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| 1 | Results of National Colorectal Cancer Screening Program in Croatia(2007-2011)显示文摘AIM:To study the epidemiologic indicators of uptake and characteristic colonoscopic findings in the Croatian National Colorectal Cancer Screening Program.METHODS:Colorectal cancer(CRC) was the second leading cause of cancer mortality in men(n = 1063,49.77/100 000),as well as women(n = 803,34.89/100 000) in Croatia in 2009.The Croatian National CRC Screening Program was established by the Ministry of Health and Social Welfare,and its implementation started in September,2007.The coordinators were recruited in each county institute of public health with an obligation to provide fecal occult blood testing(FOBT) to the participants,followed by colonoscopy in all positive cases.The FOBT was performed by hypersensitive guaiac-based Hemognost card test(Biognost,Zagreb).The test and short questionnaire were delivered to the home addresses of all citizens aged 50-74 years consecutively during a 3-year period.Each participant was required to complete the questionnaire and send it together with the stool specimen on three test cards back to the institute for further analysis.About 4% FOBT positive cases are expected in normal risk populations.A descriptive analysis was performed.RESULTS:A total of 1 056 694 individuals(born between 1933-1945 and 1952-1957) were invited to screening by the end of September 2011.In total,210 239(19.9%) persons returned the envelope with a completed questionnaire,and 181 102 of them returned it with a correctly placed stool specimen on FOBT cards.Until now,12 477(6.9%),FOBT-positive patients have been found,which is at the upper limit of the expected values in European Guidelines for Quality Assurance in CRC Screening and Diagnosis [European Union(EU) Guidelines].Colonoscopy was performed in 8541 cases(uptake 66%).Screening has identified CRC in 472 patients(5.5% of colonoscopied,3.8% of FOBT-positive,and 0.26% of all screened individuals).This is also in the expected range according to EU Guidelines.Polyps were found and removed in 3329(39% of colonoscopied) patients.The largest number of polyps were found in the left half of the colon:64%(19%,37% and 8% in the rectum,sigma,and descendens,respectively).The other 36% were detected in the proximal part(17% in the transverse colon and 19% in ceco-ascending colon).Small polyps in the rectum(5-10 mm in diameter),sigmoid and descending colon were histologically found to be tubular adenomas in 60% of cases,with a low degree of dysplasia,and 40% were classified as hyperplastic.Polyps of this size in the transverse or ceco-ascending colon in almost 20% had a histologically villous component,but still had a low degree of dysplasia.Polyps sized 10-20 mm in diameter were in 43% cases tubulovillous,and among them,32% had areas with a high degree of dysplasia,especially those polyps in the cecoascending or transverse part.The characteristics of the Croatian CRC Screening National Program in the first 3 years were as follows:relatively low percentage of returned FOBT,higher number of FOBT-positive persons but still in the range for population-based programs,and higher number of pathologic findings(polyps and cancers).CONCLUSION:These results suggest a need for intervention strategies that include organizational changes and educational activities to improve awareness of CRC screening usefulness and increase participation rates. | Miroslava Katii Nataa Antoljak Milan Kujundzi Valerija Stameni Dunja Skoko Poljak Danica Kramari Davor timac Marija Strnad Peikan Mirko amija Zdravko Ebling | 2012 | World Journal of Gastroenterology2012,18,32: | 2 |
