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| 1 | Hemoglobin A1c in early postpartum screening of women with gestational diabetes显示文摘AIM:To assess the utility of hemoglobin A1c(HbA1c) in the early postpartum screening of women with gestational diabetes mellitus(GDM).METHODS:Over a 3 years period,HbA1c estimations were undertaken in addition to and simultaneously with the traditional oral glucose tolerance test(OGTT),in 203 women with GDM as a part of early postpartum screening for dysglycaemia,at 6 wk post-partum.World Health Organization criteria was used for diagnosing diabetes:fasting blood glucose(FBG) ≥ 7.0 mmol/Land/or 2-h postprandial blood glucose(PPBG) ≥ 11.1 mmol/L and/or HbA1c ≥ 48 mmol/mol;and impaired glycaemiastate:impaired fasting glucose 6.1-6.9 mmol/L and/or impaired glucose tolerance 7.8-11.0 mmol/L and/or HbA1c:42-47 mmol/mol.RESULTS:Mean FBG,2-h PPBG and HbA1c were 4.9 ± 0.7 mmol/L,5.6 ± 2.0 mmol/L and 38 ± 5 mmol/mol respectively.FBG,2-h PPBG and HbA1c detected 6(3%),7(3.5%) and 11(5.4%) cases of diabetes respectively,and 11(5.4%),25(12.3%) and 23(11.3%) cases of pre-diabetes state respectively.HbA1c values ≥ 48 mmol/mol(≥ 6.5%) showed a diagnostic sensitivity of 71.4% and specificity of 98.5% for diabetes in comparison to OGTT in receiver operating characteristics curve analysis.At HbA1c cut-off 44 mmol/mol,sensitivity and specificity were 100% and 92.3% respectively [area under the curve:0.98(95%CI:0.96-1.00)].Sensitivity and specificity for detecting high risk 'impaired glycaemia' state [HbA1c 42 mmol/mol(6.0%)] were 28% and 80%,respectively.CONCLUSION:HbA1c level ≥ 48 mmol/mol(≥ 6.5%) has reasonable sensitivity and high specificity in comparison to OGTT for early postpartum screening of diabetes in GDM.At 6 th week postpartum screening,if FBG is normal and HbA1c < 44 mmol/mol OGTT is not recommended. | Mahesh V Katreddy Joseph M Pappachan Sarah E Taylor Radha Indusekhar Ananth U Nayak Alan M Nevill | 2013 | World Journal of Diabetes2013，4，3： | 2 |
| 2 | Structural roles of calcium ions and side chains in welan:an X-ray study显示文摘 | Chandrasekaran R Radha A Lee E J | 1994 | Carbohydr Res1994，252，15： | 1 |
| 3 | Structural roles of calcium ions and side chains in welan:an X-ray study显示文摘 | Chandraseksran R Radha A Lee E J | | 0，，： | 1 |
| 4 | Plant regeneration from embryo-derived callus of oil palm-the effect of exogenous polyamines显示文摘 | Rajesh M K Radha E Karun A | 2003 | Plant Cell Tissue and Organ Culture2003，75，1： | 1 |
| 5 | Mining Web data using clustering technique for Web personalization 显示文摘 | Supriya Kumar D E Radha Krishna P | 2002 | International Journal of Computational Intelligence and Applications2002，2，3： | 1 |
| 6 | Plant regeneration from embryo-derived callus of oil palm-the effect of exogenous polyamines显示文摘 | Rajesh M K Radha E Karun A | 2003 | Plant Cell Tissue and Organ Culture2003，75，1： | 1 |
| 7 | Structural roles of calcium ions and side chains in welan: an xray study 显示文摘 | Chandrasekaran R Radha A Lee E J | 1994 | Carbohydr Res1994，252，： | 1 |
| 8 | Unique characteristic features of stimulated Brillouin scattering in small-core photonic crystal fibers显示文摘 | MCEIHENNY J E RADHA K | | 0，，： | 1 |
| 9 | Age-related changes in rat muscle cc)llagen显示文摘 | S Mohan E Radha | 1980 | JBiomech1980，，26： | 1 |
| 10 | Monoamine levels and monomine oxidase activity in differentregions of the rat brain as a function of age显示文摘 | BHASKARAN D RADHA E | 1983 | Mech Aging Dev1983，23，： | 1 |
| 11 | Monoamine levels and monomine oxidase activity in different regions of the rat brain as a function of age 显示文摘 | Bhaskaran D Radha E | 2005 | Mech Aging Dev2005，23，3： | 1 |
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