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| 1 | The circulating non-coding RNA landscape for biomarker research: lessons and prospectsfrom cardiovascular diseases显示文摘人的染色体的弥漫的抄写为无数非编码的 RNA 分子(ncRNAs ) 的生产负责有规章的功能的他们的一些。在心血管的生物学的 ncRNAs 的枢轴的角色在最后十年被揭开了,从在心血管的开发和功能的 micro-RNAs 的参与的描述开始,并且作为心血管的疾病的 biomarkers 由传播 ncRNAs 的使用列在后面。人的非编码的 secretome 被几 RNA 种填写在身体液体传播并且能为诊断和结果预言被用作 biomarkers。在心血管的疾病,分泌了 ncRNAs 包括心肌的梗塞,心脏的失败,和 atrial 纤维性颤动被描述了为几个条件的 biomarkers。在传播之中, ncRNAs, micro-RNAs (miRNAs ) ,长 noncoding RNA (lncRNAs ) 和圆形的 RNA (circRNAs ) 在不同心血管的疾病作为 biomarkers 被建议了。与标准 biomarkers 比较, ncRNAs 的生物化学的性质为更好的稳定性和灵活存储提供样品,和增加的敏感和特性的条件。在这评论,我们把当前的趋势和 ncRNA secretome 部件的使用的未来前景描述为心血管的疾病的 biomarkers,包括与他们的分泌物机制和规章的行动联系的开的问题。 | Ewa STFPIEN Marina C COSTA Szczepan KURC Anna DROZDZ Nuno CORTEZ-DIAS Francisco J ENGUITA | 2018 | Acta Pharmacologica Sinica2018，39，7： | 14 |
| 2 | Neutrophil engagement and septic challenge in acute experimental pancreatitis in rats显示文摘AIM: To investigate the influence of neutrophil adhesion molecule blockade with monoclonal antibody (MoAb CD11b) and E. coli lipopolysaccharide (LPS)administration on experimental acute pancreatitis (AP).METHODS: AP was induced by four ip injections of cerulein (Cn) at 1-h intervals. MoAb CD 11b and LPS were administered at the beginning of the experiment.RESULTS: The neutrophil count and chemiluminescence were diminished at the beginning of AP. The oxidative stress parameters were found within the pancreatic gland. MoAb CD 11b used for AP resulted in a significant reduction of pancreatic infiltration and pancreatitis oxidative stress parameters. Serum interleukin-6 (IL-6)was not detected in AP animals, whereas high serum IL-6 concentration was noted only in animals receiving LPS.CONCLUSION: Neutrophils are involved in pancreatic damage in the early stage of AP. Neutrophil infiltration reduction protects the pancreatic gland from destruction during AP. LPS does not change the early course of Cn pancreatitis in rats. | Stanisiaw Ha Marek Dobosz Jan J Kaczor Robert Rzepko Ewa Aleksandrowicz-Wrona Zdzislaw Wajda Zbigniew ledzi■ski Jacek Krajewski | 2005 | World Journal of Gastroenterology2005，11，41： | 7 |
| 3 | Effects of Rhodiola rosea supplementation on mental performance,physical capacity,and oxidative stress biomarkers in healthy men显示文摘Purpose: The objective of this study was to investigate the effects of chronic Rhodiola rosea(R. rosea) supplementation on mental and physical performance, as well as hormonal and oxidative stress biomarkers.Methods: Twenty-six healthy male students received either R. rosea extract(600 mg/day; RR) or placebo(PL) in a randomized double-blind trial. Prior to supplementation(Term I) and following 4 weeks of supplementation(Term II), the students underwent psychomotor tests for simple and choice reaction time, included in the Vienna Test System. Also, the subjects performed VO2 peaktest. Blood samples were obtained before and after the test to measure the hormonal profile(cortisol, testosterone, and growth hormone), as well as the biomarkers of oxidative stress(lipid hydroperoxides, total antioxidant capacity, and superoxide dismutase) and muscle damage(creatine kinase).Results: R. rosea ingestion shortened reaction time and total response time. Moreover, a greater relative increase in the number of correct responses was observed in RR group as compared to the PL group. No changes in endurance exercise capacity and hormonal profile were observed after R. rosea ingestion. R. rosea ingestion raised plasma total antioxidant capacity. It did not, however, affect other measured parameters.Conclusion: Chronic R. rosea ingestion does not affect physical performance, but can improve the results of some psychomotor tests(simple and choice reaction time) in young, healthy, and physically active men. The improvements in mental performance, however, at least in our study,seem not to be related to changes in cortisol release or antioxidant activity of R. rosea extract. Thus, the specific mechanisms responsible for these effects still need to be elucidated. | ewa jówko jerzy sadowski barbara dlugolecka dariusz gierczuk benedykt opaszowski igor ciesliński | 2018 | Journal of Sport and Health Science2018，7，4： | 2 |