| 2 | Correlations between oxida- tive DNA damage, oxidative stress and coenzyme Q10 in patients with coronary artery disease 显示文摘 | Kaya Y (ebl A SSylemez N | 2012 | Int J Med Sci2012,9,8: | 1 |
| 3 | Structure and Thermoelectric Properties of Nanocomposite Bismuth Telluride Prepared by Melt Spinning or by Partially Alloying with IV-VI Compounds显示文摘 | Ebling D G Jacquot A J?gle M | | 0,,: | 1 |
| 4 | Integrins in cancer treatment显示文摘 | Eble J A Haier J | | 0,,: | 1 |
| 5 | Laboratory decision-making during the classical swine fever epidemic of 1997- 1998 in The Netherlands显示文摘 | De Smit A J Eble P L De Kluijver E P | 1999 | Vet Microbiol1999,83,: | 1 |
| 6 | New N - terminal located muration within the POU1F1 -gene (PIT- 1 ) causes recessive combined pituitary hormone deficiency and variable phenotype 显示文摘 | Salemi S Besson A Eble A | 2003 | Growth Horm IGF Res2003,13,5: | 1 |
| 7 | Collagen XVI induces formation of focal contacts on intestinal myofibroblasts isolated from the normal and inflamed intestinal tract 显示文摘 | Ratzinger S Eble JA Pasoldt A | 2010 | Matrix Biology2010,29,3: | 1 |
| 8 | The neurobiology of reproductive development显示文摘 | Ebling F J Cronin A S | | 0,,16: | 1 |
| 9 | Radinfrequency catheter ablation of the atrial reduces inducibility and duration of atrial fibrillation in dogs 显示文摘 | Pride HP Eble JN | 1995 | Amm Thoraac Surg1995,91,5: | 1 |
| 10 | Regulation of growth-hormone-receptor gene expression by growth hormone and pegvisomant in human mesangial cells显示文摘 | Meinhardt U Eblé A Besson A | 2003 | Kidney Int2003,64,2: | 1 |
| 11 | New N-terminal located muration (Q4ter) within the POU1 F1-gene (PIT-1) causes recessive combined pituitary hormone deficiency and variable phenotype显示文摘 | Salemi S Besson A Eble A | 2003 | Growth Horm IGF Res2003,13,5: | 1 |
| 12 | Radiofrequency Catheter Ablation of the Atrial Reduces Inducibility and Duration of Atrial Fibrillation in Dogs显示文摘 | Elvan A Pride H P Eble J N | 1995 | Circulation1995,91,: | 1 |
| 13 | Vaccination of cattle only is sufficient to stop FMDV transmission in mixed populations of sheep and cattle显示文摘 | Bravo De Rueda C Dekker A Eblé P L | 2014 | Epidemiology and Infection2014,,: | 1 |
| 14 | Cytoohemical aspects of Mercenaria mercenaria hemooytes 显示文摘 | Moore C A Eble A F | 1977 | Biological Bulletin1977,152,1: | 1 |
| 15 | Aggregation numbers of cationic oligomeric surfactants : A time - resolved fluores- cence quenching study 显示文摘 | WATI'EBLED L LASCHEWSKY A MOUSSA A | 2006 | Langmuir2006,22,6: | 1 |
| 16 | Serological and mueo- sal immune response after vaccination and infection with FMDV in pigs 显示文摘 | Eble P L Bouma A Weedmesster K | 2007 | Vaccine2007,25,: | 1 |
| 17 | Mesenteric oxygen desaturation in an infant with congenital heart disease and necrotizing enterocolitis显示文摘 | Stapleton G E Eble B K Dickerson H A | 2007 | Tex Heart Inst J2007,34,4: | 1 |
| 18 | Laboratory experience during the classical swine fever virus epizootic in the Netherlands in 1997-1998显示文摘 | Desmit A J Eble P L Dekluijver E P | 2000 | Vet Microbiol2000,73,: | 1 |
| 19 | IL-6 and IL-10 induce decorin mRNA in endothelial cell but interaction with fibrillar collagen is essential for its translation显示文摘 | STRAZYNSKI M EBLE J A KRESSE H et a1 | 2004 | J Biol Chem2004,279,21: | 1 |
| 20 | Regional assessment of suitability of organic-rich gas shales for carbon sequestration:An example from the Devonian shales of the Illinois and Appalachian basins,Kentucky显示文摘 | Nuttall B C Drahovzal J A Eble C F | 2009 | AAPG Bulletin2009,59,2: | 1 |