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| 1 | Impact of preoperative chemoradiotherapy on survival in patients with resectable pancreatic cancer显示文摘AIM:To explore whether preoperative chemoradiation therapy improves survival of patients with pancreatic cancer undergoing resectional surgery. METHODS:Forty-seven patients with a malignant pancreatic tumor localized in the head or uncinate process of the pancreas underwent radical pancreaticoduodenectomy. Twenty-two received chemoradiation therapy (gemcitabine and radiation dose 50.4 Gy) before surgery (CRR) and 25 patients underwent surgery only (RO). The study was non-randomised. Patients were identified from a prospective database. RESULTS:The median survival time was 30.2 mo in the CRR group and 35.9 mo in the RO group. No statistically significant differences were found in subclasses according to lymph node involvement,TNM stages,tumor size,or perineural invasion. The one,three and five year survival rates were 81%,33% and 33%,respectively,in the CRR group and 72%,47% and 23%,respectively,in the RO group. In ductal adenocarcinoma,the median survival time was 27 mo in the CRR group and 20 mo in the RO group. No statistically significant differences were found in the above subclasses. The one,three and five year survival rates were 79%,21% and 21%,respectively,in the CRR group and 64%,50% and 14%,respectively,in the RO group. The overall hospital mortality rate was 2%. The morbidity rate was 45% in the CRR group and 32% (NS) in the RO group. CONCLUSION:Major multicenter randomized studies are needed to conclusively assess the impact of neoadjuvant treatment in the management of pancreatic cancer. | Plvi Vento Harri Mustonen Timo Joensuu Pivi Krkkinen Eero Kivilaakso Tuula Kiviluoto | 2007 | World Journal of Gastroenterology2007，13，21： | 8 |
| 2 | Fecal Transplantation, Through Colonoscopy, Is Effective Therapy for Recurrent Clostridium difficile Infection显示文摘 | Eero Mattila Raija Uusitalo–Sepp?l? Maarit Wuorela Laura Lehtola Heimo Nurmi Matti Ristikankare Veikko Moilanen Kimmo Salminen Maaria Sepp?l? Petri S. Mattila Veli–Jukka Anttila Perttu Arkkila | 2012 | Gastroenterology2012，，3： | 3 |
| 3 | Gut microbiota are related to Parkinson’s disease and clinical phenotype显示文摘 | Filip Scheperjans Velma Aho Pedro A. B. Pereira Kaisa Koskinen Lars Paulin Eero Pekkonen Elena Haapaniemi Seppo Kaakkola Johanna Eerola‐Rautio Marjatta Pohja Esko Kinnunen Kari Murros Petri Auvinen | 2015 | Mov Disord2015，，3： | 3 |
| 4 | The Outcome of Patients With Right Atrial Isomerism is Poor显示文摘 | Marianne P. Eronen Kristiina A. U. Aittom?ki Eero O. Kajantie Heikki I. Sairanen Erkki J. Pesonen | 2013 | Pediatric Cardiology2013，，2： | 3 |
| 5 | Faecal microbiota transplantation in patients with Clostridium difficile and significant comorbidities as well as in patients with new indications:A case series显示文摘Fecal microbiota transplantation(FMT) is effective in recurrent Clostridium difficile infection(r CDI). Knowledge of the safety and efficacy of FMT treatment in immune deficient patients is scarce. FMT has been suggested as a potential method for an increasing number of new indications besides r CDI. Among our FMT-treated r CDI patients, we reviewed those with major comorbidities: two human immunodeficiency virus patients, six haemodialysis patients, two kidney transplant patients, two liver transplant patients and a patient with chronic lymphatic leukaemia. We also reviewed those treated with FMT for indications other than r CDI: Salmonella carriage(two patients), trimethylaminuria(two patients), small intestinal bacterial overgrowth(SIBO;one patient), and lymphocytic colitis(one patient), as well as a common variable immunodeficiency patient with chronic norovirus infection and ESBL-producing Escherichia coli(E. coli) carriage. Of the thirteen r CDI patients treated with FMT, eleven cleared the CDI. The observed adverse events were not directly attributable to FMT. Concerning the special indications, both Salmonellas and ESBL-producing E. coli were eradicated. One trimethylaminuria patient and one SIBO-patient reported a reduction of symptoms. Three patients did not experience a benefit from FMT: chronic norovirus, lymphocytic colitis and the other fish malodour syndrome. There were no reported side effects in this group. FMT appeared to be safe and effective for immunocompromised patients with r CDI. FMT showed promise for the eradication of antibiotic-resistant bacteria, but further research is warranted. | Perttu Lahtinen Eero Mattila Veli-Jukka Anttila Jyrki Tillonen Matti Teittinen Pasi Nevalainen Seppo Salminen Reetta Satokari Perttu Arkkila | 2017 | World Journal of Gastroenterology2017，23，39： | 2 |
