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| 1 | Genomic and genetic alterations influence the progression of gastric cancer显示文摘Gastric cancer is one of the leading causes of cancerrelated deaths worldwide, although the incidence has gradually decreased in many Western countries. Two main gastric cancer histotypes, intestinal and diffuse, are recognised. Although most of the described genetic alterations have been observed in both types, different genetic pathways have been hypothesized. Genetic and epigenetic events, including 1q loss of heterozygosity (LOH), microsatellite instability and hypermethylation, have mostly been reported in intestinal-type gastric carcinoma and its precursor lesions, whereas 17p LOH, mutation or loss of E-cadherin are more often implicated in the development of diffuse-type gastric cancer.In this review, we summarize the sometimes contradictory findings regarding those markers which influence the progression of gastric adenocarcinoma. | Stefania Nobili Lorenzo Bruno Ida Landini Cristina Napoli Paolo Bechi Francesco Tonelli Carlos A Rubio Enrico Mini Gabriella Nesi | 2011 | World Journal of Gastroenterology2011，17，3： | 17 |
| 2 | 超滤对血橙果汁中抗氧化成分及总抗氧化能力的影响显示文摘采用管式聚偏氟乙烯(PVDF)超滤膜,探讨了超滤对血橙果汁中抗氧化成分及总抗氧化能力的影响。结果表明,其对维生素C和花青素类成分的保存率约为85%左右,对几种酚酸和类黄酮组分(除槲皮素外)的保存率均在90%以上。同未杀菌的血橙原汁相比,巴氏杀菌汁的总抗氧化能力(TAA)损失率为23%,而超滤澄清汁仅为10%左右,主要与维生素C和花青素含量损失有关。 | 苏学素 焦必宁 陈宗道 A lfredo Cassano Enrico Drioli | 2004 | 农业工程学报2004，20，2： | 7 |
| 3 | Fulminant myocarditis in adults: a narrative review显示文摘Fulminant myocarditis(FM)is an uncommon syndrome characterized by sudden and severe hemodynamic compromise secondary to acute myocardial inflammation,often presenting as profound cardiogenic shock,life-threatening ventricular arrhythmias and/or electrical storm.FM may be refractory to conventional therapies and require mechanical circulatory support(MCS).The immune system has been recognized as playing a pivotal role in the pathophysiology of myocarditis,leading to an increased focus on immunosuppressive treatment strategies.Recent data have highlighted not only the fact that FM has significantly worse outcomes than non-FM,but that prognosis and management strategies of FM are heavily dependent on histological subtype,placing greater emphasis on the role of endomyocardial biopsy in diagnosis.The impact of subtype on severity and prognosis will likewise influence how aggressively the myocarditis is managed,including whether MCS is warranted.Many patients with refractory cardiogenic shock secondary to FM end up requiring MCS,with venoarterial extracorporeal membrane oxygenation demonstrating favorable survival rates,particularly when initiated prior to the development of multiorgan failure.Among the challenges facing the field are the need to more precisely identify immunopathophysiological pathways in order to develop targeted therapies,and the need to better optimize the timing and management of MCS to minimize complications and maximize outcomes. | Santiago Montero Darryl Abrams Enrico Ammirati Florent Huang Dirk WDonker Guillaume Hekimian Cosme García-García Antoni Bayes-Genis Alain Combes Matthieu Schmidt | 2022 | Journal of Geriatric Cardiology2022，19，2： | 3 |
| 4 | Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification显示文摘AIM To undertook a systematic review to determine factors that increase a patient's risk of developing lower limb periprosthetic joint infections(PJI).METHODS This systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors. Studies were only included if they included greater than 20 patients in their study cohort, and there was clear documentation of the statistical parameter used; specifically P-value, hazard ratio, relative risk, or/and odds ratio(OR). Furthermore a quality assessment criteria for the individual studies was undertaken to evaluate the presence of record and reporting bias. RESULTS Twenty-seven original studies reviewing risk factors relating to primary total hip and knee arthroplasty infections were included. Four studies(14.8%) reviewed PJI of the hip, 3(11.21%) of the knee, and 20(74.1%) reviewed both joints. Nineteen studies(70.4%) were