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| 1 | A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species显示文摘Quantitative trait loci(QTL)mapping approaches rely on the correct ordering of molecular markers along the chromosomes,which can be obtained from genetic linkage maps or a reference genome sequence.For apple(Malus domestica Borkh),the genome sequence v1 and v2 could not meet this need;therefore,a novel approach was devised to develop a dense genetic linkage map,providing the most reliable marker-loci order for the highest possible number of markers.The approach was based on four strategies:(i)the use of multiple full-sib families,(ii)the reduction of missing information through the use of HaploBlocks and alternative calling procedures for single-nucleotide polymorphism(SNP)markers,(iii)the construction of a single backcross-type data set including all families,and(iv)a two-step map generation procedure based on the sequential inclusion of markers.The map comprises 15417 SNP markers,clustered in 3 K HaploBlock markers spanning 1267 cM,with an average distance between adjacent markers of 0.37 cM and a maximum distance of 3.29 cM.Moreover,chromosome 5 was oriented according to its homoeologous chromosome 10.This map was useful to improve the apple genome sequence,design the Axiom Apple 480 K SNP array and perform multifamily-based QTL studies.Its collinearity with the genome sequences v1 and v3 are reported.To our knowledge,this is the shortest published SNP map in apple,while including the largest number of markers,families and individuals.This result validates our methodology,proving its value for the construction of integrated linkage maps for any outbreeding species. | Erica A Di Pierro Luca Gianfranceschi Mario Di Guardo Herma JJ Koehorst-van Putten Johannes W Kruisselbrink Sara Longhi Michela Troggio Luca Bianco Hélène Muranty Giulia Pagliarani Stefano Tartarini Thomas Letschka Lidia Lozano Luis Larisa Garkava-Gustavsson Diego Micheletti Marco CAM Bink Roeland E Voorrips Ebrahimi Aziz Riccardo Velasco François Laurens W Eric van de Weg | 2016 | Horticulture Research2016，3，1： | 3 |
| 2 | Effects of herbivory on the reproductive effort of 4 prairie显示文摘 | Erica S Kate L B Johannes M H K | 2002 | BMC Ecology2002，2，： | 1 |
| 3 | Impact on the quality of lift of patients with arteriovenous malformation during the latent interval between gamma knife radiosurgery and lesion obliteration显示文摘 | Samuel C | 2002 | J Neurosurg2002，97，5： | 1 |
| 4 | Detection and Quantification of the Red Tide Dinoflagellate Karenia brevis by Real-Time Nucleic Acid Sequence-Based Amplification显示文摘 | Erica T Casper John H Paul Matthew C Smith | 2004 | Applied and environmental microbiology2004，70，8： | 1 |
| 5 | Investigating the Antimalarial Action of 1,2 ,4-Trioxolanes with Fluorescent ChemicalProbes显示文摘 | Carmony L H Erica M W L Sumit S M | 2011 | J Med Chem2011，54，23： | 1 |
| 6 | Impact on the quality of life of patients with arteriovenous malformation during the latent interval between gamma knife radiosurgery and lesion obliteration显示文摘 | ERICA H SAMUEL C | 2002 | J Neurosurg2002，97，5： | 1 |
| 7 | Inflammation enhances myeloid-derived suppressor cell crosstalk by signaling through Toll-like receptor 4显示文摘 | STEPHANIE K B VIRGINIA K C ERICA M H | 2009 | J Leukoc Biol2009，85，： | 1 |
| 8 | MDR1(ABCB1) G1199A(Ser400Asn) polymorphism alters transepithelial permeability and sensitivity to anticancer agents显示文摘 | Erica L Matthew H Crouthamel H | 2009 | Cancer Chemother Pharmacol2009，64，23： | 1 |
| 9 | Plasticity of marrow-derived stem cells显示文摘 | Erica L H Li C Diane S K | 2003 | Blood2003，102，： | 1 |
| 10 | Duffy-null promoter heterozygosity reduces DARC expression and abrogates adhesion of the P. vivax ligand required for blood-stage infection显示文摘 | Pascal Michon Ian Woolley Erica M Wood W Kastens Peter A Zimmerman John H Adams | 2001 | FEBS Letters2001，，1： | 1 |
| 11 | Rethinking the role of the state in technology development: DARPA and the case for embed- ded network governance 显示文摘 | ERICA R H FUCHS | 2010 | Research Policy2010，，39： | 1 |
| 12 | Strategicmaterials selection in the automobile body: Economic opportunities for polymer composite design 显示文摘 | Erica R H Fuchs Frank R Field Richard Roth | 2008 | Composites Science and Tech- nology2008，68，9： | 1 |
| 13 | The relative safety of an oxygenator显示文摘 | Soren H Erica J | 1997 | Perfusion1997，12，： | 1 |
| 14 | Cultural Factors in Social Anxiety: A Comparison of Social Phobia Symptoms aand Taijin Kyofusho显示文摘 | Dinnel D L Erica E H N | 1997 | Journal of Anxiety Disorders1997，11，2： | 1 |
| 15 | Plasticity of marrow - derived stem cells显示文摘 | ERICA L H LI C DIANE S K | 2003 | Blood2003，102，12： | 1 |
| 16 | Scientific mis- conduct from the perspective of research coordinators : a na- tional survey显示文摘 | ERICA R P BARBARA H MARION E B | 2007 | Med Ethics2007，，33： | 1 |
| 17 | Prognostic risk stratification and clinical outcomes in patients undergoing surgical treatment for renal cell carcinoma with vascular tumor thrombus显示文摘 | Erica H L Phillip MP Ahmad S | 2007 | Urology2007，69，6： | 1 |
| 18 | Paerimatal risks associated tith borderline amniotic fluid index显示文摘 | Erica H Banks MD David A | 1999 | Am J Obstet Gynecol1999，180，6： | 1 |
| 19 | Dietary lutein reduces ultraviolet radiation-induced inflammatic and immunosup- pression 显示文摘 | Lee Erica H Faulhaber Dorothea Hanson Kerry M | 2004 | The Journal of Investigative Dermatology2004，，2： | 1 |
| 20 | Effect of myristoylated alanine-rich C-kinase substrate, MARCKS over expression on hippocampus-dependent learning and hippocampal synaptic plasticity in MARCKS transgenic mice 显示文摘 | ROBERT K M RIFAT J H ERICA J S | 2005 | Hippocampus2005，15，5： | 1 |
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