| 6 | The Neuroprotective Agent Memantine Induces Brain-Derived Neurotrophic Factor and trkB Receptor Expression in Rat Brain显示文摘 | Markéta Marvanová Merja Lakso Jarmo Pirhonen Hiroyoki Nawa Garry Wong Eero Castrén | 2001 | Molecular and Cellular Neuroscience2001，，3： | 2 |
| 7 | 开创压光技术新纪元——ValZone带式压光机显示文摘芬兰美卓造纸机械公司推出了最新开发的ValZone带式压光机,使得压光技术向前迈进了一大步。它采用了一种宽压区压光技术,可以大大改进纸和纸板压光的质量以及生产效率。该压光机的特点是采用长达1m的宽压区替代了传统的辊式压光机,压区由光滑的加热钢带和热辊形成,纸幅的两面可以在这个宽压区中同时得到压光, | Mika Viljanmaa Eero Halmari | 2007 | 中华纸业2007，28，8： | 2 |
| 8 | 美卓C160系列颚式破碎机 确保Zinkgruvan锌矿平稳运行显示文摘Zinkgruvan锌矿,坐落于瑞典斯德哥尔摩西南约200km处,是北欧历史最悠久的地下矿山之一,于1857年投入运行。采矿方法为盘区回采和阶梯式开采。 | Eero Hmlinen | 2012 | 矿业装备2012，，2： | 2 |
| 9 | Dislocation in Copper-A Molecular Dynamics Study显示文摘 | Pekka Heino Eero Ristolainen | 1999 | NanoStructured Materials1999，11，5： | 1 |
| 10 | Calibration of Laser Scanning Intensity Data using Brightness Targets. the Method Developed by the Finnish Geodetic Institute显示文摘 | Ants Vain Sanna Kaasalainen Juha Hyypp? Eero Ahokas | 2009 | Geodesy and Cartography2009，，3： | 1 |
| 11 | Eigenmode method for electromagnetic synthesis of diffractive elements with three dimensional profiles显示文摘 | Eero N Jari T | 1994 | J Opt Soc Am A1994，11，9： | 1 |
| 12 | The Influence of Acidic groups on the Physical Properties of High-Yield Pulps显示文摘 | Eddie Eriksson Eero Sjoestroem | 1968 | Tappi1968，，1： | 1 |
| 13 | Transforming growth factor- in the rat brain:inc_ rease after injury and inhibition of astrocyte prolifer_ ation显示文摘 | Eero Castren Rrinhard Kiefer | 1992 | The Journal of Cell Biology1992，117，2： | 1 |
| 14 | Random cascades on wavelet trees and their use in analyzing and modeling natural images显示文摘 | MARTIN J WAINWRIGHT EERO P SIMONCELLI ALAN S WILLAKY | 2001 | Applied and Computational Harmonic Analysis2001，，11： | 1 |
| 15 | Metabolomic changes in fatty liver can be modified by dietary protein and calcium during energy restriction显示文摘AIM: To characterise the effect of energy restriction (ER) on liver lipid and primary metabolite profile by using metabolomic approach. We also investigated whether the effect of energy restriction can be further enhanced by modif ication of dietary protein source and calcium. METHODS: Liver metabolomic profile of lean and obese C57Bl/6J mice (n = 10/group) were compared with two groups of weight-reduced mice. ER was performed on control diet and whey protein-based high-calcium diet (whey + Ca). The metabolomicanalyses were performed using the UPLC/MS based lipidomic platform and the HPLC/MS/MS based primary metabolite platform. RESULTS: ER on both diets significantly reduced hepatic lipid accumulation and lipid droplet size, while only whey + Ca diet significantly decreased blood glucose (P < 0.001) and serum insulin (P < 0.01). In hepatic lipid species the biggest reduction was in the level of triacylglycerols and ceramides while the level of cholesterol esters was significantly increased during ER. Interestingly, diacylglycerol to phospholipid ratio, an indicator of relative amount of diabetogenic diglyceride species, was increased in the control ER group, but decreased in the whey + Ca ER group (P < 0.001, vs obese). ER on whey + Ca diet also totally reversed the obesity induced increase in the relative level of lipotoxic ceramides (P < 0.001, vs obese; P > 0.05, vs lean). These changes were accompanied with up-regulated TCA cycle and pentose phosphate pathway metabolites. CONCLUSION: ER-induced changes on hepatic metabolomic profile can be significantly affected by dietary protein source. The therapeutic potential of whey protein and calcium should be further studied. | Taru K Pilvi Tuulikki Seppnen-Laakso Helena Simolin Piet Finckenberg Anne Huotari Karl-Heinz Herzig Riitta Korpela Matej Orei Eero M Mervaala | 2008 | World Journal of Gastroenterology2008，14，28： | 1 |
| 16 | The preparation of reusable magnetic and photocatalytic composi- te nanofibers by electrospinning and atomic layer deposition 显示文摘 | Eero Santala Marianna Kemell Markku Leskel | 2009 | Nanotechnology2009，20，： | 1 |
| 17 | The impact of organizational and national cultural differences on social conflict and knowl- edge transfer in international acquisitions 显示文摘 | Eero V Riikka S Ingmar B | 2012 | Journal of Management Studies2012，491，1： | 1 |
| 18 | Evaluating the Carbon Emissions of theLow Carbon City : A Novel Approach for Consumer Based Allocation显示文摘 | Eero Paloheimo Olli Salmi | 2013 | CITIES2013，30，1： | 1 |
| 19 | Dislocation Initiation in Copper-A Molecular Dynamics Study显示文摘 | Eero Ristolainen | 1999 | Nanostructured Materials1999，11，5： | 1 |
| 20 | Solder balling of lead-free solder pastes 显示文摘 | Minna Arra Dongkai Shangguan Ristolainen Eero | 2002 | J Electron Mater2002，31，11： | 1 |
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