganese oxides as electrecatalysts 显示文摘 | Mao Lan Qun Zhang Dun Tadashi Sotomura | 2003 | Electrochimica Acta2003，48，8： | 1 |
| 6 | High-quality manufacturing method ofcomplicated castings based on multi-materialhybrid moulding process显示文摘A multi-material hybrid patternless moulding process for complicated castings has been proposed. Moulding sands used in the hybrid moulding process include silica sand, ceramic sand, chromite sand, zircon sand, and steel shot sand. Experimental method was used to study the effects of moulding sands on the temperature field, mechanical properties, and dimensional precision of the iron castings. Under the condition that the wall thickness on different sides of the casting is the same, when the wall thickness is greater than 10 mm, the heat storage capacity of the moulding sands from strong to weak is steel shot sand, zircon sand, chromite sand, ceramic foundry sand, and silica sand. Tensile strength of the obtained castings from high to low is zircon sand, chromite sand, steel shot sand, ceramic sand, and silica sand. Contraction rate of the obtained castings from high to low is steel shot sand, zircon sand, chromite sand, silica sand, and ceramic sand. Therefore, steel shot sand and zircon sand can be used as chilled sand, and even can be used instead of cold iron when the casting wall thickness is greater than 10 mm. Zircon sand and chromite sand can be used to obtain high mechanical properties, and silica sand and ceramic sand can be selected to obtain high dimensional precision of the castings. Finally, a typical iron casting piece was tested by experiment using the hybrid moulding process. Excellent performances of iron castings confirm the feasibility of the hybrid moulding process. | Li-min Liu Zhong-de Shan Feng Liu Dun Lan | 2018 | China Foundry2018，15，5： | 1 |
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