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4篇 您的检索式:作者名="E.Gonzalez"
    题名 作者 年代 出处 被引量
1可靠的高温测井技术显示文摘Los Alamos国家实验室(LANL)已把地热工程的高温井测井技术改型翻新成适用于深气井套管井测井方法(伽马射线、中子和套管接箍)。实验室的实验表明,这种高温井下井仪器能在400°F(204℃)的井底条件下使工作时间延长3倍。在西俄克拉何马州Beckhom县深气井测井作业期间,标准的套管井测井下井仪器在2~4h内就失效了,而高温井下井仪器成功地进行两个连续的6h(12h)测井作业。在此之后。Manuel(Manny)E.Gonzalez 白梅岭 1996国外油气勘探1996,8,6:1
2Cardiac ischemic preconditioning prevents dystrophin proteolysis by MMP-2 inhibition显示文摘Dystrophin is a membrane-associated protein responsible for structural stability of the sarcolem-ma in cardiac myocytes and is very sensitive to ischemic damage.The goal of our study was to determine if ischemic preconditioning could prevent dystrophin breakdown through inhibition of matrix metalloprotein-ase-2(MMP-2)activity.Isolated rabbit hearts were subjected to global ischemia with or without reperfusion in order to evaluate if dystrophin is preserved by ischemic preconditioning through MMP-2 inhibition.Ischemic preconditioning significantly reduced the infarct size induced by 30 min of ischemia and 180 min of reperfusion.Importantly,it also diminished dystrophin proteolysis and attenuated MMP-2 activity after 30 min ischemia.Thus,our study shows a novel protective role of ischemic preconditioning as a mechanism of preservation of plasma membrane integrity by inhibiting MMP-2 activation.MANUEL RODRIGUEZ BRUNO BUCHHOLZ VERONICA D'ANNUNZIO MARTÍN DONATO GERMAN E.GONZALEZ MARIA AILIN GOYENECHE TAMARA MAZO VIRGINIA PEREZ LUCIANA WILENSKY RICARDO J.GELPI 2016BIOCELL2016,40,1:0
3Evaluation of activity of triclabendazole against Taenia solium metacestode in naturally infected pigs显示文摘Objective:To assess the efficacy of triclabendazole(TCBZ) in porcine cysticercosis.Methods:Eighteen naturally infected cysticercotic pigs were divided into 3 groups of 6 individuals each.The first group was treated orally with TCBZ at a single dose of 30 mg/kg of body weight,the second group was treated orally with oxfendazole at a single dose of 30 mg/kg of body weight and the third group received a placebo(control group).All animals were kept under the same management conditions.The pigs were euthanized 17 wk post-treatment and the number of surviving cysts in muscles was assessed and compared between groups.Results:All pigs treated with oxfendazole had only degenerated cysts in their carcasses.In contrast,TCBZ had very little effect against the parasitic cysts.Cysts from pigs in the TCBZ group looked apparently normal after treatment.However,histological evaluation showed a mild to moderate degree of inflammation.Conclusions:TCBZ is not an efficacious drug against Taenia solium cysticercosis in swine using a single dose.Ana Vargas-Calla Luis A.Gomez-Puerta Juan Calcina Omar Gonzales-Viera Cesar Gavidia Maria T.Lopez-Urbina Hector H.Garcia Armando E.Gonzalez 2016Asian Pacific Journal of Tropical Medicine2016,9,1:0
4古巴共和国的结核病:可能被消除显示文摘背景:多数发达国家都把消除结核病作为首要任务,尽管其中有些国家因AIDS病流行和耐药性而遭受困挠。发展中国家的结核病则是更严重的问题。目的:通过对1979—1991年期间新报告病例趋势按临床类型和年龄组的分析评价古巴结核病流行病学形势。设计:以简单回归模式用于从国家监测系统获得的‘新病例’率的时间系列资料。估算每年变化百分比。结果:1979—91年结核病下降59.5%(从11.6下降到4.7/100000人口/年)。下降发生于所有年龄组;1991年新病例的60%属于45岁及以上,其中3O%为65岁及以上。结核分支杆菌菌株耐药性(1989年为2.49%)仍少见,全民中HIV感染(1991年为0.009%)亦罕见。结论:除良好的耐药性趋势和全民中低HIV感染之外,迄今报告的新病例数持续稳定的下降表示国家结核病控制规程今后仍将确实可能保持其有效性,从而有理由制订消除结核病的新战略。E.Gonzalez L.Armas A.Alonso 何汉清 1995国际结核病与肺部疾病杂志1995,0,1:0
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