| 4 | Anticonvulsant and acute neurotoxic effects of imperatorin,osthole and valproate in the maximal electroshock seizure and chimney tests in mice:A comparative study显示文摘 | Jarogniew J Luszczki Ewa Wojda Marta Andres-Mach | 2009 | Epilepsy Res2009，85，23： | 1 |
| 5 | Ant hracycline-in-duced cardiotoxicity:clinical course,risk factors,pat hogenesis,detection and prevention-review of the literature显示文摘 | J anusz W Ewa L N Krzysztof L K | 2000 | Med Sci Monit2000，6，2： | 1 |
| 6 | The diagnostic and therapeutic difficulties of the recurrent lower respiratory tract infections in children with neurological disorders 显示文摘 | Ewa J Bosena K D Ewa G | 2011 | Pediatria Polska2011，86，5： | 1 |
| 7 | Key Role of flt3 Ligand in Regulation of the Common Lymphoid Progenitor but Not in Maintenance of the Hematopoietic Stem Cell Pool显示文摘 | Ewa Sitnicka David Bryder Kim Theilgaard-M?nch Natalija Buza-Vidas J?rgen Adolfsson Sten Eirik W Jacobsen | 2002 | Immunity2002，，4： | 1 |
| 8 | Upregulation of Flt3 Expression within the Bone Marrow Lin ? Sca1 + c-kit + Stem Cell Compartment Is Accompanied by Loss of Self-Renewal Capacity显示文摘 | J?rgen Adolfsson Ole Johan Borge David Bryder Kim Theilgaard-M?nch Ingbritt ?strand-Grundstr?m Ewa Sitnicka Yutaka Sasaki Sten E.W Jacobsen | 2001 | Immunity2001，，4： | 1 |
| 9 | Human leukocyte antigens class Ⅱ and tumor necrosis factor genetic Polymorphisms are independent predictors of non-Hodgkin lymphoma outcome 显示文摘 | Przemyslaw J Ewa K Jacques B | 2002 | Blood2002，100，： | 1 |
| 10 | Carbon and phosphorus transformations in a full-scale enhanced biological phosphorus removal process显示文摘 | Ewa L Magnus C Karin J | 1997 | Water Res1997，11，31： | 1 |
| 11 | Infectivity of blood products from donors with occult hepatitis B virus infection显示文摘 | Jean‐Pierre Allain Ivanka Mihaljevic Maria Isabel Gonzalez‐Fraile Knut Gubbe Lene Holm‐Harritsh?j Jose Maria Garcia Ewa Brojer Christian Erikstrup Mona Saniewski Lorenz Wernish Lydia Bianco Henrik Ullum Daniel Candotti Nico Lelie Wolfram H. Gerlich Michae | 2013 | Transfusion2013，，7： | 1 |
| 12 | Rare earth element patterns in Nigerian coals显示文摘 | ELEGBA S B ADETUNJI J | 1996 | J Radioanal Nucl Chem1996，213，3： | 1 |
| 13 | Increasing substrate for polyphosphate-accumulating bacteria in municipal wastewater through hydrolysis and fermentation of sludge in primary clarifiers 显示文摘 | Magnus C Ewa L Karin J | 1998 | Water Environ Res1998，70，2： | 1 |
| 14 | Mulberry leaf extract intake reduces hyperglycaemia in streptozotocin (STZ)-induced diabetic rats fed high-fat diet显示文摘 | Magdalena JS Ewa F Jan J | 2014 | Journal of Functional Foods2014，，： | 1 |
| 15 | Characterization of an acous-to-optic tunable filter and use in visible spectrophotometry显示文摘 | Bucher Ewa G Carnahan J W | 1999 | Applied Spectroscopy1999，53，5： | 1 |
| 16 | Ant hracycline induced cardiotoxicity:clinical course,risk factors,pathogenesis,detection and prevention review of the literature显示文摘 | J anusz W Ewa LN Krzysztof LK | 2000 | Med Sci Monit2000，6，2： | 1 |
| 17 | Difficulties in differentiation of Parry-Romberg syndrome,unilateral facial sclerodermia, and Rasmussen syndrome显示文摘 | JUSTYNA P EWA J DARIUSZ A | 2006 | Childs Nerv Syst2006，22，： | 1 |
| 18 | Carbon and phosphorus transformations in a full-scale enhanced biological phosphorus removal process 显示文摘 | Ewa L Magnus C Karin J | 1997 | Water Research1997，31，11： | 1 |
| 19 | Early-phase im-munodetection of me tallothio- nein and heat shock proteins in ex-truded earthworm coelomocytes after d ermal expo- sure tometalions显示文摘 | Homa J Olchawa Ewa Sturzenbaum S R | 2005 | Environ Pollut2005，135，2： | 1 |
| 20 | Nanoeomposite of cement/graphene oxide--Impact on hydration ki- netics and Young's modulus显示文摘 | El2bieta Horszczaruk Ewa Mijowska Ryszard J Kalenczuk | 2015 | Construction Building Mater2015，78，： | 1 |
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