retrospective and 8(29.6%) prospective. Record bias was identified in the majority of studies(66.7%). The definition of PJI varied amongst the studies but there was a general consensus to define infection by previously validated methods. The most significant risks were the use of preoperative high dose steroids(OR = 21.0, 95%CI: 3.5-127.2, P < 0.001), a BMI above 50(OR = 18.3, P < 0.001), tobacco use(OR = 12.76, 95%CI: 2.47-66.16, P= 0.017), body mass index below 20(OR = 6.00, 95%CI: 1.2-30.9, P = 0.033), diabetes(OR = 5.47, 95%CI: 1.77-16.97, P = 0.003), and coronary artery disease(OR = 5.10, 95%CI: 1.3-19.8, P = 0.017).CONCLUSION We have highlighted the need for the provider to optimise modifiable risk factors, and develop strategies to limit the impact of non-modifiable factors. | David A George Lorenzo Drago Sara Scarponi Enrico Gallazzi Fares S Haddad Carlo L Romano | 2017 | World Journal of Orthopedics2017，8，5： | 3 |
| 5 | 具有不确定参数的温度传感器的动态相对校准(英文)显示文摘存在动态偏差情况下的传感器校准,与多个传感器的相对校准类似.实现相对校准对许多控制问题都很重要,比如需要产生精确温度梯度的问题、保持均匀与稳定温度场的问题.本文以温度传感器为例,对静态(稳态)校准与动态校准从理论和实验两个角度进行了对比.动态校准的一个优势是其适用于任何测量数据,但其需要建立一个测量仪器的动态模型.尽管本文只研究了一个由三个传感器构成的简单设备,但其结果也适用于更复杂的情况.这正是因为动态校准的另一个显著优势,即其能在任何设备上进行校准,校准的一个前提是所用的动态模型与传感器具有相同的阶次.本文证明了可辨识性(可校准性)条件,并通过以迭代方式求解一个非线性加权最小二乘问题,实现了校准.对解的收敛性、一致性和渐近效率,不但给予了理论证明,且通过蒙特卡罗模拟实验进行了验证. | Canuto Enrico Ospina José A Acuna-Bravo Wilber | 2012 | 中国科学技术大学学报2012，42，5： | 2 |
| 6 | Toward a new generation ofsemantic Web applications 显示文摘 | Enrico M Marta S Sofia A | 2008 | IEEE intelligent systems2008，23，3： | 1 |
| 7 | How to increase the proportion of hysterectomies vaginally显示文摘 | Enrico Vizza B Bournas N | 1998 | Am J Obstet Gynecol1998，179，4： | 1 |
| 8 | Neutrophil funcation and humoral immunity in children with recurrent infections of the lower respiratory tract and chronic bronchial supparation显示文摘 | Giantonioc C Enrico A Stefano C | 1989 | Ann Allergy1989，63，： | 1 |
| 9 | Optimization strategies for electrospun silk fibroin tissue engineering scaffolds显示文摘 | MEINEL A J KUBOW K E Klotzsch Enrico | 2009 | Biomaterials2009，30，： | 1 |
| 10 | Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial显示文摘 | Claudio Bassi Massimo Falconi Enrico Molinari William Mantovani Giovanni Butturini Andrew A Gumbs Roberto Salvia Paolo Pederzoli | 2003 | Surgery2003，，5： | 1 |
| 11 | Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma显示文摘 | A H Enrico G Mallika S | 2003 | Cancer Cell2003，4，5： | 1 |
| 12 | Augmenter of liver regeneration (ALR) protects human hepatocytes against apoptosis显示文摘 | Ilowski M Kleespies A Enrico NT | 2011 | Biochim Biophys Res Com2011，404，1： | 1 |
| 13 | The kinetics of gibbsite dissolution in NaOH显示文摘 | JANANA A M PEREIRA MARCIO SCHWAAB ENRICO DELL'ORO | 2009 | Hydrometallurgy2009，96，12： | 1 |
| 14 | Neonatal morbidity in growth-discordant monoehorionic twins: comparison be- tween the larger and the smaller twin显示文摘 | Enrico L Carolien S Suzanne A | 2012 | Twin Research and Human Genetics2012，15，4： | 1 |
| 15 | Cerium-based chemical conversion coating on AZ-63 magnesium alloy显示文摘 | Manuele Dabala'a Katya Brunellia Enrico Napolitanib | 2003 | Surf coat technol2003，177，： | 1 |
| 16 | Parenchymal abnormalities associated with developmental venous anomalies显示文摘 | Diego San Millán Ruíz Jacqueline Delavelle Hasan Yilmaz Philippe Gailloud Enrico Piovan Alberto Bertramello Francesca Pizzini Daniel A Rüfenacht | 2007 | Neuroradiology2007，，12： | 1 |
| 17 | Comparison of Methods to Estimate the Time-to-Failure Distribution in Degradation Tests 显示文摘 | Viviane R B Enrico A C | 2004 | Quality and Reliability engineering International2004，20，4： | 1 |
| 18 | Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure 显示文摘 | Igor B Francesca C Enrico A | 2003 | Neurotoxicology2003，24，3： | 1 |
| 19 | Association betweenhistologic type of polyp and carcinoma in the stomach显示文摘 | Enrico GC Stefano A Giovanni BB | 1992 | Gastrointest Endosc1992，38，4： | 1 |
| 20 | Pre liminary results of serum androgen level testing in man with rheumatoid arthritis 显示文摘 | ENRICO B SILVANO A ELPIS S MARCO AC | 1984 | Arthritis Rheum1984，27，： | 1 |
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