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| 1 | Combination strategies to enhance antitumor ADCC显示文摘 | Holbrook E Kohrt Roch Houot Auré lien Marabelle Hearn Jay Cho Keren Osman Matthew Goldstein Ronald Levy Joshua Brody | 2012 | Immunotherapy2012，，5： | 2 |
| 2 | Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging显示文摘BACKGROUND Chronic cocaine use is associated with stroke, coronary artery disease and myocardial infarction, resulting in severe impairments or sudden mortality. In the absence of clear cardiovascular symptoms, individuals with cocaine use disorder (iCUD) seeking addiction treatment receive mostly psychotherapy and psychiatric pharmacotherapy, with no attention to vascular disease (i.e., atherosclerosis). Little is known about the pre-clinical signs of cardiovascular risk in iCUD and early signs of vascular disease are undetected in this underserved population. AIM To assess inflammation, plaque burden and plaque composition in iCUD aiming to detect markers of atherosclerosis and vascular disease. METHODS The bilateral carotid arteries were imaged with positron emission tomography/magnetic resonance imaging (PET/MRI) in iCUD asymptomatic for cardiovascular disease, healthy controls, and individuals with cardiovascular risk. PET with 18F-fluorodeoxyglucose (18F-FDG) evaluated vascular inflammation and 3-D dark-blood MRI assessed plaque burden including wall area and thickness. Drug use and severity of addiction were assessed with standardized instruments. RESULTS The majority of iCUD and controls had carotid FDG-PET signal greater than 1.6 but lower than 3, indicating the presence of mild to moderate inflammation. However, the MRI measure of wall structure was thicker in iCUD as compared to the controls and cardiovascular risk group, indicating greater carotid plaque burden. iCUD had larger wall area as compared to the healthy controls but not as compared to the cardiovascular risk group, indicating structural wall similarities between the non-control study groups. In iCUD, wall area correlated with greater cocaine withdrawal and craving. CONCLUSION These preliminary results show markers of carotid artery disease burden in cardiovascular disease-asymptomatic iCUD. Broader trials are warranted to develop protocols for early detection of cardiovascular risk and preventive intervention in iCUD. | Keren Bachi Venkatesh Mani Audrey E Kaufman Nadia Alie Rita Z Goldstein Zahi A Fayad Nelly Alia-Klein | 2019 | World Journal of Radiology2019，11，5： | 2 |
| 3 | Temperature - regulated bleaching and lysis of the coral Pocillopora damicornis by the novel pathogen Vibrio coralliilyticus显示文摘 | Ben - Haim Y Zicherman - Keren M Rosenberg E | 2003 | Appl Environ Microbiol2003，69，： | 1 |
| 4 | Temperature-regulated bleaching and lysis of the coral Pocillopora damicornis by the novel pathogen Vibrio coralliilyticus显示文摘 | Ben-Haim Y Zicherman Keren M Rosenberg E | 2003 | Applied and Environmental Microbiology2003，69，7： | 1 |
| 5 | Measurements of temperature distribution of flames by moire deflectometry显示文摘 | Keren E Bar-Ziv E Glatt I | | 0，，24： | 1 |
| 6 | Resilience of the internet to random breakdowns 显示文摘 | Reuven C Keren E Daniel B | 2000 | Physical Review Letters2000，85，： | 1 |
| 7 | Encryption of pictures and shapes by random grids显示文摘 | Kafri O Keren E | 1987 | Optics Letters1987，12，6： | 1 |
| 8 | Breakdown of the internet under intentional attack显示文摘 | Reuven C Keren E Daniel B | 2001 | Physical Review Letters2001，86，： | 1 |
| 9 | Treatment of refractory,symptomatic,hepatitis C virus related mixed cryoglobulinemia with ribavirin and interferon-alpha显示文摘 | Zuckerman E Keren D Slobodin G | 2000 | Rheumatology2000，27，9： | 1 |
| 10 | Secretory immunoglobulin A response to Shiga toxin in rabbits : kinetics of the initial mucosal immune response and inhibition of toxicity in vitro and in vivo 显示文摘 | KEREN D F BROWN J E McDONALD R A | 1989 | Infect Immun1989，57，6： | 1 |
| 11 | Encryption of pictures and shaped by random grids 显示文摘 | KAFRI O KEREN E | 1987 | Optics Letters1987，12，6： | 1 |
| 12 | Patterned DNA metallization by sequence-specific localization of a reducing agent显示文摘 | Keren K Berman R S Braun E | 2004 | Nano Letters2004，4，2： | 1 |
| 13 | Patterned DNA metallization by se- quence-specific localization of a reducing agent 显示文摘 | Keren K Berman RS Braun E | 2004 | Nano letters2004，4，2： | 1 |
| 14 | DNA-templated carbon nanotube field-effect transistor显示文摘 | Keren K Berman R S Bucbstab E | 2003 | Science2003，302，5649： | 1 |
| 15 | Measurements of temperature distribution of flames by moiré deflectometry显示文摘 | E KEREN E BAR-ZIV I GLATT | 1981 | Applied Optics1981，20，24： | 1 |
| 16 | Antiangiogenic antitumor activity of HPMA Copolymer-Paclitaxel-Alendmnate conjugate on breast cancer bone metastasis mouse model 显示文摘 | Keren M Anat E B Dina P | 2011 | Molecular Pharmaeeutics2011，4，8： | 1 |
| 17 | ldentifying newborns at risk of significant hyperbilirubinaemia:a comparison of two recommended approaches显示文摘 | Keren E Bhutani VK Luan X | 2005 | Archives of Disease in Childhood2005，90，4： | 1 |
| 18 | Secretory im-munoglobulin A response to Shiga toxin in rabbits:kinetics of the initial mucosal immune response and inhibition of toxicity in vitro and in vivo显示文摘 | KEREN D F BROWN J E MCDONALD R A | 1989 | Infect Immun1989，57，： | 1 |
| 19 | Patients aged 80 and older undergoing orthopedic or urologic, surgery: a prospective study focusing on perioperative morbidity and mortality显示文摘 | PELED E KEREN Y HALACHMI S | 2009 | Gerontology2009，55，5： | 1 |
| 20 | Effect of exercise on cerebral circulation显示文摘 | Globus M Melamed E Keren A | 1983 | J Cereb Blood Flow Metab1983，3，： | 1 |
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