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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | PHOTOELECTROCHEMICAL STUDY OF PASSIVE LAYERS ON COPPER ELECTRODES IN SOME ALKALINE MEDIA显示文摘PHOTOELECTROCHEMICALSTUDYOFPASSIVELAYERSONCOPPERELECTRODESINSOMEALKALINEMEDIA①A.Kamkina,1,ZhouGuodinga,XuQunjiebandB.H.cLooaE... | A. Kamkina,1, Zhou Guodinga, Xu Qunjieb and B. H.c Loo a Electrochemical Research Group, Shanghai Institute of Electric Power, Shanghai 200090, P. R. China b Corrosion Prevention Center, East China University of | 1998 | 中国有色金属学会会刊:英文版1998，8，2： | 2 |
| 3 | High-precision U-series dating of corals from Western Australia and implications for the timing and duration of the Last Interglacial显示文摘 | Stirling C H East T M McCulloch M T | 1995 | Earth and Planetary Science Letters1995，，135： | 1 |
| 4 | Ring oscillator using an RTD-HBT heterostructure显示文摘 | LIN C H YANG K EAST J R | 2001 | Journal of Korean Physical Society2001，39，3： | 1 |
| 5 | ADAMTS5 is the majoraggrecanase in mouse cartilage in vivo and in vitro显示文摘 | Stanton H Rogerson F M East C ] | 2005 | Nature2005，434，7033： | 1 |
| 6 | Recovery of submerged plants from high water stress in a large subtropical lake in Florida,USA显示文摘 | Sharfstein B Brady M A East T L Harwell M C Maki R P Rodusky A J | 2004 | Aquat Bot2004，78，： | 1 |
| 7 | Structure-property relationships in natural cellulose fibers Part I:characterizatiou显示文摘 | Ansari I A East G C Johnson D J | 1999 | Journal of Textile Institute1999，90，4： | 1 |
| 8 | Structure -property rela- tionships in natural cellulosic fibers Part I : Characterization 显示文摘 | ANSARI I A EAST G C JOHNSON D J | 1999 | Jourual of Textile Institute1999，90，3： | 1 |
| 9 | Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180显示文摘 | Messaritou G East L Roghi C | | 0，，22： | 1 |
| 10 | The Preparation of Poly(methyleneesters)显示文摘 | East G C Morshed M | 1982 | Polymer1982，23，： | 1 |
| 11 | Ring oscillator using an RTD-HBT heterostructure 显示文摘 | Lin C H Yang K East J R | 2001 | Journal of the Korean Physical Society2001，39，3： | 1 |
| 12 | 显示文摘 | Cimecioglu A L East G C Morshed M | 1988 | J Polym Sci Part A:Polym Chem1988，26，： | 1 |
| 13 | Polybiguanides: Synthesis and characterization of polybiguanides containing hexamethylene groups 显示文摘 | East G C Mclntyre J E Shao J | 1997 | Polymer1997，38，： | 1 |
| 14 | The physical properties of composite yarns produced by an electrostatic filament-charging method显示文摘 | TOU G T EAST G C | 1996 | J Text Inst1996，87，： | 1 |
| 15 | ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro显示文摘 | Stanton H Rogerson FM East C J | 2005 | Nature2005，434，7033： | 1 |
| 16 | Wet spinning of chitosan and the acetylaion of chitosan fibers显示文摘 | EAST G C QIN YIMIN | 1993 | Journal of applied polymer science1993，50，： | 1 |
| 17 | Bispectral analysis during eardiopulmonary bypass: the effect of hypothermia on the hypnotic state显示文摘 | Mathew J P Weatherwax K J East C J | 2001 | J Clin Anesth2001，13，4： | 1 |
| 18 | The dry spinning of dibutyrylchitin fibers显示文摘 | SZOSL EAST G C | 1995 | Journal of applied polymer science1995，58，： | 1 |
| 19 | ADAMTS-5 : the stray so far显示文摘 | Fosang k J Rogerson F M East C J | 2008 | Eur Cell Mater2008，15，9： | 1 |
| 20 | Polybiguanides: synthesis and characterization ofpolybiguanidescontaining hexamethylene groups显示文摘 | East G C Mclntyre J E Shao J | 1997 | polymer1997，38，15： | 1 |
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